Splanchnic hemodynamics as a predictor of feeding tolerance in preterm neonates

2018 ◽  
Vol 7 (4) ◽  
pp. 243
Author(s):  
MarwaHosni Abdel Hamed ◽  
HodaLotfy El Sayed ◽  
DinaGarir Abdel Hady

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 83 ◽  
Author(s):  
Silvia Martini ◽  
Arianna Aceti ◽  
Silvia Galletti ◽  
Isadora Beghetti ◽  
Giacomo Faldella ◽  
...  

The management of enteral feeds in preterm infants with a hemodynamically significant patent ductus arteriosus (hs-PDA) is a major challenge for neonatologists due to the fear of gastrointestinal (GI) complications. This review aims to analyze the available evidence on the complex relation between the presence and management of PDA, enteral feeding practices, and GI outcomes in the preterm population. There is limited evidence, based on small and heterogeneous trials, that hs-PDA may affect the splanchnic hemodynamic response to enteral feeds. While the presence of PDA seems a risk factor for adverse GI outcomes, the benefits of feeding withholding during pharmacological PDA treatment are controversial. The lack of robust evidence in support of or against a timely feeding introduction or feeding withholding during pharmacological PDA closure in preterm neonates does not allow to draw any related recommendation. While waiting for further data, the feeding management of this population should be carefully evaluated and possibly individualized on the basis of the infants’ hemodynamic and clinical characteristics. Large, multicentric trials would help to better clarify the physiological mechanisms underlying the development of gut hypoperfusion, and to evaluate the impact of enteral feeds on splanchnic hemodynamics in relation to PDA features and treatment.



QJM ◽  
2018 ◽  
Vol 111 (suppl_1) ◽  
Author(s):  
H L El Sayed ◽  
M F Nassar ◽  
M H A bdel-Hamed ◽  
D G Abdel Hady


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Minoo Fallahi ◽  
Mohammad Kazemian ◽  
Saeed Hojat Kashani ◽  
Saleheh Tajalli ◽  
Naeeme Taslimi

Background: Recently, the correlation between necrotizing enterocolitis (NEC) and packed cell transfusion (PCT) has been identified. Evidence shows that 25 - 35% of NEC cases are associated with PCT. Objectives: this study aimed to determine the association between PCT and feeding tolerance in healthy preterm newborns. Methods: Materials and Methods: This clinical trial was performed on preterm infants, admitted to the neonatal intensive care unit (NICU) of Mofid Children's Hospital, Tehran, Iran, from April 2017 to May 2018. A total of 70 healthy premature infants (birth weight < 1500 g and gestational age < 32 weeks) with enteral feeding, who required PCT, were included in this study. The eligible infants were divided into two groups by simple randomization. In the intervention group (n = 35), breastfeeding was withheld only during PCT and then continued as usual. On the other hand, in the control group (n = 35), feeding was performed as usual, regardless of PCT. Feeding tolerance within the first 72 hours post-transfusion was compared between the two groups. Sick newborns were excluded from the study. Data analysis was performed in SPSS version 20. Results: The mean gestational age, birth weight, and postnatal age of the neonates were 30.13 weeks, 1245.71 g, and 17 days in the intervention group and 29.97 weeks, 1169.43 g, and 15.46 days in the control group, respectively; there was no significant difference between the two groups. Except for pre-transfusion hemoglobin and hematocrit levels, other characteristics of the two groups were similar. Feeding tolerance was reported in 32 (91.2%), 33 (94.73%), and 34 (97.1%) newborns at 24, 48, and 72 hours post-transfusion in both groups, without any significant difference. There was no significant difference between neonates with and without feeding tolerance in either of the groups. Conclusions: According to the present results, withholding feeding during PCT is not necessary in healthy preterm neonates with a good general condition, and continued breastfeeding seems to be a safe option.



2018 ◽  
Vol 11 (2) ◽  
pp. 117-131 ◽  
Author(s):  
Nathália de Figueiredo Silva ◽  
Maria Beatriz Martins Linhares ◽  
Cláudia Maria Gaspardo


2012 ◽  
Vol 224 (07) ◽  
Author(s):  
L Gortner ◽  
P Ahnert ◽  
W Göpel ◽  
P Nürnberg


2015 ◽  
Vol 46 (S 01) ◽  
Author(s):  
M. Cremer ◽  
K. Jost ◽  
S. Schulzke ◽  
P. Weber ◽  
A. Datta


2017 ◽  
Vol 04 (01) ◽  
pp. 27-30
Author(s):  
Rahul Sinha ◽  
K Venkatnarayan ◽  
Shamsher Dalal ◽  
B M John ◽  
V Sabid Syed


2012 ◽  
Vol 3 (2) ◽  
pp. 218-220
Author(s):  
PANKTI D DESAI ◽  
◽  
HETAL D VORA ◽  
S H MANSURI S H MANSURI


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