COMPARATIVE STUDY ON RAMIPRIL AND TELMISARTAN-ASSOCIATED HYPONATREMIA

2020 ◽  
pp. 162-164
Author(s):  
BHUVANESHWARI S ◽  
VIJAYA D
Keyword(s):  
Serum Sodium ◽  
Adverse Reactions ◽  
Serum Sodium Level ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Drug Dosage ◽  
Care Hospital ◽  
Age Group ◽  
Study Population ◽  
Pro Forma

Objectives: This study was planned to study the association of ramipril and telmisartan with hyponatremia and to compare the hyponatremia effect of ramipril and telmisartan. Methods: The study was conducted in a tertiary care hospital. Serum sodium levels were assayed in patients taking ramipril and telmisartan. Fifty-one patients were recruited. The patient’s age, gender, drug dosage, and frequency of drug administration were collected using a pro forma. Statistical analysis of data was performed using SPSS version 23.0. Results: About 35.3% (28 out of 51) of the study population administered with ramipril and telmisartan developed hyponatremia. Predisposition to develop hyponatremia was high in males compared to females. Incidence of hyponatremia was 43.8% (7 out of 16) in the age group of 50–60 years. Although, incidence of hyponatremia was 56.5% (13 out of 23) in ramipril group compared to 17.9% (5 out of 28) in telmisartan group, it was not statistically significant. Conclusion: The current study laid emphasis on the requisite for monitoring of serum sodium level in patients on ramipril and telmisartan administration to avoid morbidity and mortality due to unexpected adverse reactions.

scholarly journals Demographic profile and outcome analysis in paediatric intensive care unit at tertiary care hospital in the sub-Himalayan region

2020 ◽  
Vol 7 (9) ◽  
pp. 1897
Author(s):  
Nilay Ranjan Bagchi ◽  
Goutam Das ◽  
Aritra Guha
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Himalayan Region ◽  
Critically Ill Children ◽  
Outcome Analysis ◽  
Care Hospital ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Pro Forma ◽  
North Bengal

Background: Care of critically ill children continues to be one of the most challenging aspects of the field of paediatrics. Our study therefore, was done to see the demographic and morbidity pattern of the disease at a tertiary care hospital in the Sub Himalayan region and also the modifications that can lead to better outcomes.Methods: This was a retrospective record-based study which reviewed the admissions in to the PICU of tertiary care centre in the Sub Himalayan region of North Bengal for a period of 2 years (April 2018 to April 2020) with age group more than one month to twelve years of age from both medical and surgical sub-specialties. Data collected in pre-designed pro forma. Descriptive study analysis was done.Results: Out of the total 776 cases analysed 59% were male. LRTI comprised of maximum percentage of cases 27.8%, followed by sepsis (21.6%) and meningo encephalitis (16.7%). A maximum of 39% stayed for 3-7days in PICU, and 29.9% expired. Out of the total deaths, meningo encephalitis was responsible for maximum (27.6%).Conclusions: Our study is the first of its kind depicting the the demographic and morbidity patterns of the disease at a PICU in a tertiary care hospital in the Sub Himalayan region. Outcome analysis showed that PICU mortality rate was higher than in relevant recent studies. 

scholarly journals STATUS OF URINARY 15-F2t-ISOPROSTANE LEVELS IN GENERALIZED TONIC–CLONIC SEIZURE PATIENTS WITH LEVETIRACETAM IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 98-100
Author(s):  
BHUVANESHWARI S ◽  
VIJAYA D
Keyword(s):  
Tertiary Care Hospital ◽  
Meta Analysis ◽  
Tertiary Care ◽  
Age Groups ◽  
Clonic Seizure ◽  
Care Hospital ◽  
Age Group ◽  
Epileptic Patients ◽  
The Mean ◽  
Pro Forma

Objectives: The objective of the study was to analyze urinary 15-2t-isoprostane levels in epileptic patients with levetiracetam (LEV) and to compare the urinary 15-2t-isoprostane levels between the different age groups, smokers, and alcoholics. Methodology: The study was conducted in a tertiary care hospital. Urinary 15-2t-isoprostane levels were assayed in epileptic patients taking LEV. Twenty patients were recruited. Urinary levels of 15-F2t-isoprostane determined by ELISA. The patient’s age, gender, height, weight, smoking, and alcoholic history were collected using pro forma. Statistical analysis of data was performed using SPSS version 23.0. Results: A total of 20 participants recruited for the study. Among these, 70% were male and 30% were female. The mean weight and height were more in males compared to females. The mean 15-F2t-isoprostane level was significantly higher in males compared to females. More than 40% of the participants were in the age group of >40 years. However, the mean urinary 15-F2t-isoprostane level is higher in the age group of 19–30 years. Only 20% of the participants were smokers and alcoholics. Non-smokers and non-alcoholics had higher urinary 15-F2t-isoprostane levels compared to smokers and alcoholics. Conclusion: The urinary 15-F2t-isoprostane levels were more in males, the age group of 19–30 years, non-smokers and non-alcoholics. However, the levels are lesser when compared to earlier meta-analysis study. This concludes that LEV may have antioxidant effect. There is a need for further studies with more sample size and correlation of LEV and urinary 15-F2t-isoprostane levels.

