Multiyear Square Dancing Is Associated With Superior Mental Processing Capacity But Not Memory in Middle-Aged and Older Chinese Women: A Cross-Sectional Propensity Score Matching Analysis

2020 ◽  
Vol 17 (7) ◽  
pp. 736-743
Author(s):  
Jing Liao ◽  
Yung-Jen Yang ◽  
Dong (Roman) Xu

Background: Evidence suggests the importance of physical activity and social engagement in cognitive preservation. Group-based dancing combining exercise and prosocial features may generate physical and cognitive benefits. Objectives: To investigate the association between multiyear habitual square dancing and domain-specific cognitive function, and assess the relative importance and joint impact of physical activity and social activity on cognition. Methods: Using the cross-sectional propensity score matching method, the study compared the mental status, episodic memory, and overall cognitive performances of 145 amateur female square-dancing participants (aged ≥45 y) to their sociodemographic- and health-status–matched 222 nondancing counterparts, selected from the China Health and Retirement Longitudinal Study. Results: The authors found a positive association between multiyear square dancing (average 8 y) and overall cognitive performances (mean difference = 2.84; 95% confidence interval [CI], 1.65 to 4.02), which was apparent in processing capacity (2.29; 95% CI, 1.51 to 3.07) but not in memory (0.55; 95% CI, −0.13 to 1.23). The hypothesized synergic effect of physical activity and social activity on cognition was only observed in group-based exercises embodying these 2 components simultaneously. Conclusions: Long-term square dancing as one type of physically and socially engaging activities may preserve cognition. Future longitudinal and interventional studies are needed to further clarify the causal relationship.

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Zhiqiang Zhao ◽  
Chunmei Gong ◽  
Yanfang Gao ◽  
Xiaoli Liu ◽  
Sai Wu ◽  
...  

Cardiovascular development critical genes are key determinants in cardiovascular diseases. We hypothesize that SNPs in these genes may play critical roles in the development of hypertension. Therefore, we enrolled 516 paired hypertension patients and controls in a total of 2,742 subjects in a cross-sectional population study by the propensity score matching (PSM) method. Twenty-one SNPs from 5 cardiovascular developmental related genes were detected by the improved multiplex ligase detection reaction (iMLDR) method. Conditioned logistic regression under three different genetic models, namely, additive model, dominant model, and recessive model, was performed. The odds ratio (ORs) and 95% confidence intervals (95% CIs) were used to estimate the associations of SNPs with hypertension. We found that the distribution of genotypes at rs833061, rs3025010, and rs699947 within the VEGFA gene and the distribution of alleles at rs3025010 in hypertension subjects were different from those in controls. Both rs833061 and rs3025010 were associated with hypertension in crude models, but only rs3025010 remains associated with hypertension after adjusting with confounding factors in the additive model and the dominant model. We also found that hypertension subjects with C/T and C/C genotypes at rs3025010 had lower SBP and DBP levels. In addition, rs3025010 could interact with rs6784267 within the CCM3 gene in the association. In conclusion, our findings suggest that rs3025010 may play a role in the pathogenesis of hypertension, which may be a potential target for individualized prevention and treatment of hypertension.


2015 ◽  
Vol 9 ◽  
pp. CMC.S23166 ◽  
Author(s):  
Takao Kato ◽  
Seiko Ishida ◽  
Shoichi Miyamoto ◽  
Tamae Iura ◽  
Yoko Ban ◽  
...  

