Temporal changes in milk conjugated linoleic acidfor cows fed a pasture- or conserved-forages-based diet and supplemented with fish oil and sunflower oil

2008 ◽  
Vol 88 (1) ◽  
pp. 123-127
Author(s):  
D. O. Felton ◽  
S. A. Ibrahim ◽  
A. A. AbuGhazaleh

The objective of this experiment was to evaluate the effect of forage source on the temporal changes in milk conjugated linoleic acid (CLA). Fourteen Holstein cows were divided into two groups. One group (LOT) was fed a corn silage-alfalfa hay mix ad libitum, while the other group (PAS) grazed on alfalfa-grass pasture. Additionally, both groups were fed 8.2 kg d-1 grain supplement containing 650 g of oil composed of fish oil and sunflower oil (1:4). The concentration of cis-9, trans-11 CLA in milk fat of both diets reached maximum levels on day 3 of oil supplementation, declined during day 6, and then remained constant during the reminder of the experiment. Milk vaccenic acid (VA) and trans-10 C18:1 reached their maximum concentrations on days 3 and 6, respectively, of oil supplementation with both diets. In conclusion, the decline in milk cis-9, trans-11 CLA over time was not affected by forage source and may have resulted from an increase in formation of trans-10 C18:1 and C18:0 at the expenses of VA. Key words: Conjugated linoleic acid, milk, forage, fish oil, sunflower oil

2007 ◽  
Vol 90 (8) ◽  
pp. 3786-3801 ◽  
Author(s):  
C. Cruz-Hernandez ◽  
J.K.G. Kramer ◽  
J.J. Kennelly ◽  
D.R. Glimm ◽  
B.M. Sorensen ◽  
...  

2000 ◽  
Vol 83 (11) ◽  
pp. 2620-2628 ◽  
Author(s):  
D.C. Donovan ◽  
D.J. Schingoethe ◽  
R.J. Baer ◽  
J. Ryali ◽  
A.R. Hippen ◽  
...  

2014 ◽  
Vol 36 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Sergio I. Martínez-Monteagudo ◽  
Mohamed Khan ◽  
Feral Temelli ◽  
Marleny D.A. Saldaña

2005 ◽  
Vol 289 (2) ◽  
pp. H652-H659 ◽  
Author(s):  
Karine Valeille ◽  
Jacqueline Férézou ◽  
Ghislaine Amsler ◽  
Annie Quignard-Boulangé ◽  
Michel Parquet ◽  
...  

Conjugated linoleic acid (CLA) mixtures demonstrated antiatherogenic properties in several animal models, including hamsters, but the mechanism of action of the main food-derived CLA isomer is unknown in this species. This study thus focused on cis-9, trans-11-CLA (rumenic acid), and its effect was compared with that of fish oil, which is known to influence several aspects of atherogenesis. Syrian hamsters were fed (for 12 wk) diets containing 20% (wt/wt) butter fat (B diet) or the same diet augmented with either 1% (wt/wt) of a cis-9, trans-11-CLA-rich oil (BR diet) or 1% (wt/wt) fish oil (BF diet). The BR diet induced the lowest aortic lipid deposition (from −30% to −45%) among the butter oil-fed hamsters. In this group, plasma also displayed a reduced non-HDL-to-HDL-cholesterol ratio (21% less than in the butter oil group) and inflammatory serum amyloid A levels (70–80%) and an improvement of anti-oxidized LDL paraoxonase activity (all P < 0.05). Compared with the B group, the beneficial effects of the BR diet could be further explained in part by preventing the high VCAM-1 expression rate, increasing (30%) ATP-binding cassette subfamily A1 expression in the aorta, and downregulating expression of inflammatory-related genes (TNF-α, IL-1β, and cyclooxygenase 2, 2- to 2.8-fold, P < 0.05). This effect was partly associated with an activation of peroxisome proliferator-activating receptor (PPAR)/liver X receptor (LXR)-α signaling cascade. Interestingly, activation of PPAR/LXR-α signaling was not observed in hamsters fed the BF diet, in which the early signs of atherogenesis were increased. In conclusion, this study demonstrated that milk fat-rich cis-9, trans-11-CLA reduces the atherogenic process in hyperlipidemic hamsters.


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