scholarly journals Evaluation of the adverse reactions of antiretroviral drug regimens in a tertiary care hospital

2013 ◽  
Vol 45 (2) ◽  
pp. 145 ◽  
Author(s):  
MuktaN Chowta ◽  
G. J. K Prakash Raju ◽  
Faheem Mubeen ◽  
ZahoorA Rather
Author(s):  
BHUVANESHWARI S ◽  
VIJAYA D

Objectives: This study was planned to study the association of ramipril and telmisartan with hyponatremia and to compare the hyponatremia effect of ramipril and telmisartan. Methods: The study was conducted in a tertiary care hospital. Serum sodium levels were assayed in patients taking ramipril and telmisartan. Fifty-one patients were recruited. The patient’s age, gender, drug dosage, and frequency of drug administration were collected using a pro forma. Statistical analysis of data was performed using SPSS version 23.0. Results: About 35.3% (28 out of 51) of the study population administered with ramipril and telmisartan developed hyponatremia. Predisposition to develop hyponatremia was high in males compared to females. Incidence of hyponatremia was 43.8% (7 out of 16) in the age group of 50–60 years. Although, incidence of hyponatremia was 56.5% (13 out of 23) in ramipril group compared to 17.9% (5 out of 28) in telmisartan group, it was not statistically significant. Conclusion: The current study laid emphasis on the requisite for monitoring of serum sodium level in patients on ramipril and telmisartan administration to avoid morbidity and mortality due to unexpected adverse reactions.


2020 ◽  
Vol 14 (1) ◽  
pp. 44 ◽  
Author(s):  
Prashant Agarwal ◽  
Archana Solanki ◽  
Rahul Katharia ◽  
Ashutosh Singh ◽  
Abhishek Chauhan ◽  
...  

Author(s):  
Dr. Rahul Rajvanshi ◽  
Dr. Farzana Kothari ◽  
Dr. Milind Dighe ◽  
Dr. Jhalak Patel

Background: Voluntary donors normally tolerate blood donation very well, but, occasionally, adverse reactions of variable severity may occur during or at the end of the collection. The occurrence of adverse reactions to blood donation significantly hampers donor retention and negatively impacts on the universal availability of adequate numbers of blood donor units.  Objective: To analyze the spectrum and prevalence of adverse reactions in blood donors in a tertiary care hospital-based blood bank in SSG Hospital, Vadodara.  Materials and Methods: The details of blood donors who presented for donation from January 2107 to April 2019 period were retrieved from the departmental archives for analysis. These included type of donor, type and frequency of adverse reactions to blood donation. Results: The prevalence of adverse reactions to blood donation was (315/35027) 0.9%; this occurred more frequently in first time donors compared to repeat blood donors. Presyncopal reactions were the most frequent adverse reaction encountered among the donors 52.38% (165/315). Conclusion: Presyncopal reactions are common adverse reactions in our blood donor set; this has implications on transfusion safety and blood donor retention. Keywords: Presyncopal reactions, adverse donor reactions, blood donor


Sign in / Sign up

Export Citation Format

Share Document