Introduction We previously reported that the prevalence of abdominal aortic aneurysms (AAAs) was higher in patients undergoing scheduled transthoracic echocardiography (TTE) than in patients undergoing abdominal ultrasonography (AUS); however, intergroup patient backgrounds differed significantly in that report. Purpose We tested the hypothesis that TTE could detect AAA as effectively as AUS. Design A propensity score-matching analysis of a cross-sectional study was adopted as the design for this study. Methods We enrolled 7,619 and 15,433 patients scheduled to undergo TTE with additional evaluation of abdominal aorta at the end of the routine study and AUS, respectively, from 2009 to 2010 in our hospital, as reported. A propensity score for profiles of patients who underwent TTE or AUS was developed to adjust for potential confounding bias. Consequently, 4,388 patients in each group were matched for analyses. Results In propensity-matched patients, AAA was detected in 59 patients of the TTE group and in 48 patients of the AUS group; the prevalence of AAA detection did not differ significantly between TTE and AUS groups ( P = 0.331). Positive associations were observed between AAA detection and male sex (adjusted odds ratio [OR]: 3.25; 95% confidence interval [CI], 2.05-5.15; P < 0.001), older age (adjusted OR: 1.029; 95% CI: 1.01-1.04; P < 0.001), and the presence of ischemic heart disease (adjusted OR: 1.78; 95% CI: 1.04-3.03; P = 0.033) and hypertension (adjusted OR: 2.16; 95% CI: 1.38-3.37; P = 001). Conclusion TTE detected AAA with comparable efficacy as AUS in propensity-matched groups who underwent scheduled TTE and AUS.


2021 ◽  
Author(s):  
Xinlin Chen ◽  
Dai Su ◽  
Xinlan Chen ◽  
Yingchun Chen

Abstract Background The strategy of successful ageing is an important means to deal with the challenges of the current ageing society. This paper aims to explore the effects of different intensities of physical activity on the successful ageing of the elderly. Methods Our data were from wave 4 of the China Health and Retirement Longitudinal Survey (CHARLS), involving 9,026 residents aged 60 years and older. The intensity of physical activity was divided into three levels: vigorous, moderate and mild. The concept of successful ageing adopted a four-dimensional model of life satisfaction added to the theoretical model of Rowe and Kahn's. Propensity score matching (PSM) with controlling nine confounding factors were used to analyse the effects of different intensities of physical activity. Results The percentage of successful ageing was 1.88% among all subjects. Among them, 30.26%, 29.57% and 29.40% of the elderly often participated in vigorous, moderate and mild physical activity, respectively. The results of PSM showed that participation in moderate activity increased the probability of successful ageing of the elderly by 0.76–0.78% (P < 0.001), while participation in vigorous and mild physical activity had no significant effect on successful ageing (P > 0.05). Conclusion Moderate-intensity physical activity was most beneficial to the successful ageing of the elderly and should be promoted in the elderly population.


Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
YuSung Lee ◽  
YoungSun Ro ◽  
KyoungJun Song ◽  
SangDo Shin

Background: Although prehospital epinephrine is frequently used in patients with out-of-hospital cardiac arrest (OHCA), its evidence is unclear. Recent studies have shown that the use of prehospital epinephrine increased the rate of return of spontaneous circulation but has a negative impact on outcomes. The aim of this study was to investigate the effect of prehospital epinephrine on the outcomes of OHCA. Methods: This study was a cross-sectional study using nationwide OHCA registry in Korea from 2015 to 2016. All EMS-treated adults OHCAs with presumed cardiac etiology were included. Patients who were witnessed by EMS provider were excluded. The primary outcome was neurologically favorable survival to discharge. We compared the primary outcomes between the prehospital epinephrine group and non-prehospital epinephrine group using a propensity score matching analysis and a multivariable logistic regression. Results: Among 58922 patients with OHCA, 37635 were included in the analysis. There were 3256 patients who received prehospital epinephrine. In the propensity score matching analysis, 3239 patients were enrolled in each group. Survival to discharge and good neurologic recovery were 5.0% and 2.5% in prehospital epinephrine group and 9.4% and 5.9% in non-prehospital epinephrine group (all p-value<o.o1). There was significant difference in good neurologic recovery between prehospital epinephrine group and non-prehospital epinephrine group after adjusting for covariates (adjusted OR, 0.38, 95% CI, 0.28-0.51). Similar results were observed for survival to discharge (adjusted OR, 0.47, 95% CI, 0.38-0.58). Conclusions: In Korean patients with OHCA, prehospital epinephrine increased the probability of ROSC, but decreased good neurologic recovery and survival to discharge.


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