scholarly journals Cathepsin D expression in the tumor cells and juxta-tumoral stromal cells of T1 invasive ductal carcinoma, Nos

2005 ◽  
Vol 8 (1) ◽  
pp. 17
Author(s):  
Baik Hyeon Jo ◽  
Doy Il Kim ◽  
Won Hung Lee ◽  
Tae Jin Lee ◽  
Jae Hyung Yoo ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Invasive Ductal Carcinoma ◽  
Stromal Cells ◽  
Cathepsin D ◽  
Ductal Carcinoma

Cathepsin D Expression in Colorectal Adenocarcinomas and Adenomas

2002 ◽  
Vol 17 (3) ◽  
pp. 165-168 ◽  
Author(s):  
Y. Kanber ◽  
N.R. Demirbag ◽  
A.D. Sam ◽  
N. Aydin
Keyword(s):  
Tumor Cells ◽  
Stromal Cells ◽  
Cathepsin D ◽  
Staining Intensity ◽  
Tumor Stage ◽  
Important Indicator ◽  
High Stage ◽  
Significant Difference ◽  
Colorectal Adenocarcinomas

The aim of this study was to investigate the role of cathepsin D in colorectal cancer. For this purpose cathepsin D expression was evaluated by means of immunohistochemistry in stromal and tumor cells of 31 colorectal carcinomas and 29 adenomas. Cytoplasmic cathepsin D expression of tumor cells was present in 90.3% of the carcinoma cases and various degrees of stromal cell cathepsin D expression were present in all cases. In the adenomas, the epithelial cells and stromal cells expressed cathepsin D in 68.96% and 96.55% of cases, respectively. The staining intensity was always weaker in the adenomas. When the stromal and tumor cell cathepsin D expression in the adenocarcinoma and adenoma cases were compared, a statistically significant difference was observed in the staining of stromal cells. Furthermore, stromal cathepsin D expression in the adenocarcinomas was related to tumor stage when the carcinomas were divided into low and high stage. Cathepsin D expression in stromal cells may be an important indicator of poor prognosis in colorectal adenocarcinomas.

Cathepsin D in host stromal cells, but not in tumor cells, is associated with aggressive behavior in node-negative breast cancer

1996 ◽  
Vol 27 (9) ◽  
pp. 890-895 ◽  
Author(s):  
Mehrdad Nadji ◽  
Manuel Fresno ◽  
Mehdi Nassiri ◽  
Gregory Conner ◽  
Agustin Herrero ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Aggressive Behavior ◽  
Tumor Cells ◽  
Stromal Cells ◽  
Cathepsin D ◽  
Node Negative ◽  
Node Negative Breast Cancer

Ultrasonographic findings of 46 resected cases with invasive ductal carcinoma of the pancreas within 20 mm in size

Choonpa Igaku ◽  
2018 ◽  
Vol 45 (3) ◽  
pp. 301-309 ◽  
Author(s):  
Sachiko KOBAYASHI ◽  
Shigeyuki HASUO ◽  
Motoi MIYAKOSHI ◽  
Tomohiro NAKATANI ◽  
Yukie NAKAJIMA ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Pancreas

Expression of Let-7c in invasive ductal carcinoma of breast cancer and its clinical significance

2009 ◽  
Vol 29 (4) ◽  
pp. 400-403
Author(s):  
Shu-rong SHEN ◽  
Jun-yi SHI ◽  
Xian SHEN ◽  
Guan-li HUANG ◽  
Xiang-yang XUE
Keyword(s):  
Breast Cancer ◽  
Clinical Significance ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma
Sign in / Sign up

Export Citation Format

Share Document