scholarly journals Carotid blowout syndrome: An oncological emergency less discussed

2017 ◽  
Vol 06 (02) ◽  
pp. 085-086
Author(s):  
Karthik K. Prasad ◽  
Nagesh T. Sirsath ◽  
Kiran V. Naiknaware ◽  
K. Sandhya Rani ◽  
Manish S Bhatia
Author(s):  
Jitender Singh ◽  
Tarika Sharma ◽  
Taraprasad Tripathy

Abstract Background Carotid blowout syndrome (CBS) refers to a fatal hemorrhagic complication of cervical carotid arteries that occurs due to rupture of the extracranial carotid artery or one of its major branches in patients treated for head and neck malignancy. In this article, we will discuss two different spectrum of CBS and endovascular approach. Case presentation Two cases of per oral bleeding presented in the emergency department. After patients were hemodynamically stabilized, CT angiography was done which showed type II CBS and type III CBS, respectively. This was followed by transfemoral supra-aortic digital subtraction angiogram coil embolization with scaffolding and anchoring technique, respectively, for the patients. Conclusions Early recognition of the predictors of CBS by a multidisciplinary team is critical. The endovascular treatment approach is relatively safe and effective with low rates of morbidity and mortality compared to surgical approach in CBS.


2019 ◽  
Vol 49 (9) ◽  
pp. 839-844
Author(s):  
Fumihiko Matsumoto ◽  
Satoko Matsumura ◽  
Taisuke Mori ◽  
Ayaka Mori ◽  
Go Omura ◽  
...  

CCA ligation at the proximal side of the bleeding point under local anesthesia and before rupture is a treatment option for patients at high risk of CBS.


2013 ◽  
Vol 58 (5) ◽  
pp. 1226-1235 ◽  
Author(s):  
Hsueh-Ju Lu ◽  
Kuo-Wei Chen ◽  
Ming-Huang Chen ◽  
Pen-Yuan Chu ◽  
Shyh-Kuan Tai ◽  
...  

2018 ◽  
Vol Volume 10 ◽  
pp. 5617-5628 ◽  
Author(s):  
Carlos Suárez ◽  
Verónica Fernández-Alvarez ◽  
Marc Hamoir ◽  
William M. Mendenhall ◽  
Primož Strojan ◽  
...  

Head & Neck ◽  
2014 ◽  
Vol 37 (6) ◽  
pp. 794-799 ◽  
Author(s):  
Kun-Chih Chen ◽  
Ting-Ting Yen ◽  
Yi-Ling Hsieh ◽  
Hung-Chieh Chen ◽  
Rong-San Jiang ◽  
...  

Author(s):  
John C. Chaloupka ◽  
Walter S. Lesley ◽  
Minako Hayakawa ◽  
Shih-Wei Hsu

2020 ◽  
Vol 13 (3) ◽  
pp. 1116-1124
Author(s):  
Wiebke Wesemüller ◽  
Christian Taverna

Tumor lysis syndrome (TLS) is a hemato-oncological emergency characterized by metabolic and electrolyte imbalances which are associated with disintegrating tumor cells. The syndrome is frequently observed when starting cytotoxic treatment of hematological malignancies, while the incidence of spontaneous tumor lysis prior to the start of tumor therapy is rare. Here, we present a case of spontaneous TLS in a male patient who was referred with unspecific symptoms and suspected metastatic malignancy. He developed acute renal failure before the diagnosis of a high-grade B-cell lymphoma (double hit lymphoma) and start of therapy. Although the course of TLS would have required intensive care, the patient rejected such treatment for personal reasons and died soon after the discontinuation of therapy. The case emphasizes the life-saving relevance of early detection and appropriate treatment of TLS. It also demonstrates the importance of actively screening for TLS, primarily in patients with malignant diseases and high tumor load, even if they are not receiving cytotoxic therapy.


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S939-S940
Author(s):  
Arish Noor ◽  
Aakash Desai ◽  
Varun Tandon ◽  
Pradeep K Siddappa ◽  
Kathir Balakumaran ◽  
...  

Abstract Background Febrile neutropenia (FBN) is a life-threatening oncological emergency requiring hospitalization and early treatment with broad-spectrum antibiotics. We aimed to study differences in infection-related outcomes for febrile neutropenia in various malignancies. Methods The National Inpatient Sample (NIS) data set was queried from 2007 to 2014 to identify all patients with a diagnosis of neutropenic fever (ICD-9: 780.6x and 288.5x or 288.0x or 284.1x). Diagnoses for various cancers were determined via their respective Clinical Classification Software (CCS) codes. Diagnoses of pneumonia (481.x, 482x), bacterial meningitis (320.x), Clostridium difficile (008.45), infectious colitis due to neoplastic agents (009.x), urinary tract infection (599.0x), pyelonephritis (590.1x, 590.80), skin and soft-tissue infection (682.x, 684.x, 686.8x, 686.9x), mucositis (528.01), influenza (CCS 487), sepsis (995.91), severe sepsis (995.92), septic shock (785.52), E. coli septicemia (038.42), Pseudomonas septicemia (038.43), MRSA septicemia (038.12) and Streptococcal septicemia (038.0) were identified using their respective ICD/CCS codes. Variables were analyzed via multivariate analysis using the program SAS. Results We studied 381,043 patients with FBN. Leukemia was the most common malignancy associated with FBN (140,190, patients, 36.8%). Meningitis was found to be significantly associated with brain cancer, while other infections were associated with a range of malignancies. (Table.1) Methicillin-resistant Staphylococcus aureus was associated with cancers of the bone, breast, uterus and non- hodgkins lymphoma, while other microorganisms varied across different malignancies (Table 2). Septic Shock was associated with cancer of the pancreas, lung, bone, breast, leukemia, bladder, kidney, thyroid, myeloma, prostate, testis, cervix, brain, melanoma, non-hodgkins lymphoma, compared with other malignancies (Table 3). Conclusion Pathogen-specific and targeted antibiotic therapy is the cornerstone of treatment in FBN. Our study provides evidence of specific presentations and organisms causing infections in various malignancies. We hope that further outcomes-based research will provide objective evidence of certain high-risk infections, improving patient outcomes and minimizing redundant testing. Disclosures All authors: No reported disclosures.


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