scholarly journals Hashimoto’s encephalopathy in a patient with septal panniculitis: a case report

Reumatismo ◽  
2018 ◽  
Vol 70 (4) ◽  
pp. 268-269
Author(s):  
C. Cosso ◽  
M. Ghio ◽  
M. Cutolo
Keyword(s):  
Case Report ◽  
Autoimmune Thyroiditis ◽  
Behavioral Changes ◽  
Glucocorticoid Therapy ◽  
Thyroid Antibodies ◽  
Mental Confusion ◽  
Hashimoto’S Encephalopathy

Hashimoto’s encephalopathy (HE) is an autoimmune form of encephalopathy, associated with autoimmune thyroiditis. Its prevalence is estimated to be 2:100,000. HE is characterized by behavioral changes, mental confusion, dysarthria, ataxia, psychosis, paranoia, convulsions, hallucinations, headache and hyperthermia. Elevated thyroid antibodies are necessary for diagnosis and the disease responds dramatically to glucocorticoid therapy. We describe a patient with HE and panniculitis, an association reported twice in the literature.

scholarly journals Hashimoto's Encephalopathy Masquerading as Rapidly Progressive Dementia and Extrapyramidal Failure

2022 ◽  
Author(s):  
Yasser Aladdin ◽  
Bader Shirah
Keyword(s):  
Autoimmune Thyroiditis ◽  
Delayed Diagnosis ◽  
Thyroid Antibodies ◽  
Cerebral Damage ◽  
Serological Testing ◽  
Progressive Dementia ◽  
Rare Presentation ◽  
Hashimoto’S Encephalopathy ◽  
Immune Mediated ◽  
Underlying Pathogenesis

AbstractHashimoto's encephalopathy is a rare immune-mediated disorder characterized by subacute encephalopathy with elevated thyroid antibodies. Hashimoto's encephalopathy is also known as steroid-responsive encephalopathy associated with autoimmune thyroiditis. We report a rare presentation of Hashimoto's encephalopathy presenting with acute neuropsychiatric disturbances, rapidly progressive dementia, seizures, and extrapyramidal failure. Neuroimaging revealed multifocal vasculitides of major cerebral vessels that support the autoimmune vasculitic theory as the underlying pathogenesis for Hashimoto's encephalopathy. Unfortunately, permanent irreversible cerebral damage has already ensued before her presentation to our center, which rendered steroid therapy ineffective. Serological testing for Hashimoto's thyroiditis must be in the investigation of all rapidly progressive dementias as early diagnosis and timely management of autoimmune thyroiditis may salvage sizable and eloquent cerebral tissues. The rarity of the condition should not preclude the investigation of Hashimoto's disease even in the presence of normal levels of thyroid hormones. Delayed diagnosis may result in irreversibly catastrophic encephalopathy in patients who once presented with potentially curable dementia.

scholarly journals Infectious disease or Hashimoto's encephalopathy flares: A case report

Seizure ◽  
2011 ◽  
Vol 20 (9) ◽  
pp. 717-719 ◽  
Author(s):  
Wenyan Huang ◽  
Chang Xia ◽  
Marie Chatham
Keyword(s):  
Infectious Disease ◽  
Case Report ◽  
Hashimoto’S Encephalopathy

scholarly journals Paroxysmal Amnesia Attacks due to Hashimoto’s Encephalopathy

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Pelin Nar Senol ◽  
Aylin Bican Demir ◽  
Ibrahim Bora ◽  
Mustafa Bakar
Keyword(s):  
Cognitive Impairment ◽  
Antiepileptic Drug ◽  
Rare Disease ◽  
Psychiatric Symptoms ◽  
Thyroid Antibodies ◽  
Immunomodulatory Agents ◽  
Clinical Appearance ◽  
Hashimoto’S Encephalopathy ◽  
Eeg Abnormalities ◽  
Cerebral Involvement

Hashimoto’s encephalopathy is a rare disease which is thought to be autoimmune and steroid responsive. The syndrome is characterized by cognitive impairment, encephalopathy, psychiatric symptoms, and seizures associated with increased level of anti-thyroid antibodies. The exact pathophysiology underlying cerebral involvement is still lesser known. Although symptoms suggest a nonlesional encephalopathy in most of the cases, sometimes the clinical appearance can be subtle and may not respond to immunosuppressants or immunomodulatory agents. Here we report a case who presented with drowsiness and amnestic complaints associated with paroxysmal electroencephalography (EEG) abnormalities which could be treated only with an antiepileptic drug.

scholarly journals Hashimoto’s Encephalopathy Presenting with Unusual Behavioural Disturbances in an Adolescent Girl

