scholarly journals An immunohistochemical study of the localization of α and β subunits of S-100 protein in normal human brains and brain tumors

1990 ◽  
Vol 102 (9-10) ◽  
pp. 1061-1074
Author(s):  
Takashi TAMIYA
1991 ◽  
Vol 81 (6) ◽  
pp. 657-663 ◽  
Author(s):  
K. Hayashi ◽  
Y. Hoshida ◽  
Y. Horie ◽  
K. Takahashi ◽  
K. Taguchi ◽  
...  

1983 ◽  
Vol 9 (3) ◽  
pp. 360-362 ◽  
Author(s):  
Joan Spiegel ◽  
Mehrdad Nadji ◽  
Neal S. Penneys

Author(s):  
Hamidreza Fattahian ◽  
Pejman Mortazavi ◽  
Hamidreza Moosavian ◽  
Hamid Mohyeddin ◽  
Roozbeh Moridpour

Accurate diagnostic approaches to differentiate peripheral nerve sheet tumours from others have not been firmly established. The aim of this case report was to diagnose neurofibroma using a combination of diagnostic imaging, histopathology and immunohistochemistry, which were applied to a canine neurofibroma arising in the left mandible. The tumour was surgically excised and examined histologically. Round or spindle cells, with elongated, dense and homogenous chromatin and pale cytoplasm typical of Schwann cells in an abundant fibromyxomatous stroma, with ruby collagen fibres were seen. Immunohistochemistry demonstrated that S-100 and vimentin were more than 70% positive. Neurofibroma may therefore be recognisable using markers such as S-100 and vimentin.


2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Kayo Kuyama ◽  
Sisilia Fusi Fifita ◽  
Masamichi Komiya ◽  
Yan Sun ◽  
Yoshiaki Akimoto ◽  
...  

The purpose of this study was to determine the clinicopathological and immunohistochemical features of lipoma/fibrolipoma with rare occasions as osseous and/or chondroid differentiation in the oral cavity. Two cases of the tumors, who presented with a painless, relatively hard mass on the oral mucosa, were studied. These were consisted of a well-circumscribed mass of fatty tissue with chondroid and significant fibrous component intermixed with the lobules of fat cells with chondroid and woven bone component, respectively. Immunohistochemical study revealed that peripheral spindle cells around chondroid tissue stained diffusely for S-100 & and Sox-9, though peripheral spindle cells around osteoid tissue only stained for RUNX-2. According to review of the literature, lipoma/fibrolipoma with osseous and/or chondroid differentiation was 18 cases. Also fibrolipoma with osseous and chondroid differentiation is the first to be reported here. These results indicated that the cartilage/bone is produced by differentiation of undifferentiated mesenchymal cells of stroma.


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