Vitamin E Deficiency Decreases Long-Chain PUFA in Zebrafish (Danio rerio)

The long-chain polyunsaturated fatty acids (PUFA) docosahexaenoic acid (DHA) and arachidonic acid (AA) are the most abundant fatty acids in the brain and are vital for its correct development and for that of the nervous system (Huang and Craig-Schmidt, 1996). Ruminant diets are low in DHA and its precursor alpha-linolenic acid. In addition, dietary PUFAs are substantially hydrogenated in the rumen. Consequently, it may be argued that the diets of pregnant and lactating ewes may be deficient in DHA and that a response to supplementation may be observed. Studies involving the supplementation of pregnant ewes with supraoptimal levels of vitamin E have shown that lambs born to supplemented dams are more vigorous immediately after birth and have higher liveweight gains (Merrell, 1998). The objective of this experiment was to investigate the effects of dietary long-chain PUFA in combination with vitamin E supplementation of ewes on ewe and lamb performance.

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Gene Expression of CRAL_TRIO Family Proteins modulated by Vitamin E Deficiency in Zebrafish (Danio Rerio)

The Journal of Nutritional Biochemistry ◽

10.1016/j.jnutbio.2021.108801 ◽

2021 ◽

pp. 108801

Author(s):

Alexander T. Watt ◽

Brian Head ◽

Scott W. Leonard ◽

Robyn L. Tanguay ◽

Maret G. Traber

Keyword(s):

Gene Expression ◽

Vitamin E ◽

Danio Rerio ◽

Vitamin E Deficiency

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The effect of vitamin E and long-chain polyunsaturated fatty acid supplementation of pregnant and lactating ewes on the transfer of vitamin E to the lamb

Proceedings of the British Society of Animal Science ◽

10.1017/s1752756200012205 ◽

2003 ◽

Vol 2003 ◽

pp. 61-61

Author(s):

J. L. Capper ◽

R. G. Wilkinson ◽

E. Kasapidou ◽

S. E. Pattinson ◽

A. M. Mackenzie ◽

...

Keyword(s):

Vitamin E ◽

Maternal Diet ◽

Dietary Vitamin ◽

Chain Polyunsaturated Fatty Acid ◽

Biochemical Mechanism ◽

Pufa Supplementation ◽

Fatty Acid Supplementation ◽

Chain Pufa ◽

Vitamin E Status ◽

Long Chain

It is reported that supplementing pregnant ewes with supra-optimal levels of vitamin E improves neonatal lamb vigour and growth rate (Merrell, 1998). The biochemical mechanism behind these observations has yet to be elucidated as several studies report negligible placental vitamin E transfer in ruminants (Van Saun et al., 1989); consequently, lambs may be clinically deficient in this nutrient at birth and achieve a satisfactory vitamin E status via colostrum ingestion. Lamb vitamin E status may be further diminished by the addition of polyunsaturated fatty acids (PUFAs) to the maternal diet. However, PUFA supplementation demonstrably enhances foetal and neonatal development in human studies (Morley, 1998) although these effects have not been investigated in ruminants to any depth. The objective of this experiment was to investigate the effects of dietary vitamin E in combination with long-chain PUFA supplementation of ewes on ewe and lamb performance.

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