scholarly journals A Propensity Score-Matching Analysis of Transthoracic Echocardiography and Abdominal Ultrasonography for the Detection of Abdominal Aortic Aneurysms

2015 ◽  
Vol 9 ◽  
pp. CMC.S23166 ◽  
Author(s):  
Takao Kato ◽  
Seiko Ishida ◽  
Shoichi Miyamoto ◽  
Tamae Iura ◽  
Yoko Ban ◽  
...  
Keyword(s):  
Propensity Score ◽  
Propensity Score Matching ◽  
Transthoracic Echocardiography ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Comparable Efficacy ◽  
Abdominal Ultrasonography ◽  
Cross Sectional ◽  
Propensity Score Matching Analysis ◽  
Abdominal Aortic

Introduction We previously reported that the prevalence of abdominal aortic aneurysms (AAAs) was higher in patients undergoing scheduled transthoracic echocardiography (TTE) than in patients undergoing abdominal ultrasonography (AUS); however, intergroup patient backgrounds differed significantly in that report. Purpose We tested the hypothesis that TTE could detect AAA as effectively as AUS. Design A propensity score-matching analysis of a cross-sectional study was adopted as the design for this study. Methods We enrolled 7,619 and 15,433 patients scheduled to undergo TTE with additional evaluation of abdominal aorta at the end of the routine study and AUS, respectively, from 2009 to 2010 in our hospital, as reported. A propensity score for profiles of patients who underwent TTE or AUS was developed to adjust for potential confounding bias. Consequently, 4,388 patients in each group were matched for analyses. Results In propensity-matched patients, AAA was detected in 59 patients of the TTE group and in 48 patients of the AUS group; the prevalence of AAA detection did not differ significantly between TTE and AUS groups ( P = 0.331). Positive associations were observed between AAA detection and male sex (adjusted odds ratio [OR]: 3.25; 95% confidence interval [CI], 2.05-5.15; P < 0.001), older age (adjusted OR: 1.029; 95% CI: 1.01-1.04; P < 0.001), and the presence of ischemic heart disease (adjusted OR: 1.78; 95% CI: 1.04-3.03; P = 0.033) and hypertension (adjusted OR: 2.16; 95% CI: 1.38-3.37; P = 001). Conclusion TTE detected AAA with comparable efficacy as AUS in propensity-matched groups who underwent scheduled TTE and AUS.

Screening Program of Abdominal Aortic Aneurysm

Angiology ◽  
2019 ◽  
Vol 70 (5) ◽  
pp. 407-413 ◽  
Author(s):  
Muriel Sprynger ◽  
Michel Willems ◽  
Hendrik Van Damme ◽  
Benny Drieghe ◽  
J. C. Wautrecht ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Screening Program ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Ultrasound Screening ◽  
Care Providers ◽  
Abdominal Ultrasonography ◽  
Screening Programs ◽  
Abdominal Aortic ◽  
Elective Repair

In Europe, the prevalence of abdominal aortic aneurysms (AAAs) in the elderly population (≥65 year old) has declined in the past decades to <4%. Aneurysmal degeneration of the aorta is a serious and potentially life-threatening vascular disease. Abdominal aortic aneurysms typically develop subclinically and often only become symptomatic when complicated by impending rupture. Most AAAs are discovered incidentally while investigating for an unrelated pathology. Ruptured AAA is the tenth leading cause of death in Belgium (0.32% of all deaths in 2014). Health-care providers have emphasized the importance of early detection of AAA and elective repair when the rupture risk outweighs operative risk (usual diameter threshold of 55 mm). Routine AAA screening programs, consisting of a single abdominal ultrasonography at the age of 65 years, aim to reduce the number of AAA-related deaths. Does population-based ultrasound screening for AAA achieve its objective and is it cost-effective? This literature review tries to answer these challenging questions.

