Vertebroplasty in Goat Model Using Macroporous Calcium Phosphate Cement (MCPC®)

2007 ◽  
Vol 361-363 ◽  
pp. 377-380
Author(s):  
Xavier Bourges ◽  
Serge Baroth ◽  
Eric Goyenvalle ◽  
Ronan Cognet ◽  
Françoise Moreau ◽  
...  

We performed vertebroplasty on goat model by injecting a new macroporous calcium phosphate cement MCPC®. The mechanical property of the cement is about 12MPa after 24 hours (compression test). The cement matrix is totally transformed into poorly crystallized apatite in 48 hours. This study demonstrates that MCPC cement was suitable and efficient for a spine application. Its injectability allows to be used in mini invasive surgery and its mechanical properties are compatible to support spine strength. In addition, a bone ingrowth onto the BCP granules occurred with time.

2008 ◽  
Vol 396-398 ◽  
pp. 245-248
Author(s):  
Xavier Bourges ◽  
Eric Aguado ◽  
Eric Goyenvalle ◽  
Serge Baroth ◽  
G. Daculsi

We have developed a novel macroporous calcium phosphate cement MCPC® that sets to poorly crystalline apatite after mixing the powder component with an aqueous solution and has interconnective macroporosity We performed cranioplasty on rat model by injecting the new macroporous calcium phosphate cement MCPC®. The mechanical property of the cement is about 12MPa after 24 hours (compression test). The cement matrix is totally transformed into poorly crystalline apatite in 48 hours. This study demonstrates that MCPC® cement was suitable and efficient for parietal bone reconstruction. Its injectability and moldability allows to be used in bone reconstruction surgery and its mechanical properties are compatible to support calvarial reconstruction. In addition, a bone ingrowth onto the BCP granules occurred on time.


2011 ◽  
Vol 46 (4) ◽  
pp. 273
Author(s):  
Ki-Dae Kwon ◽  
Jae-Suk Chang ◽  
Soo-Ho Lee ◽  
Dong-Ho Lee ◽  
Kang-Sik Lee ◽  
...  

Orthopedics ◽  
2014 ◽  
Vol 37 (10) ◽  
pp. e906-e910 ◽  
Author(s):  
Guangjun Liao ◽  
Dongxiu Sun ◽  
Jian Han ◽  
Jiangwei Tan

2013 ◽  
Vol 788 ◽  
pp. 119-126 ◽  
Author(s):  
Bin Chu ◽  
Jian Xiong ◽  
Ming Bo Wang ◽  
Xiao Li Li ◽  
Zhen Ding She

The solidification time of injectable bone cement should be fit for the clinical application. This research find out the effect of the amount of water-absorbent agent and water-retaining agent. The optimal ratio was be determined. The hydroxyapatite fibers with strontium were added into the CPC. The mechanical property, cytotoxicity test, SEM morphology, XRD and degradation performance in vitro were characterized, respectively. The results show the CPC had the solidification time of 12min when the ratio as below: β-TCP 55.5%, Ca (H2PO4)2H2O(MCPM)36%, MgHPO43H2O 5%, MgSO41%, Sodium pyrophosphate2.5%. The main components of solidify CPC were hydroxyapatite (HA) and dicalcium phosphate dihydrate (DCPD). The materials had a good Anti-collapsing performance and the degradation rate up to 16.72% after 9 weeks. The mechanical property of composite materials which combined with hydroxyapatite fibers with strontium has been improved, and the cell proliferation rate is also higher than common CPC. This study shows a potentially effective method to improve the mechanical property and the biological activity of calcium phosphate cement.


2002 ◽  
Vol 7 (5) ◽  
pp. 562-569 ◽  
Author(s):  
Hiroo Mizobuchi ◽  
Toshikazu Tani ◽  
Ryuichi Takemasa ◽  
Hiroshi Yamamoto ◽  
Hiroshi Sonobe

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