Nanophotonic Rigid Contact Lenses: Engineering and Characterization

2013 ◽  
Vol 633 ◽  
pp. 239-252
Author(s):  
Đuro Koruga ◽  
Dragomir Stamenković ◽  
Ivan Djuricic ◽  
Ivana Mileusnic ◽  
Jovana Šakota ◽  
...  

Contact lenses are a common optical aid to provide help with refractive anomalies of the human eye. Construction of contact lenses is a complex engineering task as it requires knowledge of optics, materials science, production and characterization methods for product quality. Besides correcting refractive anomalies, by using contact lenses it is possible to change the characteristics of light through the manipulation of material structure properties. Nanomaterials, such as fullerene C60, are candidates for the medium that interacts with light, thus changing its properties. During material syntheses for contact lenses, fullerenes are added to the base material and optical characteristics of the new nanophotonic material are compared with the base material. The engineering, manufacture and characterization of both a commercial and a new nanophotonic contact lens is presented in this paper. The interaction of water with both base and nanophotonic contact lens materials is described. Using experimental techniques, the phenomena of an exclusion zone (EZ) is also identified.

Materials ◽  
2019 ◽  
Vol 12 (2) ◽  
pp. 261 ◽  
Author(s):  
Christopher Stephen Andrew Musgrave ◽  
Fengzhou Fang

More is demanded from ophthalmic treatments using contact lenses, which are currently used by over 125 million people around the world. Improving the material of contact lenses (CLs) is a now rapidly evolving discipline. These materials are developing alongside the advances made in related biomaterials for applications such as drug delivery. Contact lens materials are typically based on polymer- or silicone-hydrogel, with additional manufacturing technologies employed to produce the final lens. These processes are simply not enough to meet the increasing demands from CLs and the ever-increasing number of contact lens (CL) users. This review provides an advanced perspective on contact lens materials, with an emphasis on materials science employed in developing new CLs. The future trends for CL materials are to graft, incapsulate, or modify the classic CL material structure to provide new or improved functionality. In this paper, we discuss some of the fundamental material properties, present an outlook from related emerging biomaterials, and provide viewpoints of precision manufacturing in CL development.


2018 ◽  
Vol 2 (2) ◽  
pp. e14-e21
Author(s):  
Melissa Barnett ◽  
Jonathon Ross ◽  
Blythe Durbin-Johnson

Abstract Objectives: The purpose of this study was to evaluate the performance (i.e. vision, comfort and fit) of spherical and front-surface toric scleral lenses in subjects with regular, healthy corneas. Methods: Scleral lenses were fitin the eyes (n = 16) of healthy subjects (n = 9) with regular corneas, absent of pathology, and studied using an observational, multi-visit design. Lens fit was objectively evaluatedby an experienced practitioner.Following 1 month of successful lens wear, participants completedsubjective satisfaction surveys regarding the scleral lens wearing experience. Results:  According to participant surveys, scleral lenses were subjectively preferred over soft toric or gas permeable contact lenses in 88% of eyes, including in all eyes fit with a front-surface toric scleral lens (n = 3). Seventy-five percent (75%) of eyes achieved visual acuity of 0.1 logMAR or better, while all eyes with prior spectacle wear achieved visual acuity with a scleral lens within 1 Snellen line of spectacle correction. Seventy-five percent (75%) of eyes achieved good subjective comfort with a scleral lens. No participants reported poor subjective vision and/or comfort. Conclusions:  Our findings suggest that subjects preferred the performance of a scleral lens (spherical or front-surface toric) compared to a soft toric or gas permeable contact lens. Moreover, scleral lenses may provide a viable, alternative contact lens modality option for patients considering discontinuation of traditional soft toric and/or rigid contact lens wear; so long as the factors associated with hypoxia remain minimized. Key Words:  scleral lens; scleral contact lens; front-surface toric scleral lens; lens performance; normal eyes; healthy eyes


Author(s):  
Roberto Soto-Negro

ABSTRACT We report the case of a 35-year-old woman diagnosed with keratoconus since she was 18 years old and wearer of corneal rigid contact lenses (CLs). We refitted the case with the fully scleral CL ICD16.5 (Paragon Vision Sciences) for obtaining not only a successful visual restoration, but also a comfortable wear. We initiated the fitting with the spherical model of the CL, but it failed due to instability of the lens. We confirmed the presence of a clear asymmetry in the anterior scleral geometry in both eyes by using the profilometer eye surface profiler (ESP, Eaglet Eye), with a difference between nasal and temporal sagittal heights of 470 and 170 μm in right and left eyes respectively. Although this profile suggested the need for the fitting of a CL with significant peripheral toricity, we followed the manufacturer's guidelines and performed a trial with a CL of moderate peripheral toricity (125 μm of difference between steep and flat meridian). The stability of the CL failed again and finally a CL with a peripheral toricity close to that measured with the profilometer was fitted. With this lens, good visual performance, lens stability, and comfort was obtained and maintained during a 1-year follow-up. This case suggests that fully scleral CLs fitting might be optimized with the use of corneo-scleral profilometers, minimizing potentially the number of trials. This potential benefit should be investigated further in future studies. How to cite this article Piñero DP, Soto-Negro R. Anterior Eye Profilometry-guided Scleral Contact Lens Fitting in Keratoconus. Int J Kerat Ect Cor Dis 2017;6(2):97-100.


