Optimization Method of the Transcutaneous Energy Transmission System with Given Output Power

2012 ◽  
Vol 195-196 ◽  
pp. 1169-1174
Author(s):  
Liang Yu Bai ◽  
Yu Zheng ◽  
Hou Jun Tang
Keyword(s):  
Output Power ◽  
Magnetic Coupling ◽  
Optimization Method ◽  
Transmission Efficiency ◽  
Energy Transmission ◽  
Bifurcation Phenomenon ◽  
Design Variables ◽  
Transcutaneous Energy Transmission

Transcutaneous energy transmission (TET) systems are designed to deliver power from an in vitro primary power source to in vivo implantable secondary over relatively large air gaps via magnetic coupling. This paper proposes an optimization method with given output power to meet different practical application. The transmission efficiency is the objective function; primary and secondary coils are design variables; constraints are based on bifurcation phenomenon and components peak over-voltage and peak withstand current. We have used MATLAB/ SIMULINK to verify the analytical results.

scholarly journals Study on electromagnetic characteristics of the magnetic coupling resonant coil for the wireless power transmission system

2018 ◽  
Vol 16 (1_suppl) ◽  
pp. 140-149 ◽  
Author(s):  
Zhongxian Wang ◽  
Yiping Liu ◽  
Yonggeng Wei ◽  
Yilin Song
Keyword(s):  
Output Power ◽  
Power Transmission ◽  
Magnetic Coupling ◽  
Transmission Efficiency ◽  
Transmission System ◽  
The Novel ◽  
Wireless Power ◽  
Energy Transmission ◽  
Coil Structure ◽  
The Relationship

Background: The resonant coil design is taken as the core technology in the magnetic coupling resonant wireless power transmission system, which achieves energy transmission by the coupling of the resonant coil. This paper studies the effect of the resonant coil on energy transmission and the efficiency of the system. Combining a two-coil with a three-coil system, the optimum design method for the resonant coil is given to propose a novel coil structure. Methods: First, the co-simulation methods of Pspice and Maxwell are used. When the coupling coefficient of the resonant coil is different, the relationship between system transmission efficiency, output power, and frequency is analyzed. When the self-inductance of the resonant coil is different, the relationship between the performance and frequency of the system transmission is analyzed. Then, two-coil and three-coil structure models are built, and the parameters of the magnetic field of the coils are calculated and analyzed using the finite element method. In the end, a dual E-type simulation circuit model is used to optimize the design of the novel resonance coil. Results: The co-simulation results show that the coupling coefficients of the two-coil, three-coil, and novel coil systems are 0.017, 0.17 and 0.0126, respectively. The power loss of the novel coil is 16.4 mW. Conclusions: There is an obvious improvement in the three-coil system, which shows that the magnetic leakage of the field and the energy coupling are relatively small. The new structure coil has better performance, and the load loss is lower; it can improve the system output power and transmission efficiency.

Optimization of Transcutaneous Energy Transmission Systems Suitable for Left Ventricular Assist Devices

2013 ◽  
Vol 7 (2) ◽  
Author(s):  
Kelly Byron ◽  
Vlad Bluvshtein ◽  
Lori Lucke ◽  
John Pauly
Keyword(s):  
Pump Current ◽  
Optimization Method ◽  
Left Ventricular ◽  
Ventricular Assist Devices ◽  
Left Ventricular Assist Devices ◽  
Energy Transmission ◽  
Transmission Systems ◽  
Ventricular Assist ◽  
Assist Devices ◽  
Transcutaneous Energy Transmission

Transcutaneous energy transmission systems (TETS) wirelessly transmit power through the skin. TETS is particularly desirable for ventricular assist devices (VAD), which currently require cables through the skin to power the implanted pump. Current implantable TETS systems are not optimized for high power VAD applications. Optimizing the inductive link of the TET system is a multi-parameter problem. Most current techniques to optimize the design simplify the problem by combining parameters leading to sub-optimal solutions. In this paper we present an optimization method using a genetic algorithm to handle a larger set of parameters, which leads to a more optimal design.

IN VIVO LONG TERM EVALUATION OF TRANSCUTANEOUS ENERGY TRANSMISSION FOR TATALLY IMPLANTABLE ARTIFITIAL HEART

ASAIO Journal ◽  
2000 ◽  
Vol 46 (2) ◽  
pp. 170 ◽  
Author(s):  
Y. Kakuta ◽  
E. Tatsumi ◽  
Y. Taenaka ◽  
K. Uesho ◽  
A. Homma ◽  
...  
Keyword(s):  
Energy Transmission ◽  
Transcutaneous Energy Transmission ◽  
Term Evaluation

scholarly journals A Chrysodeixis chalcites Single-Nucleocapsid Nucleopolyhedrovirus Population from the Canary Islands Is Genotypically Structured To Maximize Survival

2013 ◽  
Vol 79 (24) ◽  
pp. 7709-7718 ◽  
Author(s):  
Alexandra Bernal ◽  
Oihane Simón ◽  
Trevor Williams ◽  
Delia Muñoz ◽  
Primitivo Caballero
Keyword(s):  
Canary Islands ◽  
Transmission Efficiency ◽  
Wild Type ◽  
Content Type ◽  
Biological Insecticide ◽  
In The Wild ◽  
Type Population ◽  
Chrysodeixis Chalcites

