scholarly journals Is there any benefit of integrating computer-assisted learning with conventional teaching format in pharmacology to demonstrate the effects of different drugs on mean arterial blood pressure in an anesthetized dog?: A comparative study

2017 ◽  
Vol 8 (2) ◽  
pp. 181 ◽  
Author(s):  
Parama Sengupta ◽  
Abhishek Sharma ◽  
Nina Das
Keyword(s):  
Blood Pressure ◽  
Comparative Study ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Computer Assisted ◽  
Computer Assisted Learning ◽  
Arterial Blood ◽  
Teaching Format ◽  
Conventional Teaching

Fluid percussion brain injury in the developing and adult rat: a comparative study of mortality, morphology, intracranial pressure and mean arterial blood pressure

1996 ◽  
Vol 95 (2) ◽  
pp. 272-282 ◽  
Author(s):  
Mayumi L. Prins ◽  
Stefan M. Lee ◽  
Charles L.Y. Cheng ◽  
Donald P. Becker ◽  
David A. Hovda
Keyword(s):  
Blood Pressure ◽  
Brain Injury ◽  
Intracranial Pressure ◽  
Comparative Study ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Adult Rat ◽  
Fluid Percussion ◽  
Arterial Blood

scholarly journals A Comparative study of IV Labetalol and IV Hydralazine on mean arterial blood pressure changes in pregnant women with hypertensive emergency

2016 ◽  
Vol 4 (6) ◽  
pp. 2256-2259
Author(s):  
Trivedi Swati ◽  
Vyas Lila ◽  
Ratnu Lata ◽  
Gupta Prachi ◽  
Agarwal Pratibha ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Comparative Study ◽  
Pregnant Women ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Hypertensive Emergency ◽  
Arterial Blood ◽  
Pressure Changes

Cardiovascular Effects of Micromeria graeca (L.) Benth. ex Rchb in Normotensive and Hypertensive Rats

2020 ◽  
Vol 20 (8) ◽  
pp. 1253-1261
Author(s):  
Mourad Akdad ◽  
Mohamed Eddouks
Keyword(s):  
Blood Pressure ◽  
Cardiovascular System ◽  
Arterial Blood Pressure ◽  
Antihypertensive Activity ◽  
Computer Assisted ◽  
Hypertensive Rats ◽  
Vasorelaxant Effect ◽  
Arterial Blood

Aims: The present study was performed in order to analyze the antihypertensive activity of Micromeria graeca (L.) Benth. ex Rchb. Background: Micromeria graeca (L.) Benth. ex Rchb is an aromatic and medicinal plant belonging to the Lamiaceae family. This herb is used to treat various pathologies such as cardiovascular disorders. Meanwhile, its pharmacological effects on the cardiovascular system have not been studied. Objective: The present study aimed to evaluate the effect of aqueous extract of aerial parts of Micromeria graeca (AEMG) on the cardiovascular system in normotensive and hypertensive rats. Methods: In this study, the cardiovascular effect of AEMG was evaluated using in vivo and in vitro investigations. In order to assess the acute effect of AEMG on the cardiovascular system, anesthetized L-NAME-hypertensive and normotensive rats received AEMG (100 mg/kg) orally and arterial blood pressure parameters were monitored during six hours. In the sub-chronic study, rats were orally treated for one week, followed by blood pressure assessment during one week of treatment. Blood pressure was measured using a tail-cuff and a computer-assisted monitoring device. In the second experiment, isolated rat aortic ring pre-contracted with Epinephrine (EP) or KCl was used to assess the vasorelaxant effect of AEMG. Results: Oral administration of AEMG (100 mg/kg) provoked a decrease of arterial blood pressure parameters in hypertensive rats. In addition, AEMG induced a vasorelaxant effect in thoracic aortic rings pre-contracted with EP (10 μM) or KCl (80 mM). This effect was attenuated in the presence of propranolol and methylene blue. While in the presence of glibenclamide, L-NAME, nifedipine or Indomethacin, the vasorelaxant effect was not affected. Conclusion: This study showed that Micromeria graeca possesses a potent antihypertensive effect and relaxes the vascular smooth muscle through β-adrenergic and cGMP pathways.

scholarly journals ANTENATAL STEROIDS DO NOT AFFECT MEAN ARTERIAL BLOOD PRESSURE OR NEED FOR TREATMENT OF HYPOTENSION IN INFANTS ≤1250 GRAMS DURING THE FIRST DAY OF LIFE. † 1462

1996 ◽  
Vol 39 ◽  
pp. 246-246
Author(s):  
Juan P Solano ◽  
Cory Fergus ◽  
Roderic H Phibbs ◽  
Joseph A Kitterman ◽  
Augusto Sola
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Need For Treatment ◽  
Arterial Blood ◽  
Antenatal Steroids

Liberal vs. conservative vasopressor use to maintain mean arterial blood pressure during resuscitation of septic shock: an observational study