scholarly journals Association between Single Nucleotide Polymorphisms in Cardiovascular Developmental Critical Genes and Hypertension: A Propensity Score Matching Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Zhiqiang Zhao ◽  
Chunmei Gong ◽  
Yanfang Gao ◽  
Xiaoli Liu ◽  
Sai Wu ◽  
...  
Keyword(s):  
Propensity Score ◽  
Propensity Score Matching ◽  
Additive Model ◽  
Recessive Model ◽  
Cardiovascular Development ◽  
Dominant Model ◽  
Nucleotide Polymorphisms ◽  
Cross Sectional ◽  
Single Nucleotide ◽  
Propensity Score Matching Analysis

Cardiovascular development critical genes are key determinants in cardiovascular diseases. We hypothesize that SNPs in these genes may play critical roles in the development of hypertension. Therefore, we enrolled 516 paired hypertension patients and controls in a total of 2,742 subjects in a cross-sectional population study by the propensity score matching (PSM) method. Twenty-one SNPs from 5 cardiovascular developmental related genes were detected by the improved multiplex ligase detection reaction (iMLDR) method. Conditioned logistic regression under three different genetic models, namely, additive model, dominant model, and recessive model, was performed. The odds ratio (ORs) and 95% confidence intervals (95% CIs) were used to estimate the associations of SNPs with hypertension. We found that the distribution of genotypes at rs833061, rs3025010, and rs699947 within the VEGFA gene and the distribution of alleles at rs3025010 in hypertension subjects were different from those in controls. Both rs833061 and rs3025010 were associated with hypertension in crude models, but only rs3025010 remains associated with hypertension after adjusting with confounding factors in the additive model and the dominant model. We also found that hypertension subjects with C/T and C/C genotypes at rs3025010 had lower SBP and DBP levels. In addition, rs3025010 could interact with rs6784267 within the CCM3 gene in the association. In conclusion, our findings suggest that rs3025010 may play a role in the pathogenesis of hypertension, which may be a potential target for individualized prevention and treatment of hypertension.

Early and long-term results of open repair of inflammatory abdominal aortic aneurysms: Comparison with a propensity score-matched cohort

2020 ◽  
Vol 72 (3) ◽  
pp. 910-917 ◽  
Author(s):  
Slobodan Cvetkovic ◽  
Igor Koncar ◽  
Stefan Ducic ◽  
Petar Zlatanovic ◽  
Perica Mutavdzic ◽  
...  
Keyword(s):  
Propensity Score ◽  
Open Repair ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Long Term Results ◽  
Matched Cohort ◽  
Abdominal Aortic

scholarly journals Outcome after open and endovascular repairs of abdominal aortic aneurysms in matched cohorts using propensity score modeling

2015 ◽  
Vol 62 (2) ◽  
pp. 304-311.e2 ◽  
Author(s):  
Ying Huang ◽  
Peter Gloviczki ◽  
Gustavo S. Oderich ◽  
Audra A. Duncan ◽  
Manju Kalra ◽  
...  
Keyword(s):  
Propensity Score ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

Multiyear Square Dancing Is Associated With Superior Mental Processing Capacity But Not Memory in Middle-Aged and Older Chinese Women: A Cross-Sectional Propensity Score Matching Analysis

2020 ◽  
Vol 17 (7) ◽  
pp. 736-743
Author(s):  
Jing Liao ◽  
Yung-Jen Yang ◽  
Dong (Roman) Xu
Keyword(s):  
Physical Activity ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Social Engagement ◽  
Chinese Women ◽  
Social Activity ◽  
Positive Association ◽  
Processing Capacity ◽  
Cross Sectional ◽  
Propensity Score Matching Analysis