ABSTRACTAChrysodeixis chalcitessingle-nucleocapsid nucleopolyhedrovirus wild-type isolate from the Canary Islands, Spain, named ChchSNPV-TF1 (ChchTF1-wt), appears to have great potential as the basis for a biological insecticide for control of the pest. An improved understanding of the genotypic structure of this wild-type strain population should facilitate the selection of genotypes for inclusion in a bioinsecticidal product. Eight genetically distinct genotypes were clonedin vitro: ChchTF1-A to ChchTF1-H. Quantitative real-time PCR (qPCR) analysis confirmed that ChchTF1-A accounted for 36% of the genotypes in the wild-type population. In bioassays, ChchTF1-wt occlusion bodies (OBs) were significantly more pathogenic than any of the component single-genotype OBs, indicating that genotype interactions were likely responsible for the pathogenicity phenotype of wild-type OBs. However, the wild-type population was slower killing and produced higher OB yields than any of the single genotypes alone. These results strongly suggested that the ChchTF1-wt population is structured to maximize its transmission efficiency. Experimental OB mixtures and cooccluded genotype mixtures containing the most abundant and the rarest genotypes, at frequencies similar to those at which they were isolated, revealed a mutualistic interaction that restored the pathogenicity of OBs. In OB and cooccluded mixtures containing only the most abundant genotypes, ChchTF1-ABC, OB pathogenicity was even greater than that of wild-type OBs. The ChchTF1-ABC cooccluded mixture killed larvae 33 h faster than the wild-type population and remained genotypically and biologically stable throughout five successive passagesin vivo. In conclusion, the ChchTF1-ABC mixture shows great potential as the active ingredient of a bioinsecticide to controlC. chalcitesin the Canary Islands.

scholarly journals SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Wei Huang ◽  
Mingjia Qu ◽  
Lu Li ◽  
Tao Liu ◽  
Miaoman Lin ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Drug Loading ◽  
Transmission Efficiency ◽  
Inflammatory Factors ◽  
Bioactive Substances ◽  
Locomotor Recovery ◽  
Cord Injury

Abstract Background How to obtain a small interfering RNA (siRNA) vector has become a moot point in recent years. Exosomes (Exo) show advantages of long survival time in vivo, high transmission efficiency, and easy penetration across the blood-spinal cord barrier, renowned as excellent carriers of bioactive substances. Methods We applied mesenchymal stem cell (MSC)-derived exosomes as the delivery of synthesized siRNA, which were extracted from rat bone marrow. We constructed exosomes-siRNA (Exo-siRNA) that could specifically silence CTGF gene in the injury sites by electroporation. During the administration, we injected Exo-siRNA into the tail vein of SCI rats, Results In vivo and in vitro experiments showed that Exo-siRNA not only effectively inhibited the expressions of CTGF gene, but quenched inflammation, and thwarted neuronal apoptosis and reactive astrocytes and glial scar formation. Besides, it significantly upregulated several neurotrophic factors and anti-inflammatory factors, acting as a facilitator of locomotor recovery of rats with spinal cord injury (SCI). Conclusions In conclusion, this study has combined the thoroughness of gene therapy and the excellent drug-loading characteristics of Exo for the precise treatment of SCI, which will shed new light on the drug-loading field of Exo.

scholarly journals Replication Variance of African and Asian Lineage Zika Virus Strains in Different Cell Lines, Mosquitoes and Mice

2021 ◽  
Vol 9 (6) ◽  
pp. 1250
Author(s):  
Tey Putita Ou ◽  
Heidi Auerswald ◽  
Saraden In ◽  
Borin Peng ◽  
Senglong Pang ◽  
...  
Keyword(s):  
Zika Virus ◽  
Mammalian Cells ◽  
Vector Competence ◽  
Mosquito Species ◽  
Survival Rates ◽  
Transmission Efficiency ◽  
Phenotypic Differences ◽  
Local Risk

Since the epidemic in 2007, studies on vector competence for Zika virus (ZIKV) have intensified, showing that the transmission efficiency varies depending on the vector population, ZIKV strain, and dose of the infectious blood meal. In this study, we aimed to investigate the replication of African and Asian ZIKV strains in vitro and in vivo in order to reveal their phenotypic differences. In addition, we investigated the vector competence of Cambodian Aedes aegypti (Ae. aegypti) mosquitoes (urban and rural) for these ZIKV strains. We observed a significantly higher pathogenicity of the African ZIKV strain in vitro (in mosquito and mammalian cells), and in vivo in both Ae. aegypti and mice. Both mosquito populations were competent to transmit ZIKV as early as 7 days p.i., depending on the population and the ZIKV strain. Ae. aegypti from rural habitats showed significant higher transmission and survival rates than those from urban. We observed the highest transmission efficiency for the African ZIKV isolate (93.3% 14 days p.i.) and for the Cambodian ZIKV isolate (80% 14 days p.i.). Overall, our results highlight the phenotypic differences of the ZIKV lineages and the potential risk of ZIKV transmission by Ae. aegypti mosquitoes. Further investigations of Cambodian mosquito species and ZIKV specific surveillance in humans is necessary in order to improve the local risk assessment.

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