A comparative study on efficacy of different treatment modalities of oral submucous fibrosis evaluated by clinical staging in population of Southern Rajasthan

ABSTRACT Oral submucous fibrosis (OSMF) is a premalignant condition associated with restricted mouth opening. Oral submucous fibrosis is poorly understood and unsatisfactorily treated disease. Serious complication is the risk of development of oral carcinoma. Different treatment modalities like medical, surgical, physical therapy or combination are used to improve the condition of the patient. Surgical treatment is usually indicated in late and irreversible stage of the disease. Successful use of nasolabial flap in the management of OSMF is presented. How to cite this article Jamdade V, Sharma S, Chitlangia P, Amit. Nasolabial Flap in the Management of Oral Submucous Fibrosis. J Mahatma Gandhi Univ Med Sci Tech 2016;1(1):27-29.

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Comparative study of the efficacy of lycopene and aloe vera in the treatment of oral submucous fibrosis

International Journal of Health & Allied Sciences ◽

10.4103/2278-344x.149216 ◽

2015 ◽

Vol 4 (1) ◽

pp. 13 ◽

Cited By ~ 9

Author(s):

Santosh Patil ◽

Rohit Sahu ◽

MG Sghaireen ◽

SomnathReddy Kunsi ◽

Sneha Maheshwari

Keyword(s):

Comparative Study ◽

Oral Submucous Fibrosis ◽

Aloe Vera ◽

Submucous Fibrosis

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Does Clinical Staging and Histological Grading Show Parallelism In Oral Submucous Fibrosis? A Retrospective Study from an Indian City

Journal of Interdisciplinary Histopathology ◽

10.5455/jihp.20140406010651 ◽

2014 ◽

Vol 2 (3) ◽

pp. 145 ◽

Cited By ~ 1

Author(s):

Manish Narayan ◽

Dominic Augustine ◽

Tina Jacob ◽

Kumar Shrivastava ◽

Deepti Shrivastava ◽

...

Keyword(s):

Retrospective Study ◽

Oral Submucous Fibrosis ◽

Clinical Staging ◽

Histological Grading ◽

Indian City ◽

Submucous Fibrosis

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Excision of Oral Submucous Fibrosis and Reconstruction with Full Thickness Skin Graft: A Case Study and Review of the Literature

Case Reports in Dentistry ◽

10.1155/2012/628301 ◽

2012 ◽

Vol 2012 ◽

pp. 1-5

Author(s):

Ahmad Alshadwi ◽

Ishwar Bhatia

Keyword(s):

Skin Graft ◽

Buccal Mucosa ◽

Oral Submucous Fibrosis ◽

Treatment Modalities ◽

Full Thickness ◽

Review Of The Literature ◽

Full Thickness Skin Graft ◽

Full Thickness Skin ◽

Thickness Skin ◽

Submucous Fibrosis

Oral submucous fibrosis is a chronic debilitating disease characterized by gradually increasing fibrosis of the oral cavity and pharynx, mainly the buccal mucosa, resulting in trismus. The highest incidence of oral submucous fibrosis is seen in South India due to various deleterious habits. In spite of the numerous medical modalities employed in the management of oral submucous fibrosis, occasionally surgical intervention becomes inevitable. Various surgical approaches have been used to reconstruct the surgical defects following excision of fibrous bands. Full thickness skin grafts have been described in the literature with variable outcomes. In the present study a 38-year-old male presented with severe oral submucous fibrosis of the buccal mucosa, which was successfully treated and reconstructed using full thickness skin graft with stable functional result after one year of treatment. An integrated review of the literature regarding etiology, histopathology, diagnostic, and treatment modalities of the disease follows.

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A comparative study to evaluate the efficacy of lycopene and curcumin in oral submucous fibrosis patients: A randomized clinical trial

Indian Journal of Dental Research ◽

10.4103/ijdr.ijdr_551_16 ◽

2018 ◽

Vol 29 (3) ◽

pp. 303 ◽

Cited By ~ 12

Author(s):

Gargi Saran ◽

Deepak Umapathy ◽

Neeta Misra ◽

ShivakumarGaniga Channaiah ◽

Priya Singh ◽

...

