scholarly journals Relationship between quality of platelet concentrate and platelet recovery rate of leukocyte removal filter.

1995 ◽  
Vol 41 (5) ◽  
pp. 428-434
Author(s):  
Takayoshi Asai ◽  
Michihiro Ito ◽  
Kiyoshi Hiruma ◽  
Yoko Nakajima
2016 ◽  
Vol 62 (5) ◽  
pp. 592-600 ◽  
Author(s):  
Hidekazu Onodera ◽  
Yuji Kaneko ◽  
Akihiro Fuchizaki ◽  
Megumi Ichisugi ◽  
Katsuhiko Kurihara ◽  
...  

2021 ◽  
Vol 28 (2) ◽  
pp. 179-183
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Kashfia Islam ◽  
ABM Al Mamun

Background: The platelet transfusions help in prevention of bleeding related complications and thus prevents morbidity and mortality in thrombocytopenic patients. Platelet transfusion plays an important role in the treatment of haematological, oncological, surgical, and transplant patients. Platelets are transfused by two methods i) by fractionation of whole blood and ii) by platelet apheresis. Over the last decade there has been a trend towards the use of SDPs rather than pooled random donor platelets in thrombocytopenic patients. Optimization of platelet yield is an emerging issue to identify factors which may help in selecting donors to obtain higher platelet yields in shorter time and consequently better clinical outcome. Objective: The quality of single donor platelets (SDP) in terms of yield influences the platelet recovery in the recipient. The aim was to identify the SDP donor factors that influence platelet yield. Methods: The study was undertaken at transfusion medicine department, DMCH from 1st January 2017 to 31st December 2017. The study included 350 plateletpheresis procedures. All procedures were performed according to manufacturer’s manual and standard operating procedure. Results: During the period of study, 350 platelet pheresis donors were studied. All of the donors were male. Platelet yield showed high statistical significance with pre donation platelet count and its indices. (p=0.000). Statistical significant negative correlation was seen between pre donation Hb concentration and the platelet yield. (p =0.005). No statistical significance was seen height (p=0.933), weight (p=0.760) of donor on platelet yield. Conclusion: Platelet recovery in the patient is influenced by the transfused dose of platelets, which in turn is dependent on the quality of the platelet product in terms of yield. Various donor factors such as pre donation platelet count and haemoglobin concentration may affect platelet yield. J Dhaka Medical College, Vol. 28, No.2, October, 2019, Page 179-183


2012 ◽  
Vol 50 (No. 4) ◽  
pp. 149-158 ◽  
Author(s):  
V. Havlicek ◽  
M. Lopatarova ◽  
S. Cech ◽  
R. Dolezel ◽  
T. Huber ◽  
...  

Routine access to the bovine oviduct for in vivo culture accomplishes various demands on embryo production for scientific as well as commercial purposes. The experiments conducted in the present study focused on the efficiency of recovery methods after temporary in vivo culture of bovine embryos in oviducts of the homologous species using transvaginal endoscopy (Experiment I) and on the quality assessment of recovered blastocysts (Experiment II). In Experiment I in vitro matured oocytes were fertilized, cultured for 1 to 3 days and transferred unilaterally into the ipsilateral oviducts of 54 heifers by the means of transvaginal endoscopy. After 4 to 6 days of in vivo culture embryos were re-collected either by non-surgical flushing of uterine horns (U-group) or by combined flushing of the oviducts and uterine horns (OU-group). In total the recovery rate was 38.4% (780/2029). After flushing at day seven, 106 blastocysts (blastocyst rate: 13.6% ) were found. The additional 24 h of in vitro culture (day eight) resulted in 153 blastocysts (blastocyst rate: 19.6% ). The recovery rate in the OU-group was twice as efficient as in the U-group (390/1358 vs. 390/671, P < 0.01). The recovery rates among the different stages of transferred embryos did not differ significantly; likewise cross-effects among the stages and the recovery methods were non-significant. The recovery methods (P < 0.001) and the interaction between the recovery methods and the stages of transferred embryos (P < 0.01) had an influence on blastocyst yields on day seven (U-group 37/1358 vs. OU-group 69/671) and day eight (U-group 48/1358 vs. OU-group 105/671). In Experiment II embryo quality was assessed by the survival rate of blastocysts after freezing in ethylene glycol. Day seven embryos were produced in vitro (in vitro group D7) or by IVM/IVF followed by a combined culture procedure (2 to 3 days in vitro prior to 4 to 5 days in vivo) (in vivo group D7) or after superovulation and collection at day seven (superovulation group). Embryos from in vitro group D7 re-expanded only for 6 h after thawing, embryos from in vivo group D7 and superovulation group were alive for 24 h and 72 h of culture, respectively. Only embryos derived by superovulation showed hatching activity. Blastocysts from the in vitro group D7 and the in vivo group D7 that were held in culture medium for additional 24 h (day eight) showed an analogous post-thawing culture behaviour. In conclusion, the results of the present study demonstrated that some embryos transferred for in vivo culture remain in the oviduct even at day seven. Hence, combined flushing of oviducts and uterine horns after in vivo culture in the bovine oviduct is necessary for effective embryo re-collection. The quality of recovered embryos after temporary in vivo culture assessed by cryotolerance was in-between those produced in vitro or recovered after superovulation.


