Hyaluronic Acid Production by Genetic Modified GRAS Strains

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.950.13 ◽

2014 ◽

Vol 950 ◽

pp. 13-17 ◽

Author(s):

Xiao Fang ◽

Rong Shuai Duan ◽

Hai Ying Yang ◽

Jing Feng Liu

Keyword(s):

Escherichia Coli ◽

Bacillus Subtilis ◽

Hyaluronic Acid ◽

Genetic Engineering ◽

Acid Production ◽

Research Area ◽

Microbial Fermentation ◽

Streptococcus Zooepidemicus ◽

Comprehensive Review ◽

Hyaluronic Acid Production

Hyaluronic acid is an important polysaccharide of various physiological functions. Nowadays, it is produced mainly through microbial fermentation of Streptococcus zooepidemicus. HA production in more safe and efficient genetic modified GRAS strains is a hot research area. Bacillus subtilis, Lactococcus lactis, Streptococcus thermophiles, Agrobacterium sp. , and some Escherichia coli strains, which were GRAS strains, had been selected for genetic engineering to express hyaluronic acid. Here, we provide a comprehensive review of HA production by these genetic modified GRAS strains.

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A serum-free medium for colony growth and hyaluronic acid production by Streptococcus zooepidemicus NJUST01

Applied Microbiology and Biotechnology ◽

10.1007/s00253-005-0253-x ◽

2005 ◽

Vol 72 (1) ◽

pp. 168-172 ◽

Author(s):

Jianfa Zhang ◽

Xia Ding ◽

Liuyan Yang ◽

Zhiming Kong

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Colony Growth ◽

Streptococcus Zooepidemicus ◽

Serum Free Medium ◽

Free Medium ◽

Hyaluronic Acid Production

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Fermentation process development for hyaluronic acid production by Streptococcus zooepidemicus ATCC 39920

Korean Journal of Chemical Engineering ◽

10.1007/s11814-009-0072-3 ◽

2009 ◽

Vol 26 (2) ◽

pp. 428-432 ◽

Author(s):

Shu-Jen Chen ◽

Jia-Ling Chen ◽

Wei-Chih Huang ◽

Hsin-Liang Chen

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Fermentation Process ◽

Process Development ◽

Streptococcus Zooepidemicus ◽

Hyaluronic Acid Production

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Cheese whey: A cost-effective alternative for hyaluronic acid production by Streptococcus zooepidemicus

Food Chemistry ◽

10.1016/j.foodchem.2015.11.062 ◽

2016 ◽

Vol 198 ◽

pp. 54-61 ◽

Author(s):

Isabel R. Amado ◽

José A. Vázquez ◽

Lorenzo Pastrana ◽

José A. Teixeira

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Cheese Whey ◽

Cost Effective ◽

Effective Alternative ◽

Streptococcus Zooepidemicus ◽

Cost Effective Alternative ◽

Hyaluronic Acid Production

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Optimization of medium components for hyaluronic acid production by Streptococcus zooepidemicus MTCC 3523 using a statistical approach

Carbohydrate Polymers ◽

10.1016/j.carbpol.2011.06.065 ◽

2011 ◽

Vol 86 (4) ◽

pp. 1573-1577 ◽

Author(s):

Kanchankumar P. Patil ◽

Kirtee K. Kamalja ◽

Bhushan L. Chaudhari

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Statistical Approach ◽

Streptococcus Zooepidemicus ◽

Medium Components ◽

Hyaluronic Acid Production

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Enhanced hyaluronic acid production by a two-stage culture strategy based on the modeling of batch and fed-batch cultivation of Streptococcus zooepidemicus

Bioresource Technology ◽

10.1016/j.biortech.2008.02.035 ◽

2008 ◽

Vol 99 (17) ◽

pp. 8532-8536 ◽

Author(s):

Long Liu ◽

Guocheng Du ◽

Jian Chen ◽

Miao Wang ◽

Jun Sun

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Batch Cultivation ◽

Streptococcus Zooepidemicus ◽

Fed Batch ◽

Two Stage ◽

Culture Strategy ◽

Fed Batch Cultivation ◽

Hyaluronic Acid Production ◽

Two Stage Culture

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Is hyaluronic acid production transcriptionally regulated? A transcriptional repressor gene deletion study in Streptococcus zooepidemicus

Applied Microbiology and Biotechnology ◽

10.1007/s00253-021-11481-x ◽

2021 ◽

Author(s):

Weixia Gao ◽

Xiaoliang Zhang ◽

Guangtong Zhang ◽

Meng Zuo ◽

Wei Cao ◽

...

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Gene Deletion ◽

Transcriptional Repressor ◽

Streptococcus Zooepidemicus ◽

Repressor Gene ◽

Hyaluronic Acid Production

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Kinetics of hyaluronic acid production by Streptococcus zooepidemicus considering the effect of glucose

Biochemical Engineering Journal ◽

10.1016/j.bej.2009.12.001 ◽

2010 ◽

Vol 49 (1) ◽

pp. 95-103 ◽

Author(s):

Mashitah Mat Don ◽

Noor Fazliani Shoparwe

Keyword(s):

Hyaluronic Acid ◽

Acid Production ◽

Streptococcus Zooepidemicus ◽

Effect Of Glucose ◽

Kinetics Of ◽

Hyaluronic Acid Production

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Sensitivity to Hydrogen Peroxide of Growth and Hyaluronic Acid Production by Streptococcus zooepidemicus ATCC 39920

Developments in Chemical Engineering and Mineral Processing ◽

10.1002/apj.5500130503 ◽

2008 ◽

Vol 13 (5-6) ◽

pp. 531-540 ◽

Author(s):

M.D. Mashitah ◽

H. Masitah ◽

K.B. Ramachandran

Keyword(s):

Hydrogen Peroxide ◽

Hyaluronic Acid ◽

Acid Production ◽

Streptococcus Zooepidemicus ◽

Hyaluronic Acid Production

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Cloning and expression of hyaluronan synthase (hasA) in recombinant Escherichia coli BL21 and its hyaluronic acid production in shake flask culture

Malaysian Journal of Microbiology ◽

10.21161/mjm.190444 ◽

2019 ◽

Author(s):

Lai, Z. W. ◽

Teo, C. H.

Keyword(s):

Escherichia Coli ◽

Hyaluronic Acid ◽

Acid Production ◽

Shake Flask ◽

Cloning And Expression ◽

Hyaluronan Synthase ◽

Shake Flask Culture ◽

Flask Culture ◽

Escherichia Coli Bl21 ◽

Hyaluronic Acid Production

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Application of a novel cavern volume controlled culture model to microbial hyaluronic acid production by batch culture of Streptococcus zooepidemicus

Biochemical Engineering Journal ◽

10.1016/j.bej.2009.09.002 ◽

2010 ◽

Vol 48 (2) ◽

pp. 141-147 ◽

Author(s):

Long Liu ◽

Miao Wang ◽

Jun Sun ◽

Guocheng Du ◽

Jian Chen

Keyword(s):

Hyaluronic Acid ◽

Batch Culture ◽

Acid Production ◽

Streptococcus Zooepidemicus ◽

Culture Model ◽

Volume Controlled ◽

Hyaluronic Acid Production

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