Assessment of local wound healing complications after groin surgery: a comparative study between two wound closure techniques

Abstract Objective: Wound suturing is a procedure performed at many medical specialties. This study aims to analyze the effectiveness of wound closure techniques by recognizing the common suturing techniques and materials used in different types of wounds among surgeons and emergency physicians in Mecca hospitals and assessing their awareness about the factors contributing to scars formation and improper wound healing.Result: Choosing the simple interrupted technique exceeded 50% among all other types of studied wounds. The other most common techniques among participants were the subcuticular and vertical mattress, respectively, also using stapler was limited to some wound types. This study showed a high level of awareness among participants with significant p-values (P<0.05) of Strongly agree and Agree regarding the essential factors affecting wound healing and scars formation. The result gives an insight into the most common suture techniques and materials used in wound closure. There are wide variations in selecting these techniques and materials among the participants. Also, it showed that there is good awareness among participants about factors that lead to scar formation.

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The clinical impact of hydroresponsive dressings in dynamic wound healing: Part I

Journal of Wound Care ◽

10.12968/jowc.2021.30.1.15 ◽

2021 ◽

Vol 30 (1) ◽

pp. 15-24

Author(s):

Francois Sterpione ◽

Karine Mas ◽

Mark Rippon ◽

Alan Rogers ◽

Georges Mayeux ◽

...

Keyword(s):

Wound Healing ◽

Comparative Study ◽

Wound Dressing ◽

Wound Closure ◽

Clinical Effectiveness ◽

Clinical Impact ◽

Wound Dressings ◽

Primary Measurement ◽

Clinical Healing ◽

Wound Bed Preparation

Objective: Management of any wound, either acute or hard-to-heal, might involve the use of multiple and different wound dressings in its treatment. This approach is necessary to overcome the myriad of clinical challenges the wound presents, as well as any underlying comorbidities that might affect the clinical outcomes. This article describes the clinical effectiveness of a coordinated wound dressing treatment regimen. Method: This was an open-labelled non-comparative study involving patients with a variety of hard-to-heal and acute wounds of differing levels of severity, but all of which required removal of devitalised tissue to enable wound healing to progress. The first phase used the hydroresponsive wound dressing HydroClean (PAUL HARTMANN AG, Germany). The PUSH score was used as the primary measurement parameter. Results: A total of 86 patients (38 male/48 female), with a mean age of 67.7±21.7 years, took part in the study. The results showed that the hydroresponsive dressing was effective in managing wound exudate production and promoting wound cleansing and debridement, supporting good wound bed preparation. Wound closure was observed in 16/86 (18.6%) wounds at the end of the study (20 weeks). This enabled clinicians to switch to alternative wound dressings to promote subsequent clinical healing outcomes. Conclusion: In this study, the hydroresponsive wound dressing was highly effective in preparing a clean wound bed such that the next stage of wound healing could be supported.

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Comparison of the ficus for the wound healing activity in various species

International Journal of Research in Phytochemistry and Pharmacology ◽

10.26452/ijrpp.v10i4.1381 ◽

2020 ◽

Vol 10 (4) ◽

pp. 67-70

Author(s):

Mothilal K ◽

Akila CR ◽

Mahender K ◽

Chaitanya Kumar K ◽

Ravi D

Keyword(s):