scholarly journals A clinical and mycological study of dermatophytosis in a tertiary care hospital

2021 ◽  
Vol 7 (3) ◽  
pp. 429
Author(s):  
Rajesh Munuswamy ◽  
Pramodhini Subramanian
Keyword(s):  
Clinical Diagnosis ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Skin Lesions ◽  
Climatic Conditions ◽  
Fungal Culture ◽  
Care Hospital ◽  
Age Group ◽  
Male Preponderance ◽  
Study Population

<p class="abstract"><strong>Background:</strong> With changing climatic conditions, socio-demographic profile, economic conditions and occupational profile of the population, the profile of the dermatophyte infections is also changing. Hence, the study was done to find out the prevalence of various clinical pattern of dermatophytosis and correlate the clinical diagnosis with KOH positivity and fungal culture positivity.</p><p class="abstract"><strong>Methods:</strong> This prospective observational study was conducted in a tertiary care hospital, Puducherry. The study included patients presenting to the dermatology outpatient department with skin lesions suggestive of dermatophyte infections between January 2016 to July 2017. The KOH test and fungal culture were done.<strong></strong></p><p class="abstract"><strong>Results:</strong> The mean age of the patients was 33.65±11.61 years, with the majority belonging to 16 to 30 years of age group. There was a high male preponderance 72% with male:female ratio of 2.57:1. The most common clinical diagnosis was <em>Tinea corporis</em> in 47.50% of the population., followed by <em>Tinea Unguium</em> in 28% and <em>Tinea cruris</em> in 19.50%. KOH positivity was seen in 86 (43%) out of 200 cases in the study population. The culture was positive in 55 (27.50%) of the study population. The most common organism isolated in culture was <em>Trichophyton mentagrophyte</em> (10%), followed by <em>Trichophyton rubrum</em> (9.5%) and <em>Trichophyton tonsurans</em> (5.5%). 55 (27.5%) of the people had both culture and KOH positive.</p><p class="abstract"><strong>Conclusions:</strong> Dermatophyte infections commonly affect the young and economically productive age group of 16 to 30-year, with high male preponderance. KOH tends to show a higher proportion of positivity as compared to culture.</p>

scholarly journals Demographic profile and pathway to care in patients with schizophrenia in a tertiary care hospital from western Nepal

2017 ◽  
Vol 4 (1) ◽  
pp. 27-29
Author(s):  
M. Belbase ◽  
J. Adhikari ◽  
T.A. Khan ◽  
R.K. Jalan
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Care Hospital ◽  
Age Group ◽  
Medical College ◽  
Study Population ◽  
First Contact ◽  
Pathway To Care ◽  
Severe Mental Health Problem

Introduction: Schizophrenia is one of the severe mental health problem and its guarded treatment response and association with as the stigma makes it a chronic debilitating personal, family and social problem of all the psychiatric illness. Timely Identification and management of this condition is important as early diagnosis and management gives better treatment response.Methods: This is a descriptive study done in patients attending psychiatry OPD of Nepalgunj Medical College, Kohalpur for 12 months from June 2013 to May 2014.Results: Out of the 86 study subjects (n=86), males were 54 in number followed by 32 females. The most common age group was 21-40 years representing 46(53.4%), followed by 41-60 years 24(28%), <20 years 12(13.9%) and >60 years 4(4.7%). The most common first contact of the patient with schizophrenia was with faith healers 54 (62.8%) followed by consultation with psychiatrist 18(20.9%). Among the study population, 38(44.2%) visited to the psychiatrist after >41 weeks of the beginning of the illness followed by 34(39.5%) visited in <10 weeks of the beginning of the schizophrenia.Conclusions: Faith healers were the most common first contact person for the patients with schizophrenia followed by psychiatrist . Most of the schizophrenia patients come to psychiatrist after 40 weeks of their illness.