Keyword(s):

Clinical Trial ◽

Comparative Study ◽

Randomized Clinical Trial ◽

Oral Submucous Fibrosis ◽

Submucous Fibrosis

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EFFICACY OF ANTIOXIDANT WITH ALOE VERA GEL VERSUS INTRA-LESIONAL STEROIDS IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS - A PROSPECTIVE COMPARATIVE STUDY

Pakistan Armed Forces Medical Journal ◽

10.51253/pafmj.v71isuppl-3.7921 ◽

2021 ◽

Vol 71 (Suppl-3) ◽

pp. S526-29

Author(s):

Muhammad Tahir ◽

Asim Abbas ◽

Faiz Ul Hassan Nawaz ◽

Mohsin Raza ◽

Atif Rafique ◽

...

Keyword(s):

Comparative Study ◽

Lipoic Acid ◽

Oral Submucous Fibrosis ◽

Aloe Vera ◽

Mouth Opening ◽

Burning Sensation ◽

Alpha Lipoic Acid ◽

Aloe Vera Gel ◽

Prospective Comparative Study ◽

Submucous Fibrosis

Objective: To compared efficacy of alpha lipoic acid (antioxidant medication) and aloe vera gel together versus intralesional steroids (hydrocortisone) in management of oral submucous fibrosis by evaluating post treatment clinical features of mouth opening and burning sensation. Study Design: A prospective comparative study. Place and Duration of Study: Department of ENT, Combined Military Hospital, Malir Karachi, from Jul 2018 to Mar 2020. Methodology: Twenty-eight patients were involved in the research and were distributed into two groups, I and II. Alpha lipoid acid with aloe vera gel was given in group I and hydrocortisone was given in group II. Burning sensation and mouth opening were recorded both at start and at monthly interval later on for three consecutive months. The data collected were statistically analyzed by using SPSS-22. Results: A significant lessening in burning sensation (p<0.001) and improvement in mouth opening were noticed in both groups. However, comparison between alpha lipoic acid with aloe vera gel group versus hydrocortisone group showed almost similar results. Conclusion: Alpha lipoic acid and aloe vera gel can significantly improve oral submucous fibrosis clinically. So, these can be utilized as an alternative option in cases where intralesional steroid is poorly tolerated or is contraindicated.

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Emancipators in oral sub mucous fibrosis: An update

International Journal of Dentistry Research ◽

10.31254/dentistry.2021.6207 ◽

2021 ◽

Vol 6 (2) ◽

pp. 59-64

Author(s):

Subharina Mahapatra ◽

◽

Manjula Hebbale ◽

Amit Mhapuskar ◽

Richa Jain ◽

...

Keyword(s):

Surgical Treatment ◽

Literature Search ◽

Oral Submucous Fibrosis ◽

Mouth Opening ◽

Treatment Modalities ◽

Established Method ◽

Pharmacological Agents ◽

Cochrane Database ◽

Submucous Fibrosis ◽

Oral Sub Mucous Fibrosis

Oral submucous fibrosis is a chronic insidious oral mucosal condition causing trismus and reduced mouth opening and it is affecting predominantly Indian and other Asians. The treatment of trismus requires combination of pharmacological agents, surgical therapy and physiotherapy, the latter is essential for preventing relapse due to postoperative inactivity and scarring as well as for improvement of mouth opening. Computerized literature search was performed from 1993 till 2021 to select eligible articles from the following databases: PUBMED [MEDLINE], SCOPUS, SCIENCE DIRECT, and COCHRANE DATABASE using specific keywords. The search was limited to articles published as full text in English, which were screened by two reviewers for eligibility.This article describes in depth about various appliances, devices used in oral submucous fibrosis. The devices can be used along with pharmacological and surgical treatment modalities or can be used alone. Mouth exercise is also well-established method to improve mouth opening and also to prevent postsurgical relapse. This article is one of the rare article that describes all the appliances together either directly used or indirectly used for the case of microstomia due to oral sub mucous fibrosis.

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