scholarly journals The UDP-Glucose Receptor P2RY14 Triggers Innate Mucosal Immunity in the Female Reproductive Tract by Inducing IL-8

2009 ◽  
Vol 182 (11) ◽  
pp. 7074-7084 ◽  
Author(s):  
Toru Arase ◽  
Hiroshi Uchida ◽  
Takashi Kajitani ◽  
Masanori Ono ◽  
Kayoko Tamaki ◽  
...  
Keyword(s):  
Mucosal Immunity ◽  
Reproductive Tract ◽  
Female Reproductive Tract

scholarly journals Mucosal Immunity in HIV/SIV Infection: T Cells, B Cells and Beyond

2019 ◽  
Vol 15 (1) ◽  
pp. 63-75 ◽  
Author(s):  
Barbara L. Shacklett
Keyword(s):  
T Cells ◽  
Mucosal Immunity ◽  
Reproductive Tract ◽  
Cell Types ◽  
Female Reproductive Tract ◽  
Multiparameter Flow Cytometry ◽  
Mucosal Tissues ◽  
New Information ◽  
Innate Lymphocytes ◽  
Hiv 1

As our understanding of mucosal immunity increases, it is becoming clear that the host response to HIV-1 is more complex and nuanced than originally believed. The mucosal landscape is populated with a variety of specialized cell types whose functions include combating infectious agents while preserving commensal microbiota, maintaining barrier integrity, and ensuring immune homeostasis. Advances in multiparameter flow cytometry, gene expression analysis and bioinformatics have allowed more detailed characterization of these cell types and their roles in host defense than was previously possible. This review provides an overview of existing literature on immunity to HIV-1 and SIVmac in mucosal tissues of the female reproductive tract and the gastrointestinal tract, focusing on major effector cell populations and briefly summarizing new information on tissue-resident memory T cells, Treg, Th17, Th22 and innate lymphocytes (ILC), subsets that have been studied primarily in the gastrointestinal mucosa.

Mucosal Immunity in the Human Female Reproductive Tract

2005 ◽  
pp. 1631-1646 ◽  
Author(s):  
William H. Kutteh ◽  
Jiri Mestecky ◽  
Charles R. Wira
Keyword(s):  
Mucosal Immunity ◽  
Reproductive Tract ◽  
Female Reproductive Tract ◽  
Human Female
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