Clinical Profile of Patients with Hepatic Encephalopathy in Cirrhosis of Liver

2019 ◽  
Vol 14 (3) ◽  
pp. 130 ◽  
Author(s):  
AmanPratap Singh ◽  
Shilpa Bawankule ◽  
Sunil Kumar ◽  
Abhay Gaidhane ◽  
Mahalaque Quazi
Keyword(s):  
Hepatic Encephalopathy ◽  
Clinical Profile ◽  
Cirrhosis Of Liver

Serum Zinc Levels in Cirrhotic Patients Attending General and Specialty Hospitals, Yangon

2019 ◽  
Vol 31 (3) ◽  
pp. 251-256
Keyword(s):  
Clinical Practice ◽  
Hepatic Encephalopathy ◽  
Zinc Deficiency ◽  
Serum Zinc ◽  
Zinc Level ◽  
The Body ◽  
Serum Zinc Level ◽  
Cross Sectional ◽  
Cirrhotic Patients ◽  
Cirrhosis Of Liver

Cirrhosis of liver is one of the common medical problem in daily clinical practice and one of the leading causes of morbidity and mortality. Zinc is an essential trace elements for human and plays in many biological roles in the body. Among them, zinc deficiency is thought to be involved in metabolism of ammonia and causes hyperammonia that worsen hepatic encephalopathy. This study aimed to find out the severity of cirrhosis of liver was by Child Turcotte Pugh score and to investigate the associations between serum zinc level and severity of cirrhosis. A hospital-based cross-sectional descriptive study was performed on 78 patients with different underlying causes of cirrhosis of liver at the Medical Units of Yangon General Hospital and Yangon Specialty Hospital. Among the study population, Child grade A was found to be 28.21%, Child grade B was 30.77% and Child grade C was 41.03%. Regarding result of serum zinc level, 62.8% were low level, 28.2% were within normal level and 8.9% were high level. Mean value of serum zinc level in grade A was 0.68 mg/l, grade B was 0.54 mg/l and grade C was 0.48 mg/l (p=0.00). It was found out that there was a high prevalence of zinc deficiency in severe cirrhotic patients. The zinc level was significantly lowest among patients with Child-Pugh C as compare to those with Child-Pugh B and C. Severity of zinc deficiency should be requested for supplementation therapy in cirrhotic patients as to prevent complications such as hepatic encephalopathy, hepatocellular carcinoma and liver failure. Screening for zinc deficiency may need in these patients with more advanced cirrhosis because it seems to be a marker of advanced liver disease and it can be deducted that awareness of serum zinc level among cirrhotic patients is very important in clinical practice.

Study of Clinical Profile and Outcome of Metabolic Encephalopathy in Patients Admitted at HSK Hospital, Bagalkot, Karnataka

2021 ◽  
Vol 8 (33) ◽  
pp. 3134-3138
Keyword(s):  
General Medicine ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Clinical State ◽  
Common Symptom ◽  
Cross Sectional ◽  
Altered Level ◽  
Metabolic Encephalopathy ◽  
Altered Sensorium ◽  
Cirrhosis Of Liver

BACKGROUND Metabolic encephalopathy (ME) is one of the most frequently encountered and broadly defined diagnoses by the physicians in the intensive care setting. ME is a clinical state characterized by cerebral dysfunction in the absence of structural brain disease. The causes are many and often multifactorial. The purpose of study was to evaluate various causes, clinical profile, and outcome in patients with ME. METHODS This is a hospital based, observational, cross sectional study, conducted in ICU of Department of General medicine, S.N. Medical College, Bagalkot. Patients with head trauma, organic causes of altered sensorium, psychiatric conditions were excluded. RESULTS Mean age was 51.22 ± 17.24 years. Majority were males. Diabetes was the most common comorbidity found followed by cirrhosis of liver and hypertension. Septic causes were found to be the most common aetiology. 80.7 % recovered from the disease and death was noted in 19.3 % patients. CONCLUSIONS All the patients with ME had altered level of consciousness with fever being the most common symptom. Most of them were males, most common aetiology was septic cause, and recovery was seen in about 80.7 % of patients. KEYWORDS Metabolic Encephalopathy, Altered Sensorium, Sepsis