2007 ◽  
Vol 34 (1) ◽  
pp. 157-162 ◽  
Author(s):  
Sanjay Subramanian ◽  
Murat Yilmaz ◽  
Ahmer Rehman ◽  
Rolf D. Hubmayr ◽  
Bekele Afessa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Septic Shock ◽  
Observational Study ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Arterial Blood ◽  
Vasopressor Use

scholarly journals Distributions of Local Oxygen Saturation and Its Response to Changes of Mean Arterial Blood Pressure in the Cerebral Cortex Adjacent to Arteriovenous Malformations

Stroke ◽  
1999 ◽  
Vol 30 (12) ◽  
pp. 2623-2630 ◽  
Author(s):  
Bernhard Meyer ◽  
Carlo Schaller ◽  
Christian Frenkel ◽  
Bernd Ebeling ◽  
Johannes Schramm
Keyword(s):  
Blood Pressure ◽  
Cerebral Cortex ◽  
Oxygen Saturation ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Arteriovenous Malformations ◽  
Arterial Blood ◽  
Local Oxygen

Cerebral hemorrhage and edema following brain biopsy in rats: significance of mean arterial blood pressure

2000 ◽  
Vol 92 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Helene Benveniste ◽  
Katie R. Kim ◽  
Laurence W. Hedlund ◽  
John W. Kim ◽  
Allan H. Friedman
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Neurosurgical Procedures ◽  
Shr Rats ◽  
Mr Microscopy ◽  
Content Type ◽  
Wky Rats ◽  
Arterial Blood ◽  
Fine Print

Object. It is taken for granted that patients with hypertension are at greater risk for intracerebral hemorrhage during neurosurgical procedures than patients with normal blood pressure. The anesthesiologist, therefore, maintains mean arterial blood pressure (MABP) near the lower end of the autoregulation curve, which in patients with preexisting hypertension can be as high as 110 to 130 mm Hg. Whether patients with long-standing hypertension experience more hemorrhage than normotensive patients after brain surgery if their blood pressure is maintained at the presurgical hypertensive level is currently unknown. The authors tested this hypothesis experimentally in a rodent model.Methods. Hemorrhage and edema in the brain after needle biopsy was measured in vivo by using three-dimensional magnetic resonance (MR) microscopy in the following groups: WKY rats, acutely hypertensive WKY rats, spontaneously hypertensive rats (SHR strain), and SHR rats treated with either sodium nitroprusside or nicardipine. Group differences were compared using Tukey's studentized range test followed by individual pairwise comparisons of groups and adjusted for multiple comparisons.There were no differences in PaCO2, pH, and body temperature among the groups. The findings in this study indicated that only acutely hypertensive WKY rats had larger volumes of hemorrhage. Chronically hypertensive SHR rats with MABPs of 130 mm Hg did not have larger hemorrhages than normotensive rats. There were no differences in edema volumes among groups.Conclusions. The brains of SHR rats with elevated systemic MABPs are probably protected against excessive hemorrhage during surgery because of greater resistance in the larger cerebral arteries and, thus, reduced cerebral intravascular pressures.

Cerebroelectrical Depression Following Surfactant Treatment in Preterm Neonates

PEDIATRICS ◽  
1992 ◽  
Vol 89 (4) ◽  
pp. 643-647 ◽  
Author(s):  
Lena Hellström-Westas ◽  
Nils W. Svenningsen ◽  
Angela H. Bell ◽  
Liselotte Skov ◽  
Gorm Greisen
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Intraventricular Hemorrhage ◽  
Preterm Neonates ◽  
Cerebral Function ◽  
Surfactant Treatment ◽  
Arterial Blood ◽  
Cerebral Dysfunction ◽  
Almost All

During surfactant treatment of respiratory distress syndrome, 23 premature newborns were investigated with continuous amplitude-integrated electroencephalography (cerebral function monitors). Simultaneously, arterial blood pressure and transcutaneous blood gas values were recorded. A short(<10 minutes) but significant decrease in cerebral activity was seen in almost all neonates immediately after the surfactant instillation, in spite of an improved pulmonary function. In 21 of 23 neonates, a transient fall in mean arterial blood pressure of 9.3 mm Hg (mean) occurred coincidently with the cerebral reaction. Neonates in whom intraventricular hemorrhage developed tended to have lower presurfactant mean arterial blood pressure (P> .05), but they had a significantly lower mean arterial blood pressure after surfactant instillation (P < .05). No other differences were found between neonates in whom intraventricular hemorrhage developed and those without intraventricular hemorrhage. The present findings demonstrate that an acute cerebral dysfunction may occur after surfactant instillation. In some vulnerable neonates with arterial hypotension and severe pulmonary immaturity,the fall in mean arterial blood pressure may increase the risk of cerebral complications and could be related to an unchanged rate of intraventricular hemorrhage after surfactant treatment.

scholarly journals Modeling Cerebral Blood Flow Dependence on Carbon Dioxide and Mean Arterial Blood Pressure in the Immature Brain With Accounting for the Germinal Matrix

2018 ◽  
Vol 9 ◽  
Author(s):  
Irina Sidorenko ◽  
Varvara Turova ◽  
Nikolai Botkin ◽  
Laura Eckardt ◽  
Ana Alves-Pinto ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Immature Brain ◽  
Germinal Matrix ◽  
Arterial Blood ◽  
Flow Dependence
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