2020 ◽  
Vol 79 (1) ◽  
Author(s):  
Shishka Rupnarain ◽  
Nomvelo Madlala ◽  
Ntokozo Memela ◽  
Simpiwe Ngcobo ◽  
Nonkazimulo Shabalala ◽  
...  

Background: Patients with keratoconus, which is a common corneal ectasia, often present to specialised clinics for management. Understanding the clinical characteristics of keratoconus patients can help improve knowledge of the presentation and management of this corneal ectasia and predict the needs of the clinic providing care for affected individuals.Aim: To describe the clinical characteristics of keratoconus patients attending the University of KwaZulu-Natal (UKZN) eye clinic.Setting: University of KwaZulu-Natal eye clinic.Methods: The study used a retrospective research design by reviewing the clinical record cards of patients attending the UKZN contact lens eye clinic over a 4-year period (January 2014 to December 2017). Data related to age, clinical characteristics and method of management of the keratoconus patients were extracted and analysed using descriptive statistics.Results: Just less than one-quarter of all patients (n = 1210) attending the UKZN contact lens eye clinic had keratoconus that was most often bilateral. The mean age at presentation was 25.2 ± 9.6 years with 74% of the sample being younger than 30 years. More than 90% (n = 419) of the sample reported refractive reasons as the primary reason for presenting to the clinic. The majority of the sample had severe keratoconus (n = 257) and rigid contact lenses were most commonly used for management of keratoconus patients.Conclusion: Keratoconus presents at an early age with a more severe grade and it is most commonly managed using rigid contact lenses. These findings should be considered for keratoconus screening, diagnosis and treatment programmes in KwaZulu-Natal.


2013 ◽  
Vol 67 (6) ◽  
pp. 861-870 ◽  
Author(s):  
Aleksandra Debeljkovic ◽  
Lidija Matija ◽  
Djuro Koruga

This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38) and nanophotonic materials (SL38-A) for soft contact lenses were obtained by radical polymerization of 2-hydroxyethyl methacrylate and 2-hydroxyethyl methacrylate and fullerene, which were derived by the technology in the production lab of the company Soleko (Milan, Italy). The materials were used for production of soft contact lenses in the company Optix (Belgrade, Serbia) for the purposes of this research. Fullerene was used due to its apsorption transmission characteristics in ultraviolet, visible and near infrared spectrum. For the purposes of material characterization for potential application as soft contact lenses, network parameters were calculated and SEM analysis of the materials was performed while the optical properties of the soft contact lenses were measured by a Rotlex device. The values of the diffusion exponent, n, close to 0.5 indicated Fick's kinetics corresponding to diffusion. The investigated hydrogels could be classified as nonporous hydrogels. With Rotlex device, values of optical power and map of defects were showed. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is identical to the nominal value while this was not the case for the basic lens. Also, the quality of the nanophotonic soft contact lens is better than the basic soft contact lens. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.


2016 ◽  
Vol 75 (1) ◽  
Author(s):  
Wayne D.H. Gillan

The advent of large-diameter rigid contact lenses (semi-scleral lenses) has necessitated renewed understanding of the concept of ‘the sag’ of a contact lens and/or cornea. This article reviews the concept of ‘the sag’ and how to calculate the sag for spherical and aspherical surfaces. Reviews of empirical studies investigating the sag of the eye are presented. Data for normal and keratoconic corneas for sags as measured with an Oculus Keratograph are also included. How to include empirical measurements obtained in practice, in the determination of a first-trial semi-scleral lens, is suggested.


2010 ◽  
Vol 69 (2) ◽  
Author(s):  
E. Chetty ◽  
W. D. H. Gillan

Keratometric behaviour is a multifaceted issue that many researchers have investigated for years. Many internal and external influences can have an effect on the cornea’s keratometric behaviour. This investigation forms a small part of a larger study that aims at determining the effects that rigid contact lenses might have on keratometric behaviour. This pilot study examined the keratometric behaviour of a single, mildly keratoconic cornea that was fitted with a polymethyl methacrylate (PMMA) contact lens. Sixty successive auto-keratometric measurements were taken immediately before and immediately after three hours of contact lens wear. The data obtained was transformed to dioptric power matrices and were analysed using multivariate statistical methods. This study showed that, at least in one keratoconic cornea, there appeared to be a statistically significant change in corneal curvature under the influence of a PMMA contact lens. The contact lens had also appeared to decrease variation in corneal curvature. There was no control study done on this eye therefore the effects of diurnal variation, if any, could not be established. (S Afr Optom 2010 69(2) 69-76)


2014 ◽  
Vol 73 (1) ◽  
Author(s):  
W. D.H. Gillan

Discomfort when wearing contact lenses, especially rigid contact lenses, is a common complaint amongst neophyte as well as experienced contact lens wearers. Wearing a piggy-back system of contact lenses has been shown to improve comfort and wearing time, especially in keratoconic subjects. Twenty two normal subjects wore a rigid lens or a piggy-back system of lenses for thirty minutes and after a thirty minute break swopped the mode of lens wear and wore the second modality for a thirty minute period. This study suggests that a piggy-back lens system provides improved comfort compared to wearing a rigid lens on its own. The order of lens wear might, however, influence the perceived comfort.


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