Suspected avocado (Persea americana) poisoning in goats

1991 ◽  
Vol 62 (4) ◽  
pp. 186-188 ◽  
Author(s):  
P. Stadler ◽  
I. B.J. Van Rensburg ◽  
T. W. Naudé
Keyword(s):  
Clinical Findings ◽  
Persea Americana ◽  
Lung Oedema ◽  
Histopathological Findings ◽  
Myocardial Degeneration ◽  
Severe Lung

A herd of 15 Cameroon goats was suspected of having" been poisoned by eating leaves of the Fuerte variety of avocado pear (Persea americana). Two of the affected goats were examined clinically, while necropsies were carried out on 3 of the 4 that had died. The most significant clinical findings were tachycardia, hyperpnoea and evidence of lung oedema. At necropsy severe lung oedema, hydrothorax and hydropericardium were present. Severe myocardial degeneration, necrosis and fibrosis were the major histopathological findings.

scholarly journals High-resolution computed tomography and histopathological findings in hypersensitivity pneumonitis: a pictorial essay

2016 ◽  
Vol 49 (2) ◽  
pp. 112-116 ◽  
Author(s):  
Pedro Paulo Teixeira e Silva Torres ◽  
Marise Amaral Rebouças Moreira ◽  
Daniela Graner Schuwartz Tannus Silva ◽  
Roberta Rodrigues Monteiro da Gama ◽  
Denis Masashi Sugita ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lung Biopsy ◽  
Hypersensitivity Pneumonitis ◽  
Giant Cells ◽  
Clinical Findings ◽  
High Resolution Computed Tomography ◽  
Histopathological Findings ◽  
Pictorial Essay ◽  
Inflammatory Infiltrates

Abstract Hypersensitivity pneumonitis is a diffuse interstitial and granulomatous lung disease caused by the inhalation of any one of a number of antigens. The objective of this study was to illustrate the spectrum of abnormalities in high-resolution computed tomography and histopathological findings related to hypersensitivity pneumonitis. We retrospectively evaluated patients who had been diagnosed with hypersensitivity pneumonitis (on the basis of clinical-radiological or clinical-radiological-pathological correlations) and had undergone lung biopsy. Hypersensitivity pneumonitis is clinically divided into acute, subacute, and chronic forms; high-resolution computed tomography findings correlate with the time of exposure; and the two occasionally overlap. In the subacute form, centrilobular micronodules, ground-glass opacities, and air trapping are characteristic high-resolution computed tomography findings, whereas histopathology shows lymphocytic inflammatory infiltrates, bronchiolitis, variable degrees of organizing pneumonia, and giant cells. In the chronic form, high-resolution computed tomography shows traction bronchiectasis, honeycombing, and lung fibrosis, the last also being seen in the biopsy sample. A definitive diagnosis of hypersensitivity pneumonitis can be made only through a multidisciplinary approach, by correlating clinical findings, exposure history, high-resolution computed tomography findings, and lung biopsy findings.

scholarly journals Analysis of intraoperative findings with clinico-pathological features in appendicitis-an observational study

2021 ◽  
Vol 9 (1) ◽  
pp. 96
Author(s):  
Kumar Lakshman ◽  
Shilpashree Channasandra Shekar ◽  
Naveen Narayan ◽  
Suhas NarayanaSwamy Gowda ◽  
Veena Ghanteppagol ◽  
...  
Keyword(s):  
Observational Study ◽  
Categorical Data ◽  
Scoring Systems ◽  
Inflammatory Cells ◽  
Clinical Findings ◽  
Study Data ◽  
Chronic Appendicitis ◽  
Histopathological Findings ◽  
Suspected Appendicitis ◽  
Operative Findings

Background: Appendectomy is the most common abdominal surgery performed today. Appendicitis consists of vast spectrum ranging from acute to chronic to recurrent forms however existence of recurrent and chronic appendicitis is still doubted by many. In spite of various scoring systems and appendectomy being the ultimate treatment, its timing remains still controversial especially in chronic and recurrent variants of appendicitis.Methods: A total of 100 consecutive cases of suspected appendicitis who were admitted investigated and treated at our centre were taken up for this observational study. Data pertaining to clinical, operative and histopathological findings were collected and tabulated. Mean and SD were used for continuous data and for categorical data, frequency and percentages were calculated. A chi-square test was used for categorical data to find statistical significance.Results: Per operatively the appendix appeared non-inflamed in 57% of patients suggestive of chronic (recurrent) form and inflamed in 43% of patients suggestive of an acute form of appendicitis. The histopathological studies revealed chronic inflammatory cells in 63% of the resected specimens, suggestive of chronic appendicitis and acute inflammatory cells in 37% of the specimens, suggestive of acute appendicitis.Conclusions: We conclude that the correlation of clinical findings, operative findings and the histopathological findings correlate with one another (p<0.001). The surgeon’s clinical and operative findings have specificity of around 87.30% and 90.47% respectively. Hence the diagnostic accuracy of the surgeon is directly dependent on the surgeons’ expertise and there is no substitution for an experienced surgeon’s judgement.

