scholarly journals Kikuchi-Fujimoto Disease in the United States: Three Case Reports and Review of the Literature

2013 ◽  
Vol 6 (1) ◽  
pp. e2014001 ◽  
Author(s):  
Darcie M Deaver ◽  
Mojdeh Naghashpour ◽  
Lubomir Sokol

Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a benign, self-limiting disease that manifests primarily as cervical lymphadenopathy but may include low-grade fever, headache, and fatigue.  There is a higher incidence of KFD in women aged 20-35 years and in Asian populations.  A PubMed search revealed 590 articles that described KFD.  Of these, 22 cases have been fully described in the United States.  Ten of the 22 (45%) patients were male and 12 (55%) were female, with 20% Caucasian, 20% Asian American, and the remaining 60% of other ethnic backgrounds.  In this study, we describe an additional 3 cases of KFD and discuss the diagnosis, pathology, and management of KFD.

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Charissa Y. Chang ◽  
Juan C. Hernandez-Prera ◽  
Sasan Roayaie ◽  
Myron Schwartz ◽  
Swan N. Thung

Hepatocellular adenoma (HCA) is a benign neoplasm arising from hepatocytes. There is evidence that the inflammatory subtype may be associated with obesity and alcohol use and that men with metabolic syndrome may be at risk for malignant transformation of HCA. We sought to explore the combined experience of US centers as reported in the literature to document the epidemiologic shift in risk factors for HCA formation in the United States, namely, a shift from oral contraceptive pills (OCPs) to an emerging role of obesity as a contributing factor.Methods. Publications reporting HCA in the United States were identified through a PubMed search and a review of the literature. We excluded publications prior to 1970, single case reports, and publications for which there was no data available regarding patient characteristics including OCP use and the number of adenomas.Conclusion. Whereas earlier reports of HCA in the United States described cases exclusively in women exposed to OCPs, there is a trend towards an increase in HCAs reported in men, HCAs in the absence of OCP use, and increased reporting of multiple HCAs. This may be a result of newer OCP formulations and increasing prevalence of obesity.


Author(s):  
Asha Nadkarni

Asian American literature has capaciously explored the issues of gender, sexuality, and reproduction that have been so foundational to Asian American racial formation. It has likewise engaged, directly or indirectly, with “eugenics,” a pseudoscience by which nation states sought to improve their populations through managing reproduction. Eugenics, a term coined by Charles Darwin’s cousin Sir Francis Galton in 1883, spans the late 19th to the early 21st centuries, where it continues in the form of population control and the “new” eugenics of genetic and reproductive technologies. In some national sites eugenics was aligned with feminist movements for birth control, whereas in others, such as the United States, they were largely opposed. Nonetheless, eugenic feminists argued that women’s right reproduction was the necessary mechanism by which women should gain rights within the state; as a formation, moreover, eugenic feminism specifically targeted Asian American women as standing in the way of US feminist advance. As such, one of the key ways eugenics was practiced in the United States in relationship to Asian populations was through immigration policy. The history of Asian exclusion in the United States therefore speaks to a larger eugenic project predicated on the notion that Asian immigrants embodied a public health threat in terms of diseases and deviant sexualities of various sorts. The 1965 Immigration and Naturalization Act opened up Asian immigration to the United States and also gave rise to a new set of stereotypes, gendered and otherwise, about Asian Americans as model minorities. Asian American literature has critically mined these issues, with some Asian American literature acceding to eugenics by stressing an assimilationist politics and with other works challenging it by critiquing eugenics’ reproductive logic of purity.


PEDIATRICS ◽  
1996 ◽  
Vol 98 (1) ◽  
pp. 130-133 ◽  
Author(s):  
Jason S. Debley ◽  
David J. Rozansky ◽  
Michael L. Miller ◽  
Ben Z. Katz ◽  
Marianne E. Greene

Histiocytic necrotizing lymphadenitis, also known as Kikuchi-Fujimoto disease, is a disorder of lymph nodes originally described by Kikuchi1 and Fujimoto2 in 1972. Since 1982 this disorder has been increasingly recognized in the United States and worldwide, with the most extensive analyses of the disease presented by Dorfman et al.3-5 There has been little discussion of this entity in the pediatric literature. The most common presentation of necrotizing lymphadenitis includes fever and painless cervical lymphadenopathy. Patients may also present with weight loss, nausea, vomiting, diarrhea, chills, or diaphoresis. On occasion, myalgias, arthralgias, malar or butterfly rash, hepatomegaly, and splenomegaly have been noted.3


2020 ◽  
Author(s):  
Zhaoying Xian ◽  
Anshul Saxena ◽  
Zulqarnain Javed ◽  
John E. Jordan ◽  
Safa Alkarawi ◽  
...  

AbstractObjectivesTo evaluate COVID-19 infection and mortality in ethnic and racial sub-groups across all states in the United States.MethodsPublicly available data from “The COVID Tracking Project at The Atlantic” was accessed between 09/09/2020 and 09/14/2020. For each state and the District of Columbia, % infection, % death, % population proportion for subgroups of race (African American (AA), Asian, American Indian or Alaska Native, (AI/AN) and White), and ethnicity (Hispanic/Latino, and non-Hispanic), were recorded. Absolute and relative excess infection (AEI and REI) and mortality (AEM and REM) were computed as absolute and relative difference between % infection or % mortality and % population proportion for each state. Median (IQR) REI is provided below.ResultsThe Hispanic population had a median of 158% higher COVID-19 infection relative to their % population proportion (median REI 158%, [IQR: 100% to 200%]). This was followed by AA, with 50% higher COVID-19 infection relative to their % population proportion (median REI, 50% [IQR 25% to 100%]). The AA population had the most disproportionate mortality with a median of 46% higher mortality than % population proportion, (median REM 46% [IQR, 18% to 66%]). Disproportionate impact of COVID-19 was also seen in AI/AN and Asian population with ≥100% excess infections than % population proportion seen in 35 states for Hispanic, 14 states for AA, 9 states for AIAN, and 7 states for Asian populations. There was no disproportionate impact in the white population in any state.ConclusionsRacial/ethnic minorities (AA, Hispanic, AIAN and Asian populations) are disproportionately affected by COVID 19 infection and mortality across the nation. These findings underscore the potential role of social determinants of health in explaining the disparate impact of SARS-CoV-2 on vulnerable demographic groups, as well as the opportunity to improve outcomes in chronically marginalized populations.


2007 ◽  
Vol 5 (1) ◽  
pp. 12-32
Author(s):  
ShiPu Wang

This essay delineates the issues concerning AAPI art exhibitions from a curator’s perspective, particularly in response to the changing racial demographics and economics of the past decades. A discussion of practical, curatorial problems offers the reader an overview of the obstacles and reasons behind the lack of exhibitions of AAPI works in the United States. It is the author’s hope that by understanding the challenges particular to AAPI exhibitions, community leaders, and patrons will direct future financial support to appropriate museum operations, which in turn will encourage more exhibitions and research of the important artistic contribution of AAPI artists to American art.


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