The Use of Rapid Prototyping to Fabricate Liver Tissue Engineering Scaffold

2011 ◽  
Vol 328-330 ◽  
pp. 658-661
Author(s):  
Singare Sekou ◽  
Shou Yan Zhong ◽  
Zhen Zhong Sun
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Glycolic Acid ◽  
Tissue Engineering Scaffold ◽  
Liver Tissue Engineering ◽  
Biodegradable Poly ◽  
Future Direction ◽  
Silicone Mould ◽  
Printing Machine

In this papers, the authors described a rapid prototyping method to produce vascularized tissue such liver scaffold for tissue engineering applications. A scaffold with interconnected channel was designed using CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable poly (L-lactic-co-glycolic acid) (PLGA )material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.

A Method to Fabricate Liver Tissue Engineering Scaffold

2011 ◽  
Vol 11 ◽  
pp. 73-80 ◽  
Author(s):  
S. Singare ◽  
Shou Yan Zhong ◽  
Zhen Zhong Sun
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Tissue Engineering Scaffold ◽  
Biodegradable Material ◽  
Scaffold Fabrication ◽  
Liver Tissue Engineering ◽  
Future Direction ◽  
Silicone Mould ◽  
Printing Machine

In this paper, the authors describe a rapid prototyping method to produce vascularized tissue such as liver scaffold for tissue engineering applications. A scaffold with an interconnected channel was designed using a CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.

scholarly journals Strontium ranelate-loaded PLGA porous microspheres enhancing the osteogenesis of MC3T3-E1 cells

RSC Advances ◽  
2017 ◽  
Vol 7 (40) ◽  
pp. 24607-24615 ◽  
Author(s):  
Zhenyang Mao ◽  
Zhiwei Fang ◽  
Yunqi Yang ◽  
Xuan Chen ◽  
Yugang Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Strontium Ranelate ◽  
Glycolic Acid ◽  
Tissue Engineering Scaffold ◽  
Porous Microspheres ◽  
Biodegradable Poly

Biodegradable poly lactic-co-glycolic acid (PLGA) has been used as a tissue engineering scaffold as well as a carrier for the delivery of proteins, drugs, and other macromolecules.

scholarly journals Fabrication 3d Tissue Engineering Scaffold Poly(Ethylene) Diacrylate Filled with Aramid Nanofiber: Mechanical Evaluation and Toxicity

2019 ◽  
Vol 8 (12) ◽  
pp. 1997-2006
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
3D Structure ◽  
Tissue Engineering Scaffold ◽  
Digital Light Processing ◽  
Technical Requirements ◽  
Preliminary Study ◽  
Poly Ethylene ◽  
3D Printing Technique ◽  
Selection Of

The selection of the optimum scaffold fabrication method becomes challenging due to a variety of manufacturing methods, existing biomaterials and technical requirements. Although, Digital light processing (DLP) 3D printing process is one of the SLA techniques which commonly used to fabricate tissue engineering scaffold, however, there is no report published on the fabrication of tissue engineering scaffold-based PEGDA filled with Aramid Nanofiber (ANFs). Hence, the feasible parameter setting for fabricating this material using DLP technique is currently unknown. This work aims to establish the feasible setting parameter via DLP 3D printing to fabricate PEGDA/ANFs 3D tissue engineering scaffold. Preliminary study has been done to identify the accurate composition and curing time setting in producing scaffold. In this work, the researcher has proved the potential and capability of these novel composition biomaterial PEGDA/ANFs to be print via DLP-3D printing technique to form a 3D structure which is not yet been established and has not reported elsewhere.

scholarly journals Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2529 ◽  
Author(s):  
Gabriela Štumberger ◽  
Boštjan Vihar
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Xanthan Gum ◽  
Vascular Grafts ◽  
Microfluidic Devices ◽  
Simple Method ◽  
New Approach ◽  
Hydrogel Matrix ◽  
Printing Method

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatine slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

Fabrication and characterization of electrospinning/3D printing bone tissue engineering scaffold

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 110557-110565 ◽  
Author(s):  
Yinxian Yu ◽  
Sha Hua ◽  
Mengkai Yang ◽  
Zeze Fu ◽  
Songsong Teng ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
3D Printing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Composite Scaffold ◽  
Tissue Engineering Scaffold ◽  
Fabrication And Characterization

A composite scaffold was fabricated with a method involving both electrospinning and 3D printing to give microscale pores and good mechanical properties. Biocompatibility and cell infiltration on the scaffold was evaluated by an in vitro study.

Sign in / Sign up

Export Citation Format

Share Document