Background: Evidence suggests the importance of physical activity and social engagement in cognitive preservation. Group-based dancing combining exercise and prosocial features may generate physical and cognitive benefits. Objectives: To investigate the association between multiyear habitual square dancing and domain-specific cognitive function, and assess the relative importance and joint impact of physical activity and social activity on cognition. Methods: Using the cross-sectional propensity score matching method, the study compared the mental status, episodic memory, and overall cognitive performances of 145 amateur female square-dancing participants (aged ≥45 y) to their sociodemographic- and health-status–matched 222 nondancing counterparts, selected from the China Health and Retirement Longitudinal Study. Results: The authors found a positive association between multiyear square dancing (average 8 y) and overall cognitive performances (mean difference = 2.84; 95% confidence interval [CI], 1.65 to 4.02), which was apparent in processing capacity (2.29; 95% CI, 1.51 to 3.07) but not in memory (0.55; 95% CI, −0.13 to 1.23). The hypothesized synergic effect of physical activity and social activity on cognition was only observed in group-based exercises embodying these 2 components simultaneously. Conclusions: Long-term square dancing as one type of physically and socially engaging activities may preserve cognition. Future longitudinal and interventional studies are needed to further clarify the causal relationship.

Aortic Lumen Area Is Increased in Ruptured Abdominal Aortic Aneurysms and Correlates to Biomechanical Rupture Risk

2018 ◽  
Vol 25 (6) ◽  
pp. 750-756 ◽  
Author(s):  
Antti Siika ◽  
Moritz Lindquist Liljeqvist ◽  
Rebecka Hultgren ◽  
T. Christian Gasser ◽  
Joy Roy
Keyword(s):  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Maximum Diameter ◽  
Patient Specific ◽  
Lumen Area ◽  
Rupture Risk ◽  
Cross Sectional ◽  
Vessel Area ◽  
Abdominal Aortic ◽  
Risk Parameters

Purpose: To investigate how 2-dimensional geometric parameters differ between ruptured and asymptomatic abdominal aortic aneurysms (AAAs) and provide a biomechanical explanation for the findings. Methods: The computed tomography angiography (CTA) scans of 30 patients (mean age 77±10 years; 23 men) with ruptured AAAs and 60 patients (mean age 76±8 years; 46 men) with asymptomatic AAAs were used to measure maximum sac diameter along the center lumen line, the cross-sectional lumen area, the total vessel area, the intraluminal thrombus (ILT) area, and corresponding volumes. The CTA data were segmented to create 3-dimensional patient-specific models for finite element analysis to compute peak wall stress (PWS) and the peak wall rupture index (PWRI). To reduce confounding from the maximum diameter, 2 diameter-matched groups were selected from the initial patient cohorts: 28 ruptured AAAs and another with 15 intact AAAs (diameters 74±12 vs 73±11, p=0.67). A multivariate model including the maximum diameter, the lumen area, and the ILT area of the 60 intact aneurysms was employed to predict biomechanical rupture risk parameters. Results: In the diameter-matched subgroup comparison, ruptured AAAs had a significantly larger cross-sectional lumen area (1954±1254 vs 1120±623 mm2, p=0.023) and lower ILT area ratio (55±24 vs 68±24, p=0.037). The ILT area (2836±1462 vs 2385±1364 mm2, p=0.282) and the total vessel area (3956±1170 vs 4338±1388 mm2, p=0.384) did not differ statistically between ruptured and intact aneurysms. The PWRI was increased in ruptured AAAs (0.80 vs 0.48, p<0.001), but the PWS was similar (249 vs 284 kPa, p=0.194). In multivariate regression analysis, lumen area was significantly positively associated with both PWS (p<0.001) and PWRI (p<0.01). The ILT area was also significantly positively associated with PWS (p<0.001) but only weakly with PWRI (p<0.01). The lumen area conferred a higher risk increase in both PWS and PWRI when compared with the ILT area. Conclusion: The lumen area is increased in ruptured AAAs compared to diameter-matched asymptomatic AAAs. Furthermore, this finding may in part be explained by a relationship with biomechanical rupture risk parameters, in which lumen area, irrespective of maximum diameter, increases PWS and PWRI. These observations thus suggest a possible method to improve prediction of rupture risk in AAAs by measuring the lumen area without the use of computational modeling.

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