Wound Healing ◽

Wound Closure ◽

Subcutaneous Tissue ◽

Significant Activity ◽

Herbal Extracts ◽

Standard Drug ◽

Excision Wound ◽

Injuries And Wounds ◽

Skin Conditions ◽

Wound Healing Activity

Injuries and wounds are any sorts of damage to the skin or subcutaneous tissue. Usually, any wounds of such sorts are self-healed. Sometimes, there may be a delay in healing, and that delay is caused due to the functional delays in various processes of wound healing. All the Ficus plants show similar activities like the antioxidant, anti-inflammatory and wound healing properties 7including skin conditions like ulcers and rheumatism. The anthelmintic property and immunomodulatory are also seen. The herbal extracts of the same family of Ficus in different plants were investigated for the wound healing activity in the excision wound method, and the extracts showed significant activity compared to the drug. All the extracts showed a better healing ability, but the extract of FBO-100 showed the highest activity followed by FMO followed by FHO and finally the FRO. Overall, the activity of the extract ointment was comparable and was significant compared to the standard drug ointment. The wound closure of the extract ointment treated groups were better and were completed in 12 days, and the activity was more than 96%. The herbal extracts of the same family of Ficus in different plants were investigated for the wound healing activity in the excision wound method, and the extracts showed significant activity compared to the drug. The plants of microcarpa, benghalensis, religiosa and hispida are compared for the activity, and the order showed for the activity was FBO>FMO>FHO>FRO.

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Wound Closure (Allgower) Versus Secondary Open Wound Healing After Removal of the External Fixator

Case Medical Research ◽

10.31525/ct1-nct03842956 ◽

2000 ◽

Author(s):

Keyword(s):

Wound Healing ◽

External Fixator ◽

Wound Closure ◽

Open Wound

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Overexpression of the Oral Mucosa-Specific microRNA-31 Promotes Skin Wound Closure

International Journal of Molecular Sciences ◽

10.3390/ijms20153679 ◽

2019 ◽

Vol 20 (15) ◽

pp. 3679 ◽

Cited By ~ 3

Author(s):

Lin Chen ◽

Alyne Simões ◽

Zujian Chen ◽

Yan Zhao ◽

Xinming Wu ◽

...

Keyword(s):

Wound Healing ◽

Oral Mucosa ◽

Wound Closure ◽

Expression Patterns ◽

Skin Wound ◽

Skin Wound Healing ◽

Specific Expression ◽

Keratinocyte Proliferation

Wounds within the oral mucosa are known to heal more rapidly than skin wounds. Recent studies suggest that differences in the microRNAome profiles may underlie the exceptional healing that occurs in oral mucosa. Here, we test whether skin wound-healing can be accelerating by increasing the levels of oral mucosa-specific microRNAs. A panel of 57 differentially expressed high expresser microRNAs were identified based on our previously published miR-seq dataset of paired skin and oral mucosal wound-healing [Sci. Rep. (2019) 9:7160]. These microRNAs were further grouped into 5 clusters based on their expression patterns, and their differential expression was confirmed by TaqMan-based quantification of LCM-captured epithelial cells from the wound edges. Of these 5 clusters, Cluster IV (consisting of 8 microRNAs, including miR-31) is most intriguing due to its tissue-specific expression pattern and temporal changes during wound-healing. The in vitro functional assays show that ectopic transfection of miR-31 consistently enhanced keratinocyte proliferation and migration. In vivo, miR-31 mimic treatment led to a statistically significant acceleration of wound closure. Our results demonstrate that wound-healing can be enhanced in skin through the overexpression of microRNAs that are highly expressed in the privileged healing response of the oral mucosa.

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Surgical Strategies to Promote Cutaneous Healing

Medical Sciences ◽

10.3390/medsci9020045 ◽

2021 ◽

Vol 9 (2) ◽

pp. 45

Author(s):

Ines Maria Niederstätter ◽

Jennifer Lynn Schiefer ◽

Paul Christian Fuchs

Keyword(s):