2008 ◽  
Vol 106 (1-2) ◽  
pp. 208-214 ◽  
Author(s):  
Sait Sendag ◽  
Yunus Cetin ◽  
Muhammet Alan ◽  
Klaus-Gerd Hadeler ◽  
Heiner Niemann

2021 ◽  
Author(s):  
Rasheed Ali Rashid ◽  
Ameer A. Alaqeedy ◽  
Raid M. Al-Ani

Abstract Although parosmia is a common problem in the era of the COVID-19 pandemic, few studies assessed the demographic and clinical aspects of this debilitating symptom. We aimed to evaluate the socio-clinical characteristics and outcome of various options of treatment of individuals with parosmia due to COVID-19 infection. The study was conducted at two main Hospitals in the Ramadi and Tikrit cities, Iraq, on patients with a chief complaint of parosmia due to COVID-19 disease. The study involved 7 months (August 2020-February 2021). Detailed demographic and clinical characteristics and treatment options with their outcome were recorded and analyzed. Out of 268 patients with parosmia, there were 197 (73.5%) females. The majority were from age group ≤ 30 years (n = 188, 70.1%), housewives (n = 150, 56%), non-smokers (n = 222, 82.8%), and associated with dysgeusia (n = 207, 77.2%) but not associated with nasal symptoms (n = 266, 99.3%). All patients have complained of anosmia (89.9%) or hyposmia (10.1%). Troposmia was reported in the majority of participants. The majority of the patients were suffering from severe parosmia (65.7%). Around 3 quarters of the cases were presented in ≤ 4 months. Altered quality of life (AQL) was presented in 91.8% of subjects, and there was a significant association with the presence of dysgeusia and type and severity of parosmia. The smoking habit didn't show a significant association with AQL, the severity of parosmia, and the recovery rate. Most of the odor group was the most triggering stimuli eliciting parosmia, while, the sewage was the response odor in above 50% of the cases. The recovery rate was poor with olfactory training plus either tonics or local and systemic steroids. Parosmia due to COVID-19 infection is a common problem with poor results in the short-term treatment and follow-up. The AQL was seen in a greater proportion of patients and strongly associated with the presence of dysgeusia, type, and severity of parosmia.


2012 ◽  
Vol 38 (6) ◽  
pp. 733-739 ◽  
Author(s):  
Massimo Del Fabbro ◽  
Valentina Ceresoli ◽  
Alessandra Lolato ◽  
Silvio Taschieri

2021 ◽  
Vol 7 (5) ◽  
pp. 3218-3225
Author(s):  
Lixia Wu ◽  
Xiaoling Chen ◽  
Lin Sun

Objective: To analyze the effect of rapid rehabilitation nursing on the recovery rate of gastrointestinal function and quality of life in elderly patients undergoing radical resection of colorectal cancer. Methods: 120 elderly patients with colorectal cancer admitted to our hospital from January 2018 to February 2020 were divided into two groups, the routine group (n = 60) was given routine nursing intervention, and the rapid group (n = 60) was given rapid rehabilitation nursing intervention. Postoperative general condition (including postoperative ambulation, exhausting, defecation, hospital stay and complications), pain degree score, abdominal distension score, gastrointestinal reaction score and changes of serum inflammatory factors were recorded in the two groups. Differences in quality of life were recorded at 1 and 6 months after surgery. Results: The general conditions, such as first ambulation, first exhausting, defecation and hospital stay were shorter in the rapid group than those in the routine group, and the incidence rate of postoperative complications was lower in the rapid group than that in the routine group (P<0.05). At 6h after operation, abdominal distension score and gastrointestinal reaction score were similar in the two groups (P>0.05); at 24h after operation, abdominal distension score in the rapid group was lower than that in the routine group (P<0.05), and gastrointestinal reaction score was similar to that in the routine group (P>0.05); at 48h after operation, abdominal distension score and gastrointestinal reaction score in the rapid group were lower than that in the routine group (P<0.05); at 72h after operation, abdominal distension score in the rapid group was lower than that in the routine group (P<0.05), and gastrointestinal reaction score was similar to that in the routine group (P>0.05). At 24h, 48h and 72h after operation, the levels of IL-6 and IL-8 in the two groups were higher than those before operation (P<0.05), and the levels of IL-6 and IL-8 in the rapid group were lower than those in the routine group (P<0.05). At 2h after operation, the VAS scores of the two groups were similar (P>0.05). At 6h,12h and 24h after operation, the VAS scores of the rapid group were lower than those of the routine group (P<0.05). At 1 month after operation, the scores of cognitive function, role function and emotional function in the rapid group were higher than those in the routine group (P<0.05), and the scores of physical function, social function and general health status were relatively similar to those in the routine group (P>0.05); at 6 months after operation, the scores of ORTCQLQ-c30 in the rapid group were higher than those in the routine group (P<0.05). Conclusion: Rapid rehabilitation nursing can promote the postoperative recovery of gastrointestinal function, alleviate the degree of pain, reduce the incidence of complications and improve the quality of life in elderly patients undergoing radical resection of colorectal cancer.


1996 ◽  
Vol 45 (4) ◽  
pp. 719-726 ◽  
Author(s):  
M. Huhtinen ◽  
E. Koskinen ◽  
J.A. Skidmore ◽  
W.R. Allen
Keyword(s):  

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