scholarly journals Effect of scaling and root planing on levels of 8-hydroxydeoxyguanosine in gingival crevicular fluid of chronic periodontitis patients with and without Type II diabetes mellitus

2017 ◽  
Vol 21 (3) ◽  
pp. 201 ◽  
Author(s):  
MariaSubash Aaron Muthuraj ◽  
Srihari Janakiram ◽  
Koshy Chithresan ◽  
ArunParappa Maradi ◽  
PraveenKrishna Maddur ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Periodontitis ◽  
Type Ii Diabetes ◽  
Gingival Crevicular Fluid ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Crevicular Fluid

scholarly journals A COMPARATIVE EVALUATION OF C-REACTIVE PROTEIN GCF LEVEL IN PERIODONTITIS PATIENTS AFTER SCALING AND ROOT PLANING WITH AND WITHOUT DIODE LASER

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Sangeeta Roy ◽  
C.S. Joshi ◽  
Pradeep Shukla ◽  
Gaurav Malhotra ◽  
Prerna Kataria ◽  
...  
Keyword(s):  
Diode Laser ◽  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Type I ◽  
Scaling And Root Planing ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Root Planing ◽  
Crevicular Fluid

Background and Objectives: C?reactive protein (CRP) is a type I acute phase reactant. A number of studies have reported elevated gingival crevicular fluid (GCF) CRP levels in periodontitis subjects, which decrease following periodontal therapy. Effect of diode laser as an adjuct to Scaling & Root planing is also well stablished. The aim of the present study was to evaluate the effect of periodontal treatment SRP with diode laser, on CRP levels in GCF in patients with chronic periodontitis. Materials and Methods: A total of 40 subjects with moderate periodontitis based on community periodontal index scores, were included in the study. Periodontal therapy was performed dividing each side of jaw as a group (Split mouth); one side SRP alone & another Diode laser with SRP. GCF was collected from each subject at Baseline (prior to treatment) and 1 month after periodontal therapy. The collected sample was subjected to biochemical analysis to detect CRP levels by using a commercially available highly sensitive kit. Results: The present study demonstrated that the mean CRP values at baseline were found to be 0.11043mg/l in side-I (side treated with SRP alone); 0.11042mg/l in side-II (side treated with SRP & laser) of the patient, which reduced to 0.4148 mg/L in side I and 0.3985mg/L in side II after treatment, which are highly significant according to statistical analysis but the changes between two sides were non- significant statistically. Interpretation and Conclusion: Within the limitations of this study, it can be concluded that periodontal therapy is able to reduce the GCF C reactive protein level significantly, but there was no statistically significant result in CRP level, between sides treated with SRP & SRP with laser. Key words: Chronic periodontitis, C?reactive protein, gingival crevicular fluid, Scaling and root planing, Diode laser

scholarly journals SALIVARY PARAMETERS IN DIABETICS TYPE II WITH SEVERE CHRONIC PERIODONTITIS

2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Júlia Dias Magalhães ◽  
Camila Barreto dos Santos Tolomei ◽  
Roberta Santos Tunes ◽  
Urbino da Rocha Tunes ◽  
Márcia Tosta Xavier
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Periodontitis ◽  
Type Ii Diabetes ◽  
Dental Health ◽  
Salivary Flow ◽  
Type Ii Diabetes Mellitus ◽  
Buffering Capacity ◽  
Type Ii ◽  
Commercial Kits ◽  
Systemic Condition

Periodontitis and diabetes mellitus combine systemic condition and dental health and can cause  salivary alterations. This work examined the saliva of 16 individuals with type II diabetes mellitus (DM) and severe chronic periodontitis (SCP) (G1), 11 with DM and without SCP (G2), 14 without DM with SCP (G3) and 15 without DM and without SCP (G4). The periodontal condition was evaluated, salivary flow and buffering capacity were analyzed and salivary components were measured using commercial kits. Diabetics with SCP showed a tendency to decrease the flow. The buffering capacity remains unchanged. Urea (p < 0.018) and total protein (p < 0.001) were larger and less Calcium was observed (p < 0.0001) in diabetics. In patients with SCP, the DM favored even greater urea increase. The phosphate increased in groups G1, G2 and G3 (p < 0.0001) compared to G4. The metabolism from diabetics with SCP increases salivary proteins, increasing urea resulting from amino acids degradation by periodontal bacterias.

Efficacy of subgingivally delivered atorvastatin and simvastatin as an adjunct to scaling and root planing

2015 ◽  
Vol 30 (4) ◽  
Author(s):  
Sai M. Surve ◽  
Anirudh B. Acharya ◽  
Srinath L. Thakur
Keyword(s):  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Local Delivery ◽  
Control Group ◽  
Clinical Parameters ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Significant Difference ◽  
Group 2 ◽  
Crevicular Fluid

AbstractThe current understanding of the pathogenesis of periodontal disease has resulted in adjunctive use of various pharmacologic agents in periodontal therapy. The objective of this investigation was to assess the efficacy of atorvastatin and simvastatin (because of their pleiotropic properties) as an adjunct to dental scaling and root planing (SRP) by local delivery, i.e. placing them subgingivally, in the treatment of chronic periodontitis.Local delivery systems for atorvastatin and simvastatin were prepared in sodium alginate suspension to be administered with calcium chloride solution. Patients diagnosed with chronic periodontitis were grouped as group 1, receiving SRP only (control), group 2, receiving SRP with subgingival delivery of 1.2% simvastatin, and group 3, receiving SRP with subgingival delivery of 1.2% atorvastatin. Clinical parameters and interleukin (IL) 1α levels in the gingival crevicular fluid (GCF) were assessed.All three groups showed significant reductions in clinical parameters and IL-1α levels in the GCF (p<0.05). However, the test groups did not show any statistically significant difference when compared with control.Subgingivally delivered atorvastatin and simvastatin as an adjunct to SRP is efficacious but did not demonstrate any added benefit as compared with SRP alone.

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