Efficient One-Pot Synthesis of 12-Aryl-8,9,10,12-Tetrahydrobenzo[a]Xanthen-11-one Derivatives Using NaHSO4 as Catalyst in Ionic Liquid

2010 ◽  
Vol 113-116 ◽  
pp. 1993-1996 ◽  
Author(s):  
Hong Jun Zang ◽  
Yong Zhang ◽  
Bo Wen Cheng
Keyword(s):  
Ionic Liquid ◽  
Reaction Time ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
Short Reaction Time ◽  
One Pot Synthesis ◽  
Three Component Coupling

A series of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives were synthesized via the three-component coupling from aromatic aldehydes, 2-naphthol and 5,5–dimethylcyclohexane -1,3-dione catalyzed by NaHSO4 in ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM]BF4). The reaction proceeded with good yields under short reaction time. The NaHSO4 was not expensive and the ionic liquid could be reused. The proposed method is efficient and environmentally friendly.

An Efficient and Simple One-Pot Synthesis of ?-Acetamido Ketones Catalyzed by Ytterbium Triflate in Ionic Liquid

2009 ◽  
Vol 62 (4) ◽  
pp. 322 ◽  
Author(s):  
Anil Kumar ◽  
M. Sudershan Rao ◽  
Israr Ahmad ◽  
Bharti Khungar
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Acetyl Chloride ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ytterbium Triflate ◽  
Three Component Coupling

Ytterbium triflate immobilized in the ionic liquid [bmim][BF4] catalyzes the three-component coupling of aromatic aldehydes, enolizable ketones, and acetonitrile in the presence of acetyl chloride at room temperature to afford β-acetamido ketones in good yields. The catalyst can be recovered and recycled for subsequent reactions without any appreciable loss of efficiency.

One-pot synthesis of 5-[1-substituted 4-acetyl-5-methyl-1H-pyrrol-2-yl)]-8-hydroxyquinolines using DABCO as green catalyst

2015 ◽  
Vol 21 (4) ◽  
pp. 207-210 ◽  
Author(s):  
Shawkat Ahmed Abdelmohsen ◽  
Yasser Abou-bakr El-Ossaily
Keyword(s):  
Reaction Time ◽  
Environmentally Friendly ◽  
Catalytic Amount ◽  
One Pot ◽  
Simple Method ◽  
Green Catalyst ◽  
Short Reaction Time ◽  
H Nmr ◽  
One Pot Synthesis ◽  
Substituted Pyrroles

AbstractA green and simple method for the synthesis of the title compounds 4 by the reaction of 5-chloroacetyl-8-hydroxyquinoline (1), pentane-2,4-dione (2), and amines 3 in the presence of a catalytic amount of 1,4-diazabicyclo[2.2.2]octane at 60°C is described. The procedure is amenable for the synthesis of other substituted pyrroles. Short reaction time, environmentally friendly procedure, and excellent yields are the main advantages. The structures of products 4a–n were characterized by 1H NMR, IR, and MS spectra.

scholarly journals An efficient green synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives via Strecker reaction under controlled microwave heating

2019 ◽  
Vol 8 (1) ◽  
pp. 297-301 ◽  
Author(s):  
Kamal Usef Sadek ◽  
Afaf Mohamed Abdel-Hameed ◽  
Hisham A. Abdelnabi ◽  
Yasser Meleigy
Keyword(s):  
Reaction Time ◽  
Green Synthesis ◽  
Microwave Heating ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
Short Reaction Time ◽  
Strecker Reaction ◽  
Benzoyl Cyanide ◽  
High Yields

Abstract A highly efficient multi-component one-pot synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives has been developed through the reaction of easily available aromatic aldehydes, benzoyl cyanide and either 2-aminoimidazole-4,5-dicarbonitrile or 3-amino-1,2,4-triazole in pyridine under controlled microwave heating. The process is environmentally friendly, is operationally simple, with short reaction time and with high yields.

