A clinico epidemiological analysis of dengue deaths in children during outbreaks in the year 2013 and 2017: A retrospective observational study from a tertiary care teaching hospital in South India

Background: Rational prescribing is an essential skill for every prescriber. However many times it seems a difficult task for various reasons. Such practices ultimately increase the mortality, morbidity and financial burden on the patient. Hence, we aimed our study to evaluate appropriateness of prescription pattern according to WHO drug prescribing indicators, few complementary indicators and classify prescription errors.Methods: A retrospective observational study, conducted in medical record section of tertiary care teaching hospital of Maharashtra during the period of 6 months. Total 400 randomly selected prescriptions from Medicine inpatient wards were scrutinized.Results: Average number of drugs per prescription was 5.20 trending towards polypharmacy. Drugs prescribed by generic name were 13.88%, injectable drugs were part of 93.50% prescriptions, 78.25% prescriptions contained an antimicrobial agent and Percentage of drugs prescribed from NELM 2011 was 72.36%. Illegible handwriting in 68% cases was the important cause of prescription errors. These errors found in 73% of prescriptions.Conclusions: The present study showed that the practices were trending towards irrational prescribing. Polypharmacy and illegible prescriptions were dominated. Regular prescription audit will help to rectify such practices. Also, there is an urgent need of sensitization of prescriber through new treatment guidelines, seminar, presentations and discussions on regular basis.

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A 6 months retrospective observational study to assess the rationality and effectiveness of snake bite management in a tertiary care teaching hospital of rural Bengal, India

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20183946 ◽

2018 ◽

Vol 7 (10) ◽

pp. 2047

Author(s):

Satrajit Dan ◽

Ananya Mandal ◽

Abhijit Das ◽

Sourav Chakrabarty ◽

Tanmoy Gangopadhyay

Keyword(s):

Observational Study ◽

Teaching Hospital ◽

West Bengal ◽

Tertiary Care ◽

Snake Bite ◽

Retrospective Observational Study ◽

Standard Protocol ◽

Venomous Snake ◽

Tertiary Care Teaching Hospital ◽

Care Teaching

Background: Snake envenomation is a common life-threatening problem encountered all-over West Bengal particularly in the rural areas. There are a large number of patients attending the Emergency unit and being admitted to the Medicine ward, some in the intensive care unit (ICU) and intensive therapy unit (ITU) of the tertiary health care facilities. The objective of this study was to assess rationality and effectiveness of management of venomous snake bite following standard protocol – Standard treatment guidelines of Government of West Bengal and National snakebite management protocol of Government of India.Methods: This was a retrospective observational study of six months (May - October 2017) duration. Data were collected from the treatment records of patients admitted with history of snake bite in the Medicine ward, ICU and ITU of tertiary care teaching hospital of rural Bengal.Results: Of the 63 venomous bite patients, most (82.5 %) were diagnosed to have features of neurotoxic envenomation. All of them (100%) received anti-snake venom (ASV). There was no incidence of anaphylactic reaction as well as any serious adverse drug reaction following ASV administration. Two patients developed acute renal failure, needed haemodialysis. Overall percentage of mortality was 3.2%.Conclusions: The survival rate in venomous snake bite is found to be high in this institution. The practice of snake bite management is found to be adherent with standard protocol. A multicentric study of longer duration is suggested to draw a firm conclusion.

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