Comparative Analysis of Mitochondrial DNA by Using Nucleotide Genomic Signals

2010 ◽  
Vol 670 ◽  
pp. 507-516 ◽  
Author(s):  
Paul Dan Cristea ◽  
Rodica Tuduce
Keyword(s):  
Mitochondrial Dna ◽  
Comparative Analysis ◽  
Nucleotide Pair ◽  
Innovative Technique ◽  
Evolutionary Changes ◽  
Genomic Signals

The nucleotide imbalance, the nucleotide pair imbalance and the nucleotide path of mitochondrial Nucleotide Genomic Signals (mtNuGSs) for several taxa have been analyzed comparatively. Evolutionary changes of conservative segments, as well as individual mutations of hyper-variable segments have been identified. An innovative technique, based on reference-offset representation of sets of related signals has been used throughout the study.

scholarly journals Comparative analysis of mitochondrial DNA datasets indicates that Toxascaris leonina represents a species complex

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Yuan-Chun Jin ◽  
Xiang-Yong Li ◽  
Jin-Hui Liu ◽  
Xing-Quan Zhu ◽  
Guo-Hua Liu
Keyword(s):  
Mitochondrial Dna ◽  
Comparative Analysis ◽  
Species Complex ◽  
Toxascaris Leonina

scholarly journals MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity

2015 ◽  
Vol 44 (D1) ◽  
pp. D1262-D1265 ◽  
Author(s):  
Dmitri Toren ◽  
Thomer Barzilay ◽  
Robi Tacutu ◽  
Gilad Lehmann ◽  
Khachik K. Muradian ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Comparative Analysis ◽  
Special Focus

scholarly journals Mitochondrial DNA Point Mutation at Nucleotide Pair 3316 in a Japanese Family with Heterogeneous Phenotypes of Diabetes.

1998 ◽  
Vol 45 (5) ◽  
pp. 625-630 ◽  
Author(s):  
SHIGERU NAKANO ◽  
MASATAKA FUKUDA ◽  
FUMITAKE HOTTA ◽  
TOMOHIKO ITO ◽  
TAKASHI ISHII ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Point Mutation ◽  
Japanese Family ◽  
Nucleotide Pair

scholarly journals Comparative analysis of mitochondrial genomes in different species reveals the evolution of G-quadruplexes

2021 ◽  
Author(s):  
Hiroshi Sugiyama ◽  
Vinodh Sahayasheela ◽  
Zutao Yu ◽  
Ganesh Pandian
Keyword(s):  
Gene Expression ◽  
Mitochondrial Dna ◽  
Comparative Analysis ◽  
Lower Order ◽  
Genome Stability ◽  
Mitochondrial Genomes ◽  
Cellular Functions ◽  
Higher Eukaryotes ◽  
Heavy Strand ◽  
Light Strand

Abstract G-quadruplexes (G4s) are noncanonical structures that can form in the genomes of a range of organisms and are known to play various roles in cellular function. G4s can also form in mitochondrial DNA (mtDNA) because of their high guanine content, and these G4s may play roles in regulating gene expression, DNA replication, and genome stability. However, little is known regarding the evolution and dissemination of G4s in mitochondria. Here we analyzed the potential G4-forming sequences in mtDNA of 16 species from various families and demonstrated that the heavy strand of mtDNA of higher-order organisms contained higher levels of G4 regions than that of lower-order organisms. Analysis of the codons in the light strand revealed enrichment of guanine/cytosine-rich regions in higher eukaryotes and of adenine/thymidine-rich regions in lower-order organisms. Our study showed the diversity of G4s in species ranging from lower to higher orders. In particular, mammals such as humans, chimpanzees, and monkeys display a greater number of G4s than lower-order organisms. These potentially play a role in a range of cellular functions and assist in the evolution of higher organisms.

scholarly journals Comparative analysis of human DNA extraction methods and mitochondrial DNA HV1 and HV2 haplogroup determination

2020 ◽  
pp. 73-83
Author(s):  
Aleksandra Nikezić ◽  
Stefan Blagojević ◽  
Maja Ćupurdija ◽  
Nevena Planojević ◽  
Jovana Jovankić ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Comparative Analysis ◽  
Dna Extraction ◽  
Extraction Methods ◽  
Human Dna ◽  
Dna Extraction Methods
Sign in / Sign up

Export Citation Format

Share Document