Secondary prophylaxis of hepatic encephalopathy in cirrhosis of liver

2018 ◽  
Vol 30 (8) ◽  
pp. 951-958 ◽  
Author(s):  
Shivakumar Varakanahalli ◽  
Barjesh C. Sharma ◽  
Siddharth Srivastava ◽  
Sanjeev Sachdeva ◽  
Amol S. Dahale
Keyword(s):  
Hepatic Encephalopathy ◽  
Secondary Prophylaxis ◽  
Cirrhosis Of Liver

scholarly journals Prevalence of and Factors Associated With Minimal Hepatic Encephalopathy in Patients With Cirrhosis of Liver

2018 ◽  
Vol 8 (2) ◽  
pp. 156-161 ◽  
Author(s):  
Abhijith Bale ◽  
C. Ganesh Pai ◽  
Shiran Shetty ◽  
Girisha Balaraju ◽  
Anurag Shetty
Keyword(s):  
Hepatic Encephalopathy ◽  
Minimal Hepatic Encephalopathy ◽  
Factors Associated ◽  
Cirrhosis Of Liver

Prediction of Hepatic Encephalopathy by Liver Stiffness Measurement with Fibroscan in Patients with Cirrhosis of Liver

2016 ◽  
Vol 6 ◽  
pp. S56
Author(s):  
Ahmed Lutful Moben ◽  
Mohammad Noor-E-Alam ◽  
M.A. Rahim ◽  
Faiz Ahmad Khondoker ◽  
Farjana Majid ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Cirrhosis Of Liver

scholarly journals A STUDY OF USEFULNESS OF PSYCHOMETRIC TESTS IN DIAGNOSIS OF MINIMAL HEPATIC ENCEPHALOPATHY IN PATIENTS WITH CIRRHOSIS OF LIVER

2016 ◽  
Vol 5 (79) ◽  
pp. 5889-5893
Author(s):  
Sundaramurthy Ganesan ◽  
Ashok Kumar Subramaniam ◽  
Natarajan Kandasamy ◽  
Vijayanand Radhakrishnan
Keyword(s):  
Hepatic Encephalopathy ◽  
Minimal Hepatic Encephalopathy ◽  
Psychometric Tests ◽  
Cirrhosis Of Liver

scholarly journals Clinical Profile of Alcoholic Liver Disease in Saveetha Medical College and Hospital and Its Association with Type, Amount and duration of Alcohol Consumption

2021 ◽  
pp. 132-138
Author(s):  
S. Aswathi ◽  
V. Vikrannth
Keyword(s):  
Liver Disease ◽  
Hepatic Encephalopathy ◽  
Alcohol Consumption ◽  
Alcoholic Liver Disease ◽  
Alcohol Intake ◽  
Prognostic Markers ◽  
Meld Score ◽  
Clinical Profile ◽  
Dependent Relation ◽  
Dose Dependent

Introduction: Alcoholic liver disease is a caused as a result of overconsuming alcohol that damages the liver, leading to inflammation, and scarring. It is often fatal with mortality and morbidity worldwide. Many studies in various countries show contradictory results about the role of amount, type and duration of alcohol exposure in determining the risk to develop ALD. This study aims to evaluate clinical profile of ALD in south Indian population and to correlation of disease severity with alcohol intake. Material and Methods: A total of 50 patients of ALD were evaluated to correlate their clinical findings, biochemical parameters, prognostic markers (Discriminant function [DF] score, Model for end-stage liver disease [MELD] score and Child-Pugh score) and with their alcohol intake data in form of type, amount and duration of alcohol intake. Results: Hepatic encephalopathy, neutrophil to lymphocyte ratio (NLR) and all three prognostic scores showed a dose-dependent relation with the amount of alcohol intake (p <0.05). The results showed that the duration of alcohol had a positive impact on the results. NLR correlates well with all prognostic markers (p <0.05 for NLR's Spearman correlation with DF score and Child-Pugh Score), more so with MELD score (p <0.0001); and complications like hepatic encephalopathy and hepato-renal syndrome. Conclusion: In this study we conclude that there is significant dose dependent relation of ALD along with its complications, prognostic markers and NLR with the amount, type and duration of alcohol consumption. Although the type of alcohol consumption didn’t have much influence on the results, amount of intake had a correlation with NLR.

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