scholarly journals Pattern of pericardial diseases in HIV-positive patients at University College Hospital, Ibadan, Nigeria

2011 ◽  
Vol 12 (2) ◽  
pp. 25-26 ◽  
Author(s):  
Umar Abubakar ◽  
P O Adeoye ◽  
O A Adebo ◽  
V O Adegboye ◽  
E B Kesieme ◽  
...  

Rationale. Pericarditis has been reported as the most common cardiac complication of HIV disease, followed by pericardial effusion. Methods. A retrospective review was conducted of all 68 patients treated for pericardial diseases between August 2003 and July 2008 at University College Hospital, Ibadan, Nigeria. HIV-positive patients (N=42) were compared with those who were HIV negative (N=26). Results. More male than female patients presented with pericardial disease, and the HIV-positive patients were younger than those who were HIV negative. Pericardial effusion was the commonest mode of presentation, accounting for 20 HIV-positive patients (47.7%) and 13 HIV-negative patients (50%). Pericardiostomy was the commonest surgical intervention performed in HIV-positive patients (N=15), while the majority of HIV-negative patients had pericardiocentesis. Conclusion. Pericardial effusion was the commonest cardiac presentation in HIV-positive patients in our setting. We recommend that patients with pericardial effusion be investigated for HIV infection.

2015 ◽  
Vol 14 (3) ◽  
pp. 201-207
Author(s):  
Joshua.O. Akinyemi ◽  
Olubukola A. Adesina ◽  
Modupe.O. Kuti ◽  
Babatunde.O. Ogunbosi ◽  
Achiaka E. Irabor ◽  
...  

Author(s):  
Olutosin A. Awolude ◽  
Sunday O. Oyerinde

Background: Cervical precancer lesions, caused by persistence of human papilloma virus (HPV) infection, is common among women living with Human immunodeficiency virus (HIV) infection.  However, there remains paucity of information on these dysplastic lesions especially in low- and middle-income countries of the world as there are few programmes that have incorporated routine screening as a standard of care. Aim: To determine the pattern of precancer lesions of the cervix among treatment experienced HIV positive women in a large antiretroviral therapy programme in South West Nigeria. Study Design: Retrospective review of clinical records. Place and Duration of Study: HIV Programme in College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria between January 2014 and December 2015.  Methodology: A review of the Pap smear results of 468 women attending the antiretroviral therapy (ART) clinic at the University College Hospital (UCH) Ibadan over a 2-year period was done. The cytological results were analyzed with biosocial variables. Level of significance was set at 95% confidence level. Results: The mean age of the participants reviewed was 37.1+/- 8.7 years.  The mean duration of ART among the participants was 19.5 (±14.0) months. The prevalence of any form of squamous Intraepithelial lesions (SIL) varied from 10.0% among those on ART for up to 12 months to 1.4% among those with more than 18 months of ART use (p=022) and polygamous relationship is significantly associated with dysplastic cervical lesions among this studied  cohort (p=0.043) Conclusion: While ART appears to have anti-Human Papillomavirus (HPV) activities as observed in the pattern of cervical dysplastic lesions, polygamy, a common family setting in this environment seems to promote development of SIL among these WLHIV. These findings require further studies to corroborate in the light of limitations of difficulty in disaggregating the duration of HIV diagnosis from the onset of treatment as most were already on treatment before the screening and failure of baseline Pap smear test at the entry point to determine the rate of progression.


1996 ◽  
Vol 89 (7) ◽  
pp. 389-392 ◽  
Author(s):  
Gerond Lake-Bakaar ◽  
Roger Grimson

Our objective was to identify factors that might correlate with human immunodeficiency virus (HIV) disease stage in intravenous drug abusers (IVDA). Particular attention was given to alcohol abuse. We accordingly explored in a cross-sectional study the relation between stage of HIV disease and age, sex, needle sharing, ethnicity, self-reported history of alcohol consumption and CAGE scores. IVDA from a single municipal hospital were subdivided into three groups according to HIV disease status. Group 1 comprised 42 individuals with AIDS; group 2 comprised 114 who were HIV positive but without AIDS; and group 3 comprised 52 who were HIV negative. Information on alcohol consumption and CAGE responses were obtained by questionnaire and interview. Discriminant analysis indicated that alcohol abuse, assessed either by self-reported consumption or by CAGE scores, was significantly more common in the AIDS group than in either the HIV positive or the HIV negative groups, when controlled for age, sex, and needle sharing status. The relative risk of AIDS was 3.8 times higher in the heavy drinkers than in moderate drinkers. Needle sharing was also more common in the AIDS group than in the HIV positive or HIV negative groups when the other factors were controlled for. AIDS was more common in black than white IVDA, and this increased frequency did not appear related to alcohol consumption since the distribution of heavy drinkers within each category of HIV disease did not differ within the ethnic groups. These data indicate that a history of heavy alcohol consumption is more common in IVDA with AIDS than in IVDA at earlier stages of HIV disease.


2014 ◽  
Vol 13 (5) ◽  
pp. 697-704
Author(s):  
Helen N Obilor ◽  
Prisca O Adejumo ◽  
Rose E Ilesanmi

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 734-734
Author(s):  
Oluwatoyin Ajulo ◽  
Olusola Adetunji ◽  
Olugbenga Ajulo

Abstract Objectives To estimate the prevalence rate of cases of gastroenteritis caused by food poisoning reported to University College Hospital. Methods This was a retrospective observational study of patients who attended the clinic from 2010–2016. Patient's folders were surveyed for patients who had reported at the hospital with diarrhoeal cases. Relevant information such as types of food eating, causes and duration of diarrhea etc were retrieved from the folders. Results Data from past records of patients who had attended clinic from 2010–2016 at University College Hospital (UCH) for gastroenteritis as a result of food borne poisoning showed a total of 72 diarrhoeal cases of which 25 (76.9%) were caused by food poisoning. In Medical out-patient ward (MOP), there was only 24 cases of food poisoning out of the 34 cases of diarrhoea reported. MOP had the highest cases of diarrhoea (34) recorded while Surgical out-patient ward (SOP) had the lowest number of cases, just 3 cases. Children out-patient ward (CHOP) and SOP had no reported case of food poisoning while Ante-natal clinic ward (ANC) had only one case of reported food poisoning. The following foods were indicated in food poisoning such as rice, pop corn, kilichi and fried potatoes. Fish roll was indicated as the only source of food poisoning for all diarrhoeal cases reported at ANC. Augmentin, Metronidazole, Ciprofloxacin, Ceftriaxone, Loperamide, Normal saline and Coatem were the only drugs used in treatment. Conclusions The study indicated a relationship between the types of wards and drug used. Also, ciprofloxacin was the drug of choice used by all wards. Funding Sources Self-sponsored.


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