Isolation, Identification and Antibiotic Resistance Profile of Indigenous Bacterial Isolates from Urinary Tract Infection Patients

2004 ◽  
Vol 7 (12) ◽  
pp. 2051-2054 ◽  
Author(s):  
Nadia Gul . ◽  
Talat Y. Mujahid . ◽  
Samia Ahmad .
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Bacterial Isolates ◽  
Resistance Profile ◽  
Antibiotic Resistance Profile

scholarly journals Urinary tract infection and antimicrobial resistance profile in patients attending Nemba District Hospital in Rwanda

2020 ◽  
Vol 11 (6) ◽  
pp. 101-105
Author(s):  
Munyemana Jean Bosco ◽  
Bikorimana Jonas ◽  
Kantarama Evelyne ◽  
Kabanyana Pauline
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Tract Infection ◽  
Antimicrobial Agents ◽  
District Hospital ◽  
Coagulase Negative Staphylococcus ◽  
Bacterial Isolates ◽  
Resistance Profile ◽  
Antimicrobial Resistance Profile

Background: About 150 million people worldwide are diagnosed with urinary tract infection (UTI) every year and more than half of women get UTI at least once in their lifetimes. Overuse and misuse of antibiotics have contributed to the growing problem of resistance amongst uropathogenic bacteria making it hard to treat. Aims and Objectives: This study aimed to determine bacteria causing UTIs and their antibiotic resistance profile among patients attending Nemba District Hospital in Rwanda. Materials and Methods: A retrospective study design was used and 267 patient’s data with positive urine culture were reviewed from microbiology laboratory logbooks. Results: In this study, UTI was more frequent in female 180(67.4%) than male 87(32.6%). The most frequently isolated bacteria to cause UTI were Escherichia coli (56.93%) followed by Staphylococcus aureus (28.46%), Proteus spp. (4.49%), Klebsiella spp. (3.75%), Morganella morganii (1.87%), Coagulase Negative Staphylococcus (1.50%), Neisseria gonorrhea (1.12%), Enterobacter spp. (1.12%) and Citrobacter spp. (0.7%). There was a high antimicrobial resistance profile among bacterial isolates. The most commonly used antimicrobial agents including third-generation cephalosporin were resistant to bacterial isolates at a higher rate. Conclusion: These findings suggest continued antimicrobial resistance surveillance and special precautions should be taken for empirical treatment referring to local antimicrobial resistance.

The Benefits and Harms of Antibiotic Prophylaxis for Urinary Tract Infection in Older Adults

2021 ◽  
Author(s):  
Bradley J Langford ◽  
Kevin A Brown ◽  
Christina Diong ◽  
Alex Marchand-Austin ◽  
Kwaku Adomako ◽  
...  
Keyword(s):  
Older Adults ◽  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Prophylaxis ◽  
Bloodstream Infection ◽  
Antibiotic Treatment ◽  
Positive Culture ◽  
Clostridioides Difficile

Abstract Background The role of antibiotics in preventing urinary tract infection (UTI) in older adults is unknown. We sought to quantify the benefits and risks of antibiotic prophylaxis among older adults. Methods We conducted a matched cohort study comparing older adults (≥66 years) receiving antibiotic prophylaxis, defined as antibiotic treatment for ≥30 days starting within 30 days of a positive culture, with patients with positive urine cultures who received antibiotic treatment but did not receive prophylaxis. We matched each prophylaxis recipient to 10 nonrecipients based on organism, number of positive cultures, and propensity score. Outcomes included (1) emergency department (ED) visit or hospitalization for UTI, sepsis, or bloodstream infection within 1 year; (2) acquisition of antibiotic resistance in urinary tract pathogens; and (3) antibiotic-related complications. Results Overall, 4.7% (151/3190) of UTI prophylaxis patients and 3.6% (n = 1092/30 542) of controls required an ED visit or hospitalization for UTI, sepsis, or bloodstream infection (hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.12–1.57). Acquisition of antibiotic resistance to any urinary antibiotic (HR, 1.31; 95% CI, 1.18–1.44) and to the specific prophylaxis agent (HR, 2.01; 95% CI, 1.80–2.24) was higher in patients receiving prophylaxis. While the overall risk of antibiotic-related complications was similar between groups (HR, 1.08; 95% CI, .94–1.22), the risk of Clostridioides  difficile and general medication adverse events was higher in prophylaxis recipients (HR [95% CI], 1.56 [1.05–2.23] and 1.62 [1.11–2.29], respectively). Conclusions Among older adults with UTI, the harms of long-term antibiotic prophylaxis may outweigh their benefits.

scholarly journals Nontypable Haemophilus influenzae Septicemia and Urinary Tract Infection Associated with Renal Stone Disease

2018 ◽  
Vol 12 (1) ◽  
pp. 243-247
Author(s):  
Marianne Stærk ◽  
Sara A. Tolouee ◽  
Jens J. Christensen
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Haemophilus Influenzae ◽  
Renal Stone ◽  
Stone Disease ◽  
Upper Respiratory Tract ◽  
Renal Stone Disease ◽  
Tract Infections

Introduction: Haemophilus influenzae commonly causes upper respiratory tract infections and has only rarely been reported etiology of urinary tract infections. Since the introduction of the Haemophilus influenzae b (Hib) vaccine, non-typable haemophilus species now cause the majority of invasive disease in Europe. Case Report: We report a case of an adult man with non-typable Haemophilus influenzae septicemia, urinary tract infection and bilateral renal stone disease. The patient presented with right sided flank pain and a CT scan showed bilateral renal stones and a right sided ureteral stone causing obstruction. Results and Discussion: Haemophilus influenzae was identified in blood and urine and despite a tendency of increasing antibiotic resistance among Haemophilus influenzae, our strain was susceptible to all antibiotics tested. Treatment consisted of 3 days of intravenous cefuroxime, insertion of a right sided JJ ureteric stent and 5 days of peroral ciprofloxacin after discharge. Physicians and microbiologists should be aware of Haemophilus influenzae as a possible urinary tract pathogen, especially when urinary tract abnormalities are present, and take the risk of antibiotic resistance into consideration at initial treatment.

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