A Study on prescribing pattern of drugs in orthopaedic in-patient department at a tertiary care hospital in Guntur region

2020 ◽  
Vol 8 (2) ◽  
pp. 60-70
Author(s):  
Anjani Teja Ch ◽  
Ramesh babu K ◽  
Leela subramanyam S ◽  
Janani Y ◽  
Eswar Sai Kiran K ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Care Delivery ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Care Hospital ◽  
Age Group ◽  
Common Condition ◽  
Prescribing Pattern ◽  
Prescribing Indicators ◽  
Bed Days

The descriptive observational study was conducted over six months among inpatients of the orthopaedics department. The aim is to observe the prescribing pattern of drugs, to find out the percentage of analgesics given and most commonly prescribed analgesic, to compare the prescribed drugs whether they are in NLEM, WHO list and calculate DDD/100 Bed-days and to analyze the drugs for WHO prescribing drugs. A total of 250 patients were included in the study. Out of this, 168 were male, and 82 were female. Most of the patients were in the age group of 31-40[45 in number with 18%]. The most common condition was found to fracture [113 in number with 95.2%]. Commonly prescribed drugs were analgesics 447 with 26.76%. Among all the NSAID's, PCM was most commonly prescribed analgesic with 34.4%. The highest no, of drugs was found to be 4drugs/prescription with 24%. Monthly one analgesic was prescribed per prescription with 38.8%. Utilization of analgesics in term of DDD/100 Bed-days was 55.26; Drugs will be evaluated per prescription as per prescribing indicators of WHO was done, the average no. of drugs per prescription was found to be 0.45, percentage of drugs prescribed by generic name was found to be 13.3%, percentage of encounters with antibiotics prescribed were found to be 94.4%, In ratio percentage of drugs prescribed from the national list of essential medicine was found to be 92.6%. This study would help to facilitate better health care delivery.

First and second wave of COVID-19: A comparative study of tertiary care hospitalized patients in Jalgaon, Maharashtra

2021 ◽  
Vol 19 (3) ◽  
pp. 23-29
Author(s):  
Yogita G Bavaskar ◽  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical History ◽  
Care Hospital ◽  
Age Group ◽  
Number Of Patients ◽  
The Mean ◽  
Collection Form ◽  
Time Of Admission ◽  
Second Wave

Background: Most of the countries including India have witnessed two or more waves of Covid 19 pandemic. The present study was conducted to compare the differences in clinico-demographic characteristics and outcomes of Covid 19 patients admitted in first and second wave of Covid 19 pandemic in a tertiary care hospital at Jalgaon, Maharashtra. Methods: A retrospective observational study was conducted at a tertiary care Dedicated Covid hospital for Covid 19 at Jalgaon, Maharashtra. All microbiologically proven corona positive patients were included in the study. The demographic records and clinical history was extracted from the case history sheets of the patients from first as well as second wave using standardized data collection form. Clinical outcome of the patients, i.e., development of complications, death or discharge was also recorded for each enrolled subject. Results: 3845 patients of Covid-19 admitted in the hospital during the first wave of epidemic and 2956 patients during second wave of the epidemic were included in the study. The mean age of patients admitted in the second wave was significantly lower as compared to first [48.77(15.31) years vs 50.23 (14.33) years, P<0.005]. There is increase in proportion of patients in the age group of < 15 years in second wave as compared to first wave (74/2956, 2.5% vs 52/3845, 1.3%). The number of patients requiring admission in ICU at the time of admission increased by 13% in second wave as compared to first wave. [827/2956 (28%) vs 577/3845(15%), P<0.0001]. More than half of the patients who got admitted for Covid 19 in first as well as second wave were having one or more comorbidities.But the proportion of the patients with previous co-morbities was significantly higher in second wave (1684/2956, 57% vs 1960/ 3845, 51%, P= 0.0004). The mortality was also higher in second wave (533/2956, 18.03% vs 541/3845, 14%, P=0.0004). Conclusions: The demographic, clinical characteristics and outcome of Covid 19 patients was different in first and second wave of pandemic with involvement of younger patients, increased rates of admission to ICU and more mortality in the second wave as compared to first wave of the pandemic.

