scholarly journals To Compare Diagnostic Ability of Contrast-Enhanced Three-Dimensional T1-SPACE with Three-Dimensional Fluid-Attenuated Inversion Recovery and Three-Dimensional T1-Magnetization Prepared Rapid Gradient Echo Magnetic Resonance Sequences in Patients of Meningitis

2019 ◽  
Vol 10 (01) ◽  
pp. 48-53 ◽  
Author(s):  
Sudesh Kumar ◽  
Suresh Kumar ◽  
Mukesh Surya ◽  
Anjali Mahajan ◽  
Sanjiv Sharma
Keyword(s):  
Magnetic Resonance ◽  
Three Dimensional ◽  
Sylvian Fissure ◽  
Inversion Recovery ◽  
Gradient Echo ◽  
Meningeal Enhancement ◽  
Leptomeningeal Enhancement ◽  
Fluid Attenuated Inversion Recovery ◽  
3D Flair ◽  
Basal Cisterns

ABSTRACT Aims: The aim of this study is to compare postcontrast three-dimensional (3D) T1-Sampling perfection with application-optimized contrasts by using different flip angle evolutions, 3D fluid-attenuated inversion recovery (FLAIR), and 3D T1-magnetization prepared rapid gradient echo (MPRAGE) sequences in patients of meningitis. Settings and Design: A hospital-based cross-sectional study done in the Department of Radiodiagnosis, IGMC Shimla for a period of 1 year from June 1, 2016, to May 30, 2017. Subjects and Methods: A total of 30 patients suspected of meningitis underwent magnetic resonance imaging evaluation with postcontrast 3D T1-MPRAGE, 3D T1-SPACE, and 3D FLAIR sequences. The abnormal leptomeningeal enhancement was noted by two radiologists together on these sequences and scores were given to the abnormal leptomeningeal enhancement. Statistical Analysis Used: The sensitivity of 3D T1-SPACE, 3D T1-MPRAGE, and 3D FLAIR was calculated and compared. The level of agreement between these sequences was assessed by kappa coefficient. P < 0.05 was taken as statistically significant. Results: 3D T1-SPACE shows superiority in meningeal enhancement along basal cisterns, Sylvian fissure and along cerebral convexities. It is also found to be better in delineating parenchymal lesions. 3D FLAIR failed to demonstrate enhancement along cerebral convexities however found to be better than 3D T1-MPRAGE in delineating enhancement along basal cisterns and Sylvian fissures. 3D T1-MPRAGE has shown subtle enhancement in basal cisterns, Sylvian fissure and along cerebral convexities. 3D T1-SPACE, 3D FLAIR, and 3D T1-MPRAGE has sensitivity of 91.67%, 66.67%, and 54.17%, respectively. Conclusion: Postcontrast 3D T1-SPACE sequence is an excellent tool than postcontrast 3D T1-MPRAGE and 3D FLAIR sequences in the evaluation of meningeal enhancement and depiction of additional lesions in brain parenchyma.

Cortical involvement and leptomeningeal inflammation in myelin oligodendrocyte glycoprotein antibody disease: A three-dimensional fluid-attenuated inversion recovery MRI study

2021 ◽  
pp. 135245852110343
Author(s):  
Dimitrios Tzanetakos ◽  
John S Tzartos ◽  
Aigli G Vakrakou ◽  
Marianthi Breza ◽  
Georgios Velonakis ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Median Number ◽  
Myelin Oligodendrocyte Glycoprotein ◽  
Inversion Recovery ◽  
Cortical Lesion ◽  
Mri Findings ◽  
Meningeal Inflammation ◽  
Fluid Attenuated Inversion Recovery ◽  
3D Flair

Background: Cortical demyelination and meningeal inflammation have been detected neuropathologically in multiple sclerosis (MS) and recently in myelin oligodendrocyte glycoprotein antibody disease (MOGAD). Objectives: To assess in vivo cortical and leptomeningeal involvement in MOGAD. Methods: We prospectively evaluated 11 MOGAD and 12 relapsing-remitting MS (RRMS) patients combining three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) and 3D-T1-weighted (3D-T1w) sequences at 3-Tesla magnetic resonance imaging (MRI). Leptomeningeal contrast enhancement (LMCE) was assessed on 3D-FLAIR post-gadolinium (3D-FLAIRGd). Cerebral cortical lesions (CCLs) were classified as either intracortical–subpial (IC–SP) or leukocortical (LC). Results: CCLs were present in 8/11 MOGAD and 12/12 RRMS patients, with the number of CCLs being significantly lower in MOGAD (median (interquartile range (IQR)) 3 (0.5–4) vs 12 (4.75–19), p = 0.0032). In MOGAD, IC–SP lesions were slightly more prevalent than LC lesions (2 (0–2.5) vs 1 (0–2), p = 0.6579); whereas in RRMS, IC–SP lesions were less prevalent than LC lesions (3.5 (2.75–5.5) vs 9 (2–12.75), p = 0.27). LMCE was observed in 3/11 MOGAD and 1/12 RRMS patients; MOGAD with LMCE showed an increased median number of CCLs compared with MOGAD without LMCE (8 (4–9) vs 2.5 (0.75–3.25), p = 0.34). No correlation was observed between MOGAD MRI findings and (a) MOGAD duration, (b) serum MOG-immunoglobulin G1 titers, and (c) oligoclonal band presence. Conclusion: We described cortical lesion topography and detected for the first time LMCE using 3D-FLAIRGd sequences in MOGAD patients.

Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in a patient with relapsing polychondritis

2014 ◽  
Vol 128 (2) ◽  
pp. 192-194 ◽  
Author(s):  
M Kato ◽  
N Katayama ◽  
S Naganawa ◽  
T Nakashima
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Standard Dose ◽  
Three Dimensional ◽  
Relapsing Polychondritis ◽  
Inversion Recovery ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Radiological Report ◽  
Fluid Attenuated Inversion Recovery

AbstractObjective:We report three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in a patient with relapsing polychondritis.Method:Case report.Result:A 76-year-old woman initially presented with bilateral auricular swelling together with dyspnoea. Three months later, she experienced left hearing loss and recurrent vertigo. A biopsy of the auricle was performed and relapsing polychondritis was diagnosed. The patient underwent three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging 4 hours after intravenous injection of a standard dose of gadolinium. Gadolinium enhancement was visible throughout the vestibule and the endolymphatic space could not be visualised, suggesting breakdown of the blood–labyrinth barrier.Conclusion:This is the first radiological report to demonstrate breakdown of the blood–labyrinth barrier in a case of relapsing polychondritis with inner ear impairment.

Three - dimensional fluid attenuated inversion recovery sequence on 3 tesla magnetic resonace imaging in cranial nerve pathologies: Two case reports

2021 ◽  
Author(s):  
Thuyet Dinh Van
Keyword(s):  
Cranial Nerve ◽  
Case Reports ◽  
Three Dimensional ◽  
Inversion Recovery ◽  
Inversion Recovery Sequence ◽  
Recovery Sequence ◽  
Flair Sequence ◽  
Fluid Attenuated Inversion Recovery ◽  
Fluid Pulsation ◽  
3D Flair

Three - dimensional fluid attenuated inversion recovery sequence (3D-FLAIR) was introduced as a practical sequence which helps to reduce the cerebrospinal fluid pulsation and flow artefacts of conventional 2D acquisition and brings contiguous slices, ability in reformatting in variable planes which are typical features of 3D acquisition. 3D - FLAIR has been applied on assessing several neurologic pathologies. In this article, we introduce the application of 3D - FLAIR sequence without contrast enhancement on detecting abnormalities of cranial nerve pathology by presenting two cases, acute vestibular neuritis and facial nerve palsy. We suggest that 3D - FLAIR is the relatively useful sequence in detecting cranial nerve pathologies.

Usefulness of three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging to detect inner-ear abnormalities in patients with sudden sensorineural hearing loss

2014 ◽  
Vol 129 (1) ◽  
pp. 11-15 ◽  
Author(s):  
T Tanigawa ◽  
R Shibata ◽  
H Tanaka ◽  
M Gosho ◽  
N Katahira ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Hearing Loss ◽  
Magnetic Resonance ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Three Dimensional ◽  
Inversion Recovery ◽  
Sensorineural Hearing ◽  
Resonance Imaging ◽  
Fluid Attenuated Inversion Recovery

AbstractObjective:Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging has been used to detect alterations in the composition of inner-ear fluid. This study investigated the association between hearing level and the signal intensity of pre- and post-contrast three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging in patients with sudden-onset sensorineural hearing loss.Method:Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging was performed in 18 patients with sudden-onset sensorineural hearing loss: 12 patients with mild-to-moderate sensorineural hearing loss (baseline hearing levels of 60 dB or less) and 6 patients with severe-to-profound sensorineural hearing loss (baseline hearing levels of more than 60 dB).Results:High-intensity signals in the inner ear were observed in two of the six patients (33 per cent) with severe-to-profound sensorineural hearing loss, but not in those with mild-to-moderate sensorineural hearing loss (mid-p test, p = 0.049). These signals were observed on magnetic resonance imaging scans 6 or 18 days after sensorineural hearing loss onset.Conclusion:The results indicate that three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging is not a useful tool for detecting inner-ear abnormalities in patients with mild sensorineural hearing loss.

Susac’s syndrome: Leptomeningeal enhancement on 3D FLAIR MRI

2016 ◽  
Vol 22 (7) ◽  
pp. 972-974 ◽  
Author(s):  
Renate Engisch ◽  
David S Titelbaum ◽  
Lara Chilver-Stainer ◽  
Frauke Kellner-Weldon
Keyword(s):  
Symptom Severity ◽  
Three Dimensional ◽  
Clinical Activity ◽  
Resonance Imaging ◽  
Leptomeningeal Enhancement ◽  
Susac’S Syndrome ◽  
Size Number ◽  
Contrast Enhanced ◽  
Fluid Attenuated Inversion Recovery ◽  
3D Flair

Background: Contrast-enhanced (ce) fluid-attenuated inversion recovery magnetic resonance imaging (FLAIR MRI) has recently been shown to identify leptomeningeal pathology in multiple sclerosis. Objective: To demonstrate leptomeningeal enhancement on three-dimensional (3D) FLAIR in a case of Susac’s syndrome. Methods: Leptomeningeal enhancement was correlated with clinical activity over 20 months and compared to retinal fluorescein angiography. Results: The size, number, and location of leptomeningeal enhancement varied over time and generally correlated with symptom severity. The appearance was remarkably similar to that of retinal vasculopathy. Conclusion: Ce 3D FLAIR may aid in diagnosis and understanding of pathophysiology in Susac’s syndrome and may serve as a biomarker for disease activity.

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