PhI(OAc)2-Mediated One-Pot Synthesis of Benzoxazinones from Anthranilic Acids and Aromatic Aldehydes

2012 ◽  
Vol 36 (3) ◽  
pp. 123-126 ◽  
Author(s):  
Yuanyuan Xie ◽  
Suping Wang
Keyword(s):  
Reaction Time ◽  
Schiff Bases ◽  
Aromatic Aldehyde ◽  
Anthranilic Acid ◽  
Aromatic Aldehydes ◽  
Reaction Conditions ◽  
One Pot ◽  
Short Reaction Time ◽  
One Pot Synthesis ◽  
Anthranilic Acids

A novel way to synthesise 2-aryl-4H-benzo[d][1,3]oxazin-4-ones has been developed by the cyclisation of Schiff bases with (diacetoxyiodo)benzene. The salient features of this new protocol which starts from an anthranilic acid and an aromatic aldehyde, are short reaction time, mild reaction conditions and good yields.

scholarly journals Synthesis of tetrazolo[1,5-a]pyrimidine-6-carbonitriles using HMTA-BAIL@MIL-101(Cr) as a superior heterogeneous catalyst

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mohammad Hossein Abdollahi-Basir ◽  
Boshra Mirhosseini-Eshkevari ◽  
Farzad Zamani ◽  
Mohammad Ali Ghasemzadeh
Keyword(s):  
Ionic Liquid ◽  
Catalytic Activity ◽  
Reaction Time ◽  
Metal Organic Framework ◽  
One Pot ◽  
Short Reaction Time ◽  
Three Component Reaction ◽  
Metal Organic ◽  
Ft Ir ◽  
Novel Catalyst

AbstractA one-pot three component reaction of benzaldehydes, 1H-tetrazole-5-amine, and 3-cyanoacetyl indole in the presence of a new hexamethylenetetramine-based ionic liquid/MIL-101(Cr) metal–organic framework as a recyclable catalyst was explored. This novel catalyst, which was fully characterized by XRD, FE-SEM, EDX, FT-IR, TGA, BET, and TEM exhibited outstanding catalytic activity for the preparation of a range of pharmaceutically important tetrazolo[1,5-a]pyrimidine-6-carbonitriles with good to excellent yields in short reaction time.

scholarly journals Microwave Assisted One Pot Synthesis of 3,4-Dihydropyrano[c]chromene Derivatives using [Emim]OH Ionic Liquid as Novel Catalyst

2019 ◽  
Vol 31 (4) ◽  
pp. 829-833
Author(s):  
D.S. Bhagat ◽  
S.G. Pande ◽  
M.V. Katariya ◽  
R.P. Pawar ◽  
P.S. Kendrekar
Keyword(s):  
Ionic Liquid ◽  
Reaction Time ◽  
High Yield ◽  
Reaction Conditions ◽  
One Pot ◽  
Short Reaction Time ◽  
Aryl Aldehydes ◽  
Microwave Assisted ◽  
Novel Catalyst ◽  
Work Up

One-pot efficient protocol to the synthesis of 2-amino-5-oxo-4,5-dihydropyrano(3,2-c)chromene-3-carbonitrile derivatives via condensation of various aryl aldehydes, dicyanomethane and 4-hydroxycoumarin in presence of Emim hydroxide as an excellent homogeneous liquid catalyst. The key advantages of this methodology are mild reaction conditions, novel catalyst, short reaction time, eco-friendly, easy work-up procedure and high yield of isolation of derivatives.

scholarly journals Highly efficient, one-pot synthesis of novel bis-spirooxindoles with skeletal diversity via sequential multi-component reaction in PEG-400 as a biodegradable solvent

RSC Advances ◽  
2017 ◽  
Vol 7 (63) ◽  
pp. 39502-39511 ◽  
Author(s):  
Ensieh Safari ◽  
Ammar Maryamabadi ◽  
Alireza Hasaninejad
Keyword(s):  
Reaction Time ◽  
One Pot ◽  
Short Reaction Time ◽  
Peg 400 ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Skeletal Diversity

A green, efficient, multi-component protocol has been developed for synthesis of novel bis-spirooxindoles in short reaction time, easy workup and excellent yields.

Protic pyridinium ionic liquid: As an efficient, green and environmentally friendly catalyst for the one-pot synthesis of amidoalkyl naphthol derivatives

2014 ◽  
Vol 17 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahmood Tajbakhsh ◽  
Mohammad Norouzi ◽  
Saeed Baghery ◽  
Maryam Akbari
Keyword(s):  
Ionic Liquid ◽  
Environmentally Friendly ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Naphthol Derivatives ◽  
Amidoalkyl Naphthol
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