scholarly journals Glaucoma: a brief update for 2017

2017 ◽  
Vol 59 (6) ◽  
pp. 5-10 ◽  
Author(s):  
Natalie Schellack ◽  
Gustav Schellack ◽  
Selente Bezuidenhout ◽  
Lucille Malan ◽  
Hanneke De Klerk
Keyword(s):  
South Africa ◽  
Risk Factor ◽  
Visual Field ◽  
Pharmacological Treatment ◽  
Treatment Options ◽  
Visual Field Loss ◽  
Modifiable Risk Factor ◽  
Rational Use ◽  
Intra Ocular Pressure ◽  
Ocular Pressure

Glaucoma is a complex condition of the eye and the second leading cause of blindness around the globe. It is an ophthalmic neurodegenerative condition and is characterised by a raised intra-ocular pressure (IOP). The latter also constitutes the only modifiable risk factor in glaucoma management. When left untreated patients may gradually experience a visual field loss, and even lose their sight completely. This article provides a brief overview of this condition, the pharmacological treatment options that are available in South Africa, as well as the rational use thereof.

Severe Myopia as a Risk Factor for Progressive Visual Field Loss in Primary Open-Angle Glaucoma

1997 ◽  
Vol 211 (2) ◽  
pp. 66-71 ◽  
Author(s):  
Etsuo Chihara ◽  
X. NIL ◽  
Jin Dong ◽  
Yasuyuki Takashima ◽  
Masayuki Akimoto ◽  
...  
Keyword(s):  
Risk Factor ◽  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Open Angle

Intraocular pressure as a risk factor for visual field loss in pseudoexfoliative and in primary open-angle glaucoma

Ophthalmology ◽  
1998 ◽  
Vol 105 (12) ◽  
pp. 2225-2230 ◽  
Author(s):  
Miguel A Teus ◽  
Miguel A Castejón ◽  
Miguel A Calvo ◽  
Patricia Pérez—Salaı́ces ◽  
Ana Marcos
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Open Angle

Corneal thickness as a risk factor for visual field loss in patients with preperimetric glaucomatous optic neuropathy

2003 ◽  
Vol 136 (5) ◽  
pp. 805-813 ◽  
Author(s):  
Felipe A Medeiros ◽  
Pamela A Sample ◽  
Linda M Zangwill ◽  
Christopher Bowd ◽  
Makoto Aihara ◽  
...  
Keyword(s):  
Risk Factor ◽  
Visual Field ◽  
Optic Neuropathy ◽  
Corneal Thickness ◽  
Visual Field Loss ◽  
Glaucomatous Optic Neuropathy

Topical treatment of chronic simple glaucoma

1964 ◽  
Vol 2 (5) ◽  
pp. 18-19
Keyword(s):  
Visual Field ◽  
Topical Treatment ◽  
Aqueous Humour ◽  
Open Angle Glaucoma ◽  
Ciliary Muscle ◽  
Open Angle ◽  
Intra Ocular Pressure ◽  
Muscle Contract ◽  
Ocular Pressure

In chronic simple (open-angle) glaucoma loss of visual field may be prevented by improving the outflow of aqueous humour from the eye and thus lowering the raised intra-ocular pressure. This is achieved mainly by miotic drugs which constrict the pupil and make the ciliary muscle contract. These either mimic acetylcholine, acting directly on the ciliary muscle, or inhibit cholinesterase and so allow acetylcholine to accumulate.

scholarly journals The Effect of Ametropia on Glaucomatous Visual Field Loss

2021 ◽  
Vol 10 (13) ◽  
pp. 2796
Author(s):  
Eun Young Choi ◽  
Raymond C. S. Wong ◽  
Thuzar Thein ◽  
Louis R. Pasquale ◽  
Lucy Q. Shen ◽  
...  
Keyword(s):  
Risk Factor ◽  
Visual Field ◽  
Linear Regression ◽  
High Myopia ◽  
Visual Field Loss ◽  
Mean Deviation ◽  
Spherical Equivalent ◽  
Pattern Deviation ◽  
The Relationship ◽  
Loss Severity

Myopia has been discussed as a risk factor for glaucoma. In this study, we characterized the relationship between ametropia and patterns of visual field (VF) loss in glaucoma. Reliable automated VFs (SITA Standard 24-2) of 120,019 eyes from 70,495 patients were selected from five academic institutions. The pattern deviation (PD) at each VF location was modeled by linear regression with ametropia (defined as spherical equivalent (SE) starting from extreme high myopia), mean deviation (MD), and their interaction (SE × MD) as regressors. Myopia was associated with decreased PD at the paracentral and temporal VF locations, whereas hyperopia was associated with decreased PD at the Bjerrum and nasal step locations. The severity of VF loss modulated the effect of ametropia: with decreasing MD and SE, paracentral/nasal step regions became more depressed and Bjerrum/temporal regions less depressed. Increasing degree of myopia was positively correlated with VF depression at four central points, and the correlation became stronger with increasing VF loss severity. With worsening VF loss, myopes have increased VF depressions at the paracentral and nasal step regions, while hyperopes have increased depressions at the Bjerrum and temporal locations. Clinicians should be aware of these effects of ametropia when interpreting VF loss.

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