Wound Healing ◽

Wound Closure ◽

Chronic Wounds ◽

Treatment Algorithm ◽

Surgical Site Infections ◽

Repair Process ◽

Suture Technique ◽

The Body ◽

Wound Debridement ◽

Reconstructive Ladder

Usually, cutaneous wound healing does not get impeded and processes uneventfully, reaching wound closure easily. The goal of this repair process is to restore the integrity of the body surface by creating a resilient and stable scar. Surgical practice and strategies have an impact on the course of wound healing and the later appearance of the scar. By considering elementary surgical principles, such as the appropriate suture material, suture technique, and timing, optimal conditions for wound healing can be created. Wounds can be differentiated into clean wounds, clean–contaminated wounds, contaminated, and infected/dirty wounds, based on the degree of colonization or infection. Furthermore, a distinction is made between acute and chronic wounds. The latter are wounds that persist for longer than 4–6 weeks. Care should be taken to avoid surgical site infections in the management of wounds by maintaining sterile working conditions, using antimicrobial working techniques, and implementing the principles of preoperative antibiotics. Successful wound closure is influenced by wound debridement. Wound debridement removes necrotic tissue, senescent and non-migratory cells, bacteria, and foreign bodies that impede wound healing. Additionally, the reconstructive ladder is a viable and partially overlapping treatment algorithm in plastic surgery to achieve successful wound closure.

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Fabrication of gelatin/sodium alginate-poly (3-hydroxybutyric acid) bilayer electrospun biosheet as wound healing material in nursing care on pediatric fracture surgery

Journal of Industrial Textiles ◽

10.1177/1528083720976346 ◽

2020 ◽

pp. 152808372097634

Author(s):

Daiqi Jiang ◽

Zaiju Tong ◽

Lingjun Peng ◽

Lingzhi Zhang ◽

Qianzi Ruan ◽

...

Keyword(s):

Wound Healing ◽

Sodium Alginate ◽

Wound Closure ◽

Skin Wound ◽

Tissue Formation ◽

Hydroxybutyric Acid ◽

Physiochemical Properties ◽

Pediatric Fracture ◽

Fracture Surgery

Novel the bilayered electrospun biosheet with rapid cell mimiciking and proliferative efficacy will be suitable for wound healing application. The optimized concentration of gelatin (G) and sodium alginate (A) biosheet with nanofibrous Poly (3-hydroxybutyric acid) (P) as a bilayered elctrospun matrix through electrospinning. The engineered GAP bilayered biosheet involves tissue formation at extra cellular matrix (ECM) which further characterized its function in vitro and invivo. Here we fabricated GAP which exhibit better physiochemical properties, biological and mechanical properties with superior prosomes it enhance air passable at skin wounds. The Bilayered biosheet matrix possess better biocompatibility, cell adherence, fructuous and cell to cell interactions evaluated using cell lines. Furthermore, GAP bilayered matrix regulates growth factors to attain maximum wound closure efficiency during invivo. Thus, the fabricated GAP electrospun biosheet would be a possible wound dressing for skin wound applications.

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934 Remote one-to-one virtual surgical skills training: Evolving the delivery of operative skills training in the UK

British Journal of Surgery ◽

10.1093/bjs/znab134.178 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

Christian Asher ◽

Ibrahim Ibrahim ◽

Eyfrossini Katsarma

Keyword(s):

Surgical Training ◽

Wound Closure ◽

Cost Effective ◽

Skills Training ◽

Training Programme ◽

Surgical Skills ◽

Wound Closure Techniques ◽

Surgical Skills Training ◽

Speciality Training ◽

One To One

Abstract Introduction COVID-19 has had an unprecedented effect on surgical training, including prerequisite entry-level courses to speciality training. We describe the implementation of a virtual, one-to-one training programme aimed at the acquisition and retention of operative skills. Methods Enrolment commenced 8th May 2020 for wound closure techniques or an extended programme including tendon repairs, delivered by Specialist Registrars in Plastic Surgery using Zoom® (v. 5.0.5) via mobile device. Participant feedback was collected retrospectively using a 5-point scale following course completion. Results 5 participants completed the wound closure programme, and 3 the extended programme, over an average of 5 weeks, with 2 sessions per week. 5 participants were male, 3 female and were of the following grades: 2 CT2, 4 FY2, 1 FY1 and 1 medical student. A total of 103.5 hours of training was recorded to 7 September 2020. Participants reported that all virtual skills taught were readily transferable to the theatre environment. Following the course, all participants felt confident to complete the skills learnt independently, rating the course as excellent. Conclusions The COVID-19 crisis has placed insurmountable obstacles in the face of surgical training. With further validation, we aim to develop surgical skills training with virtual, easily reproducible, cost-effective, trainee centred programmes.

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