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Murugan Selvaraj Karthik ◽  
Kulothungan Nandhini ◽  
Viswanath Subashini ◽  
Ramasamy Balakrishnan
Keyword(s):  
Clinical Presentation ◽  
Autoimmune Disorder ◽  
High Serum ◽  
Thyroid Antibodies ◽  
Antipsychotic Medications ◽  
Hashimoto’S Encephalopathy ◽  
Neuropsychiatric Manifestations ◽  
Euthyroid Status ◽  
Very High

Hashimoto’s encephalopathy (HE) is a rare autoimmune disorder with neurological and neuropsychiatric manifestations and elevated titres of anti-thyroid antibodies. Here we are reporting a case of HE in a 19-year-old girl who presented with seizure-like episodes, confusion, and behavioural disturbances with catatonic symptoms such as posturing, echopraxia, echolalia, and ambivalence. Patient did not respond to antipsychotics and anticonvulsants. On further investigation, patient was found to have high serum anti-TPO antibodies of about 1261 U/mL with euthyroid status, which supported a suspicion of HE. Our consultant neurologist confirmed the diagnosis and she was started on injection of methylprednisolone 750 mg OD. Since patient started showing clinical improvement, her antipsychotic medications were tapered off. On follow-up, patient has recovered and is functioning well. Since HE is a diagnosis of exclusion, very high anti-TPO antibodies and good response to steroids supported the diagnosis of HE in this patient after excluding other etiological possibilities. This case has been reported because the clinical presentation was predominantly neurobehavioural manifestations which is uncommon with HE.

Multiple autoimmunity, type 1 diabetes (T1DM), autoimmune thyroiditis and thyroid cancer: is there an association? A case report and literature review

2014 ◽  
Vol 27 (9-10) ◽  
Author(s):  
Kyriaki Karavanaki ◽  
Christina Karayianni ◽  
Ioannis Vassiliou ◽  
Marinella Tzanela ◽  
Triantafyllia Sdogou ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Thyroid Cancer ◽  
Case Report ◽  
Literature Review ◽  
Autoimmune Thyroiditis

scholarly journals Dyke-Davidoff-Masson-Syndrome Manifested by seizures and learning difficulties: A Case Report

2013 ◽  
Vol 5 (2) ◽  
pp. 111-113
Author(s):  
Mohammad Ibrahim Khalil ◽  
Maliha Hakim ◽  
Afzal Momin ◽  
Abu Nayeem ◽  
Md. Mohitul Islam ◽  
...  
Keyword(s):  
Case Report ◽  
Learning Difficulties ◽  
Facial Asymmetry ◽  
Behavioral Changes ◽  
Clinical Feature ◽  
Present Case Report ◽  
Cerebral Hemiatrophy ◽  
Generalized Seizures ◽  
Spastic Hemiplegia ◽  
Magnetic Resonance Imaging Mri

Dyke-Davidoff-Masson Syndrome (DDMS), also known as cerebral hemiatrophy, is a rare clinical condition characterized by seizures, facial asymmetry, contralateral spastic hemiplegia or hemiparesis, with learning difficulties and behavioral changes. It is commonly diagnosed in presence of clinical feature associated radiological findings which include cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses. In this present case report a 12 year old teenager female patient was diagnosed as DDMS with recurrent generalized seizures, learning difficulties and right sided hemiparesis. Magnetic resonance imaging (MRI) of the brain showed hemiatrophy involving the left cerebral hemisphere and EEG showed generalized epileptiform discharged. An X-ray of the paranasal air sinuses was normal.DOI: http://dx.doi.org/10.3329/jssmc.v5i2.20768J Shaheed Suhrawardy Med Coll 2013;5(2):111-113

scholarly journals Normocytic Normochromic Anemia Revealed an Early Onset Hashimoto’s Hypothyroidism in an Infant: A Case Report

2021 ◽  
pp. 1-5
Author(s):  
Manal Mustafa Khadora ◽  
Maysa Saleh ◽  
Rawah Idres ◽  
Sura Ahmed Al-Doory ◽  
Mahmoud Ahmed Radaideh
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Autoimmune Thyroiditis ◽  
Subclinical Hypothyroidism ◽  
Early Onset ◽  
Clinical Presentation ◽  
Primary Hypothyroidism ◽  
Normocytic Normochromic Anemia ◽  
Wide Range ◽  
Normochromic Anemia

Autoimmune thyroiditis is very rare etiology of primary hypothyroidism in infancy. Hypothyroidism has a wide range of clinical presentation, from subclinical hypothyroidism to overt type. It is unclear what pathological mechanisms connect thyroid function and erythropoiesis or how thyroid disease can contribute to anemia. We report a 12-month-old infant who presented with anemia associated with early onset of overt autoimmune thyroiditis. The peculiarity of our case enables us to draw attention of physician to consider acquired hypothyroidism in the differential diagnosis of unexplained anemia even if the neonatal screening is normal and congenital hypothyroidism is a remote possibility.

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