IgG4-related disease: a case report

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Silvia de las Heras Flórez ◽  
Mercedes Carretero Pérez ◽  
Carmen Teresa Sanz Díaz ◽  
José Alejandro Medina García
Keyword(s):  
Case Report ◽  
Elevated Serum ◽  
Symptomatic Patient ◽  
Clinical Findings ◽  
The Body ◽  
Histopathological Findings ◽  
Related Disease ◽  
Igg4 Related Disease ◽  
Serum Igg4

AbstractIgG4-related disease (IgG4-RD) is a condition that was first described recently, and is capable of affecting any organ of the body. Diagnosis is based on the correlation of clinical findings with histopathological findings and elevated serum IgG4. Treatment involves corticosteroids and rituximab for the most severe cases. We report the case of a symptomatic patient diagnosed of IgG4-RD whose diagnosed was guided by elevated serum IgG4 levels.

Histopathological Findings of Intraoral Pleomorphic Adenomas: A Retrospective Study of a Case Series

2019 ◽  
Vol 27 (7) ◽  
pp. 729-735 ◽  
Author(s):  
Maria Eduarda Pérez-de-Oliveira ◽  
Augusto César Leal da Silva Leonel ◽  
Jurema Freire Lisboa de Castro ◽  
Elaine Judite de Amorim Carvalho ◽  
Pablo Agustin Vargas ◽  
...  
Keyword(s):  
Case Series ◽  
Myoepithelial Cells ◽  
Clinical Findings ◽  
Clinicopathological Features ◽  
Significance Level ◽  
Exact Test ◽  
Histopathological Findings ◽  
Pleomorphic Adenomas ◽  
Microscopic Features ◽  
Hematoxylin And Eosin

The aim of this study was to describe the clinicopathological features of 21 cases of intraoral pleomorphic adenoma (PA), with emphasis on histopathological findings. Between 2000 and 2016, all patients diagnosed as intraoral PA were retrieved and histopathological slides stained with hematoxylin and eosin reviewed to confirm the diagnosis. All tumors were classified histologically according to Seifert et al (1980). The clinical and histopathological variables were analyzed using the Fisher’s exact test, considering a significance level of 5% ( P < .05). Plasmacytoid (85.7%), spindle (38.1%), and epithelioid (9.5%) myoepithelial cells were observed. Oncocytic (47.6%) and mucous (19%) cells were also found. The stroma was predominantly fibrous (95.2%), followed by myxoid (66.7%), hyaline (61.9%), and chondromyxoid (33.3%). Squamous (57.1%), adipose (47.6%), sebaceous (14.3%), and bone (14.3%) differentiations were found. Additionally, a group of tumors presented pleomorphism (23.8%), mitoses (14.3%), capsule infiltration (9.5%), and necrosis. The presence of cystic structures occurred significantly in patients older than 30 years ( P = .04) and mitoses were more observed in PA from buccal mucosa ( P = .026). All cases that presented plasmacytoid cells were smaller than 1.5 cm ( P = .015). All tumors with up to 50% stroma area presented with size smaller than 2.0 cm ( P = .013). Intraoral PA presents a large morphological spectrum and several microscopic features are associated with clinical findings.

scholarly journals Histopathological Findings in Uterus and Cervix of Hysterectomy Specimens

2015 ◽  
Vol 2 (1) ◽  
pp. 26
Author(s):  
Harshal A. Patil ◽  
Archana Patil ◽  
Suresh V. Mahajan
Keyword(s):  
Uterine Fibroid ◽  
Cervical Dysplasia ◽  
Operative Management ◽  
Clinical Findings ◽  
Physiological Changes ◽  
Clinicopathological Correlation ◽  
Female Reproductive System ◽  
Histopathological Findings ◽  
Pathological Correlation ◽  
The Subject

<strong>Background:</strong> For centuries, the female reproductive system has been affected by various abnormalities and diseases and hence has been the subject of interest and the basis for the gynaecological practice. The uterus being a vital reproductive and hormone-responsive organ, is subjected to a variety of physiological changes and benign and malignant disorders. <strong>Aims and Objectives:</strong> To study the indications of hysterectomy, to study gross and histopathological features of uterus and cervix in hysterectomy specimens and correlate with clinical findings. <strong>Material and Methods:</strong> This was a descriptive study of the gross and histopathological findings of uterus and cervix in 150 hysterectomy specimens received in the department. The hysterectomy specimens received were fixed in 10% formalin for 24 hours, were examined grossly and necessary sections were obtained. The tissue pieces were then processed in automated tissue processor, well labelled paraffin blocks were made. Approximately 2-3μ thickness sections were cut with the help of microtome and were stained routinely by Hematoxylin &amp; Eosin stain and special stains like PAS or other were used wherever necessary. The histopathological findings of uterus and cervix were noted and these findings were then correlated with clinical diagnosis. <strong>Results:</strong> Overall clinicopathological correlation was noted in all 150 cases. In cases of uterine fibroid it was 69.7% and 100% in case of endometrial carcinoma and cervical dysplasia. Most common pathology found was uterine leiomyomas in 48 cases and next to it was adenomyosis in 30 cases. <strong>Conclusion:</strong> It can be concluded that clinico-pathological correlation in case of endometrial cancer and uterine fibroid is excellent, but in case of DUB and prolapse uterus it varies. This signifies the importance of clinico-pathological correlation in all cases of hysterectomy to improve the clinical outcome and post-operative management.