A CLINICOEPIDEMIOLOGICAL STUDY ON PAEDERUS DERMATITIS IN A TERTIARY CARE CENTRE, CHENNAI

2021 ◽  
pp. 25-27
Author(s):  
P. Mohan ◽  
P. Revathi Guru ◽  
V. Sudha ◽  
L. Balamurugan ◽  
Pavithra Gunasekaran ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sudden Onset ◽  
The Body ◽  
Care Hospital ◽  
Age Group ◽  
Common Condition ◽  
Tertiary Care Centre ◽  
Linear Lesions ◽  
Paederus Dermatitis

Paederus dermatitis is a form of irritant contact dermatitis due to contact with certain insects of the genus Paederus presenting with mostly erythematous linear lesions of sudden onset on exposed parts of the body. To study the clinico epi Aim: demiological features in patients with Paederus dermatitis. A retrospective analysis of clinicoepidemiological Materials & Methods: features of patients affected with Paederus dermatitis who had attended the Dermatology OPD, in a tertiary care hospital between January 2018 to December 2019 was done. All the required data had been collected from the OPD records and details were tabulated and analysed. A total of 56 patients had been affected with Result: Paederus dermatitis during the study period, of which 32 were males and 24 were females. 41out of 56 (73.21%) of patients presented between the months of August and December. Most common age group affected were between 11 to 30 yrs, with front and back of neck being the most common affected sites. In 42 out of the 56 patients the lesions resolved with post inammatory hyperpigmentation. Conclusion: Paederus dermatitis is a common condition that is often misdiagnosed and hence awareness is required for the clinicians and the general public to prevent it.

scholarly journals Adverse Drug Reaction Policy in a Tertiary Care Hospital

2015 ◽  
Vol 3 (1) ◽  
pp. 41-47
Author(s):  
V Aggarwal ◽  
Shakti Kumar Gupta ◽  
DK Sharma ◽  
S Arya ◽  
S Singh
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Healthcare Providers ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Population ◽  
Personnel Paramédical

ABSTRACT Adverse drug reactions (ADRs) are a significant cause of morbidity and mortality and contribute to the incidence of adverse events, resulting in increased healthcare costs. Healthcare providers need to understand their role and responsibility in the detection, management, documentation, and reporting of ADRs. The purpose of this study is to provide guidelines regarding the procedure of reporting ADRs to hospital authority. It was a descriptive cross-sectional study carried out between April and August 2013. The study population included doctors, nursing personnel, paramedical staff and quality managers of tertiary care hospital from one public and two private hospitals. Interaction was done with study population against the back drop of the checklist and ADR policy was formulated. How to cite this article Singh S, Gupta SK, Arya S, Sharma DK, Aggarwal V. Adverse Drug Reaction Policy in a Tertiary Care Hospital. Int J Res Foundation Hosp Healthc Adm 2015; 3(1):41-47.

scholarly journals Epidemiological study of burn injury with special reference to its prevention- A Nine-year retrospective study from a tertiary care hospital of West Bengal, India

2015 ◽  
Vol 7 (1) ◽  
pp. 70-75 ◽  
Author(s):  
Shib Shankar Kuiri ◽  
Bikash Chandra Ghosh ◽  
Nilay Mandal ◽  
Mintu Mohan Nandi ◽  
Tusar Kanti Saradar ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Injury Risk ◽  
West Bengal ◽  
Burn Injury ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Burn Injuries ◽  
Care Hospital ◽  
Burn Patients ◽  
Age Group

Aims and Objectives: We conducted a retrospective analysis among 1984 burn patients to study the incidence, prevalence of burn injury, its various types and modes (actual event behind the burn injury), risk factors and to find out the preventive measures.Materials and Methods: The retrospective study was carried out among 1984 patients having burn injuries, admitted in a tertiary care hospital of West Bengal, India over a period of nine years. The sources of information were the admission registers and the patients' folders from the medical records department. The Ethical clearance was taken from the Institutional Ethical Committee. The information obtained included age, sex, whether accidental or suicidal, etiology of burn injury and particularly the mechanism of injury. Results: Females were mostly affected (83%) in comparison to males. Among the study population, most of the burn patients were in the age group of 21-30yrs i.e. 35.3%. The number of burn patients were less in number in the age group of 11-20yrs i.e. 7.3%. Most of the burn injuries (87%) were accidental. Suicidal burns occurred in 10% cases. Of which about 1/3rd of the cases were due to dowry related issues.  A significant number of teenagers also attempted suicides due to trivial reasons (e.g. failure in examination, quarrelling with parents). Gas oven related injuries occurred in 2.7% cases. Oil lamps (‘kupi’), candles and hurricane-lanterns, diyas were also responsible to some extent in rural India for flame burns(5%). Smoking related burn injuries occurred in 1.7% cases. Scald injuries occurred in 14% cases. Chemical injuries (0.3%) were due to spillage of unlabelled bottles of acid/alkali. Electrical burn injury occurred in 4.9% cases. Conclusion: Burn injury prevention is not easy, but to avoid the significant morbidity and mortality following injury we have to prevent it by any means. A coordinated and dedicated approach among social workers , medical and paramedical personnel, administrators can only minimize the incidence of burn.Asian Journal of Medical Sciences Vol.7(1) 2015 70-75

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