scholarly journals Fungal Infection in Patients with Diabetes Mellitus

2017 ◽  
Vol 18 (1) ◽  
pp. 20 ◽  
Author(s):  
Na Ra Yun
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infection ◽  
Patients With Diabetes

scholarly journals Mucormycosis in diabetes mellitus

2012 ◽  
Vol 1 (2) ◽  
pp. 73-75 ◽  
Author(s):  
Prashant Khatiwada ◽  
Aditi Giri ◽  
Prasana Khatiwoda
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infection ◽  
Pulmonary Infection ◽  
Fungal Spores ◽  
Multifaceted Approach ◽  
Patients With Diabetes ◽  
Nose And Paranasal Sinuses ◽  
Anti Fungal ◽  
Lipid Formulations ◽  
Common Manifestation

Mucormycosis is an opportunistic fulminant fungal infection, which mainly infects immunocompromised patients. Infection with mucormycosis can cause devastating rhino-orbital-cerebral and pulmonary infection with an extremely poor prognosis. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. We report a case of mucormycosis in an uncontrolled diabetic patient to emphasize early diagnosis of this potentially fatal fungal infection. Rhino-orbitalcerebral mucormycosis is the most common manifestation in patients with diabetes mellitus. We also review the current concepts in management of mucormycosis. Mucormycosis remains difficult to treat and requires a multifaceted approach involving elimination of predisposing factors, surgical debridement, and anti-fungal therapy. Lipid formulations of Amphotericin B are the treatments of choice. DOI: http://dx.doi.org/10.3126/jaim.v1i2.6531 Journal of Advances in Internal Medicine 2012;01(02):73-75

scholarly journals Frequency and types of skin disorders and associated diabetes mellitus in elderly Jordanians

2021 ◽  
Vol 8 (4-5) ◽  
pp. 574-578
Author(s):  
F. Najdawi ◽  
M. Fa'ouri
Keyword(s):  
Diabetes Mellitus ◽  
Bacterial Infection ◽  
Fungal Infection ◽  
Skin Disorder ◽  
Skin Diseases ◽  
The Elderly ◽  
Skin Lesions ◽  
Skin Disorders ◽  
Patients With Diabetes ◽  
Considerable Morbidity

A retrospective study of 232 elderly patients seen between August 1998 and April 2000 at the skin clinic in Princess Haya hospital, Aqaba, was undertaken to determine the prevalence of skin disorders, and those most commonly associated with diabetes mellitus, in the elderly. Eczema/dermatitis was the commonest skin disorder seen [25.9% of cases], followed by pruritus without skin lesions [15.1%], viral infection [14.7%, most commonly herpes zoster], fungal infection [13.8%], and bacterial infection [10.3%]. Bacterial infection was the commonest skin disorder in patients with diabetes mellitus [62.5%], followed by fungal infection [50.0%]. Skin diseases cause considerable morbidity in elderly people; health promotion and education can do much to reduce the risks of these disorders in the elderly, especially those with diabetes

scholarly journals Three cases of mucoromycosis in patients with diabetes mellitus (Moscow region)

2004 ◽  
Vol 50 (5) ◽  
pp. 39-44
Author(s):  
A. V. Dreval' ◽  
V. A. Gubkina ◽  
T. S. Kamynina ◽  
V. A. Loseva ◽  
E. V. Mel'nikova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infection ◽  
Diagnostic Errors ◽  
General Term ◽  
Moscow Region ◽  
Northern Europe ◽  
Patients With Diabetes ◽  
The Mediterranean

Mucoromycosis is an aggressive fungal infection, the so-called phytomycosis is a general term for the spectrum of diseases caused by Mucorales class fungi [2]. Mucoromycosis is rare in Northern Europe (occasionally imported from the countries of the Mediterranean or America), which often leads to fatal diagnostic errors. In the last decade, cases of mucoromycosis have been reported in the Moscow region; our experience in treating this disease may prove useful to endocrinologists.

Intramuscular Nerve and Neuromuscular Junction Alteration In Extraocular Muscles of Diabetic Mice

1985 ◽  
Vol 43 ◽  
pp. 682-683
Author(s):  
Bruce R. Pachter
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Nerves ◽  
Sudden Onset ◽  
Extraocular Muscles ◽  
Diabetic Patients ◽  
Oculomotor Palsy ◽  
Third Nerve Palsy ◽  
Patients With Diabetes ◽  
Intramuscular Nerve ◽  
Oculomotor Nerves

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).

Desmopressin Stimulates Parallel Norepinephrine and Tissue Plasminogen Activator Release in Normal Subjects and Patients with Diabetes Mellitus

1988 ◽  
Vol 59 (02) ◽  
pp. 269-272 ◽  
Author(s):  
M B Grant ◽  
C Guay ◽  
R Lottenberg
Keyword(s):  
Diabetes Mellitus ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Time Course ◽  
Vascular Endothelial Cells ◽  
Normal Subjects ◽  
Plasma Norepinephrine ◽  
Endogenous Catecholamine ◽  
Tissue Plasminogen ◽  
Patients With Diabetes

SummaryDesmopressin acetate administration markedly stimulates release of tissue plasminogen activator (t-PA) from vascular endothelial cells. The mechanism for this effect is unknown. Because infusion of epinephrine has been shown to increase t-PA levels, we examined the role of endogenous catecholamine mediation of t-PA release by desmopressin. Intravenous desmopressin acetate (0.3 μg/kg) was infused over 30 min in 9 controls and 11 subjects with diabetes mellitus, a condition associated with abnormalities of the fibrinolytic system. Plasma was collected in the supine, overnight fasted state at 15 min intervals (0-60 min) for measurement of t-PA activity, t-PA antigen and fractionated catecholamines. t-PA activity peaked at 30-45 min and subsequently decreased. The norepinephrine levels paralleled the t-PA activity. t-PA activity increased 10-fold from 0.14 ± .12 to 1.49 ± 0.79 IU/ml (Mean ± SD) and plasma norepinephrine increased 2- fold from 426 ± 90 to 780 ± 292 pg/ml. However, epinephrine and dopamine levels did not change significantly. The response to desmopressin of control and diabetic subjects was not shown to differ and their data were combined. We conclude that desmopressin increases plasma norepinephrine in addition to t-PA and that the parallel time course of change suggests a possible role for norepinephrine in mediating endothelial cell t-PA release.

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