scholarly journals A Systematic Review of Clinical Decision Support Systems in Alzheimer’s Disease Domain

Author(s):  
Sherimon P.C. ◽  
Vinu Sherimon ◽  
Preethii S.P. ◽  
Rahul Nair ◽  
Renchi Mathew

Dementia is one of the major public health issues faced by the world. Alzheimer’s disease (AD) is the most common form of dementia targeting old age groups around the world. It is a neurodegenerative condition with memory loss as its early symptom. Unfortunately, there is no cure for this disease currently. So various research in the medical and technical fields are being conducted to help people with Alzheimer’s. Many studies focus on early diagnosis of Alzheimer’s disease using clinical decision support system (CDSS) so that the progression of the disease can be slowed down to a great extent. In this context, we have undertaken a research to design and implement an ontology based Clinical decision support system for Alzheimer’s disease in Sultanate of Oman. A semantic knowledgebase (ontology) will be the core component of our Clinical decision support system. The objective of this research paper is two-fold (a) review the medical aspects of Alzheimer’s disease, and (b) review the available clinical decision support system based on ontology, robotics, and mobile applications in Alzheimer domain. Research articles published during 2011- 2020 in PubMed, Google scholar, Elsevier, SpringerLink and IEEE journals were reviewed. We found that there is various clinical decision support system which can aid physicians in suggesting diagnosis, and treatment of Alzheimer’s disease.

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1309-P
Author(s):  
JACQUELYN R. GIBBS ◽  
KIMBERLY BERGER ◽  
MERCEDES FALCIGLIA

2020 ◽  
Vol 16 (3) ◽  
pp. 262-269
Author(s):  
Tahere Talebi Azad Boni ◽  
Haleh Ayatollahi ◽  
Mostafa Langarizadeh

Background: One of the greatest challenges in the field of medicine is the increasing burden of chronic diseases, such as diabetes. Diabetes may cause several complications, such as kidney failure which is followed by hemodialysis and an increasing risk of cardiovascular diseases. Objective: The purpose of this research was to develop a clinical decision support system for assessing the risk of cardiovascular diseases in diabetic patients undergoing hemodialysis by using a fuzzy logic approach. Methods: This study was conducted in 2018. Initially, the views of physicians on the importance of assessment parameters were determined by using a questionnaire. The face and content validity of the questionnaire was approved by the experts in the field of medicine. The reliability of the questionnaire was calculated by using the test-retest method (r = 0.89). This system was designed and implemented by using MATLAB software. Then, it was evaluated by using the medical records of diabetic patients undergoing hemodialysis (n=208). Results: According to the physicians' point of view, the most important parameters for assessing the risk of cardiovascular diseases were glomerular filtration, duration of diabetes, age, blood pressure, type of diabetes, body mass index, smoking, and C reactive protein. The system was designed and the evaluation results showed that the values of sensitivity, accuracy, and validity were 85%, 92% and 90%, respectively. The K-value was 0.62. Conclusion: The results of the system were largely similar to the patients’ records and showed that the designed system can be used to help physicians to assess the risk of cardiovascular diseases and to improve the quality of care services for diabetic patients undergoing hemodialysis. By predicting the risk of the disease and classifying patients in different risk groups, it is possible to provide them with better care plans.


2021 ◽  
pp. 0310057X2097403
Author(s):  
Brenton J Sanderson ◽  
Jeremy D Field ◽  
Lise J Estcourt ◽  
Erica M Wood ◽  
Enrico W Coiera

Massive transfusions guided by massive transfusion protocols are commonly used to manage critical bleeding, when the patient is at significant risk of morbidity and mortality, and multiple timely decisions must be made by clinicians. Clinical decision support systems are increasingly used to provide patient-specific recommendations by comparing patient information to a knowledge base, and have been shown to improve patient outcomes. To investigate current massive transfusion practice and the experiences and attitudes of anaesthetists towards massive transfusion and clinical decision support systems, we anonymously surveyed 1000 anaesthetists and anaesthesia trainees across Australia and New Zealand. A total of 228 surveys (23.6%) were successfully completed and 227 were analysed for a 23.3% response rate. Most respondents were involved in massive transfusions infrequently (88.1% managed five or fewer massive transfusion protocols per year) and worked at hospitals which have massive transfusion protocols (89.4%). Massive transfusion management was predominantly limited by timely access to point-of-care coagulation assessment and by competition with other tasks, with trainees reporting more significant limitations compared to specialists. The majority of respondents reported that they were likely, or very likely, both to use (73.1%) and to trust (85%) a clinical decision support system for massive transfusions, with no significant difference between anaesthesia trainees and specialists ( P = 0.375 and P = 0.73, respectively). While the response rate to our survey was poor, there was still a wide range of massive transfusion experience among respondents, with multiple subjective factors identified limiting massive transfusion practice. We identified several potential design features and barriers to implementation to assist with the future development of a clinical decision support system for massive transfusion, and overall wide support for a clinical decision support system for massive transfusion among respondents.


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