Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections

Aims and Objectives: To comparatively evaluate, the effect of preoperative single dose, of paracetamol and ibuprofen on PIP, using two different rotary instruments. Materials and Methods: 60 patients were randomly premedicated, with either paracetamol or ibuprofen and canal was instrumented, with either Hyflex or Protaper Gold files. PIP was evaluated at 6, 12, 24, 48 and 72 hrs. Results: Lower incidence and intensity of PIP, occurred in patients, premedicated with Ibuprofen and where canal was instrumented with Hyflex. Conclusion: Use of Ibuprofen, as a premedication during endodontic treatment, with Hyflex rotary instruments, decreases PIP.

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3 Single-Dose Oritavancin Treatment of Acute Bacterial Skin and Skin Structure Infections in Intravenous Drug Users: Results from SOLO Trials

Annals of Emergency Medicine ◽

10.1016/j.annemergmed.2015.07.032 ◽

2015 ◽

Vol 66 (4) ◽

pp. S2

Author(s):

C.V. Pollack ◽

S. Good ◽

M. Wikler

Keyword(s):

Single Dose ◽

Drug Users ◽

Intravenous Drug ◽

Intravenous Drug Users ◽

Skin Structure

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Single-dose dalbavancin and patient satisfaction in an outpatient setting in the treatment of acute bacterial skin and skin structure infections

Journal of Global Antimicrobial Resistance ◽

10.1016/j.jgar.2019.02.007 ◽

2019 ◽

Vol 17 ◽

pp. 60-65 ◽

Cited By ~ 7

Author(s):

Urania Rappo ◽

Pedro L. Gonzalez ◽

Sailaja Puttagunta ◽

Karthik Akinapelli ◽

Katelyn Keyloun ◽

...

Keyword(s):

Patient Satisfaction ◽

Single Dose ◽

Outpatient Setting ◽

Skin Structure

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A comparative evaluation of the safety and immunogenicity of a single dose of unbuffered oral rhesus rotavirus serotype 3, rhesus/human reassortant serotypes 1, 2 and 4 and combined (tetravalent) vaccines in healthy infants

Vaccine ◽

10.1016/0264-410x(93)90260-5 ◽

1993 ◽

Vol 11 (7) ◽

pp. 747-753 ◽

Cited By ~ 2

Author(s):

Michael E. Pichichero ◽

Steven M. Marsocci ◽

Anne B. Francis ◽

John L. Green ◽

Frank A. Disney ◽

...

Keyword(s):

Single Dose ◽

Comparative Evaluation ◽

Healthy Infants

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Single-Dose Dalbavancin: A Review in Acute Bacterial Skin and Skin Structure Infections

Drugs ◽

10.1007/s40265-016-0666-0 ◽

2016 ◽

Vol 77 (1) ◽

pp. 75-83 ◽

Cited By ~ 13

Author(s):

Karly P. Garnock-Jones

Keyword(s):

Single Dose ◽

Skin Structure

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Comparative evaluation of various analgesics in irreversible pulpitis to reduce pain

Bioinformation ◽

10.6026//97320630017313 ◽

2021 ◽

Vol 17 (2) ◽

pp. 313-319

Author(s):

Pradeep Solete ◽

Keyword(s):

Clinical Trial ◽

Single Dose ◽

Comparative Evaluation ◽

Severe Pain ◽

Statistical Significance ◽

Control Group ◽

Time Intervals ◽

Root Canals ◽

Pain Scores ◽

Irreversible Pulpitis

It is of interest to evaluate a single dose of three different analgesics compared to placebo in patients with symptomatic irreversible pulpitis. 120 patients were enrolled with severe pain in this prospective clinical trial. Patients were randomly divided into four groups after shaping and cleaning of root canals. This includes placebo, piroxicam 20mg, acetaminophen 325mg with aceclofenac sodium 100mg and acetaminophen 650mg. Participants were given a questionnaire to note the pain scores at various time intervals (6 hrs, 12 hrs, and 24 hrs) along with the respective tablets in a concealed manner. Data thus collected was analyzed for statistical significance. The severity of pain decreased in all the three interventional groups compared to the control group (p <0.01) at 6 hours. Zerodol-P and dolonex showed better pain reduction in comparison to the placebo and dolo 650 group (p <0.05) at 12 and 24 hours. Data shows that both zerodol-P and dolonex groups had similar effects at all time intervals. Thus, a single dose of analgesic such as Zerodol-P and Dolonex following shaping and cleaning of root canals relieved pain at all time intervals of the treatment. However, Dolo 650 performed better during the initial 6hrs after completion of the shaping and cleaning of root canals compared to the placebo.

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