scholarly journals Ashy Dermatosis and Lichen Planus Pigmentosus: The Histopathological Differences

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Suthinee Rutnin ◽  
Siriorn Udompanich ◽  
Nathathai Pratumchart ◽  
Sarawin Harnchoowong ◽  
Vasanop Vachiramon
Keyword(s):  
Lichen Planus ◽  
Cell Layer ◽  
Clinical History ◽  
Clinical Findings ◽  
Electronic Records ◽  
Histopathological Diagnosis ◽  
Limited Data ◽  
Histopathological Findings ◽  
Global Consensus ◽  
Clinical Presentations

Background. Ashy dermatosis (AD) and lichen planus pigmentosus (LPP) are both acquired macular pigmentation of uncertain aetiology. Despite the controversy surrounding their entities, recent global consensus has concluded that they are 2 different diseases with distinct clinical presentations. Nevertheless, there are limited data on their histopathological comparisons. Objective. To evaluate the differences in histopathological findings between AD and LPP. Methods. Electronic records and photographs of patients with the diagnosis of AD or LPP from January 2008 to December 2018 were retrospectively reviewed by a dermatologist. Patients were then classified into groups with AD and LPP, based on the clinical descriptions from the recent consensus. Those with history/clinical presentations suggestive of other causes of macular pigmentation were excluded. The histopathological diagnosis of AD and LPP was then reevaluated by a blinded dermatopathologist. Results. One hundred and twenty-four patients with acquired macular pigmentation were identified; 24 were excluded due to clinical history or photographs being inconsistent with AD or LPP. Of the remaining 100 patients, 71 had clinical findings consistent with LPP while 29 had AD. The prevalence of epidermal hyperkeratosis was significantly higher in LPP when compared to AD (33.8% vs. 0%, p<0.001), as well as epidermal hypergranulosis (35.2% vs. 0%, p<0.001), lichenoid dermatitis (49.3% vs. 7.1%, p<0.001), perifollicular infiltration (47.9% vs.10.3%, p<0.001), and perifollicular fibrosis (35.2% vs. 10.3%, p=0.01). In addition, the degree of pigmentary incontinence was more severe in LPP (21.1% vs. 3.5%, p=0.015). For AD, vacuolization of the epidermal basal cell layer was more common (96.4% vs. 77.5%, p=0.02). Conclusions. Although most cases of AD and LPP can be diagnosed clinically, in doubtful cases, histopathological findings of lichenoid dermatitis, epidermal hyperkeratosis/hypergranulosis, and moderate to severe pigmentary incontinence can help distinguish LPP from AD.

Ultrastructure of the lesion induced by toxin T-514 isolated from K. humboldtiana in the alveolar region of the lung

1992 ◽  
Vol 50 (1) ◽  
pp. 640-641
Author(s):  
Julio Sepúlveda-Saavedra ◽  
Beatriz González-Corona ◽  
Víctor A. Tamez Rodríguez ◽  
Ma. Victoria Bermúdez de Rocha ◽  
Alfredo Piñeyro López
Keyword(s):  
Electron Microscope ◽  
Guinea Pig ◽  
Macaca Fascicularis ◽  
Osmium Tetroxide ◽  
Lead Citrate ◽  
Severe Damage ◽  
Thin Sections ◽  
Alveolar Region ◽  
Histopathological Findings

It has been shown in previous studies that the toxin T-514 isolated from K. humboldtiana induces severe damage to the lung in treated rodents. Histopathological findings include edema, and alveolar hemorrage. However, the ultraestructure of the lesion has not been investigated. In this study we used two species of rodents: Hamster and guinea pig, and a primate: Macaca fascicularis. Animals received different single dosis of the toxin via intraperitoneal. Control animals received only the vehicle (propylen glycol). Inmediately after spontaneous death, lung samples were fixed in Karnovsky-Ito fixative, post fixed in osmium tetroxide and embedded in epon. Thin sections were prepared with an Ultratome V LKB, stained with uranly acetate and lead citrate, and studied in an electron microscope Zeiss-EM109.

Clinical Findings with SAL Audiometry: Some Further Observations

1965 ◽  
Vol 30 (4) ◽  
pp. 325-335
Author(s):  
George E. Lynn ◽  
Jack A. Willeford
Keyword(s):  
Clinical Findings
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