scholarly journals Dietary carnosic acid suppresses hepatic steatosis formation via regulation of hepatic fatty acid metabolism in high-fat diet-fed mice

2013 ◽  
Vol 7 (4) ◽  
pp. 294 ◽  
Author(s):  
Mi-Young Park ◽  
Seong Taek Mun
Keyword(s):  
Fatty Acid ◽  
Hepatic Steatosis ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
Carnosic Acid ◽  
High Fat ◽  
Hepatic Fatty Acid

Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats

2011 ◽  
Vol 1811 (7-8) ◽  
pp. 441-451 ◽  
Author(s):  
Jolita Ciapaite ◽  
Nicole M. van den Broek ◽  
Heleen te Brinke ◽  
Klaas Nicolay ◽  
Jeroen A. Jeneson ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
High Fat ◽  
Differential Effects ◽  
Hepatic Fatty Acid ◽  
Short And Long Term

Ingested cocoa can prevent high-fat diet-induced obesity by regulating the expression of genes for fatty acid metabolism

Nutrition ◽  
2005 ◽  
Vol 21 (5) ◽  
pp. 594-601 ◽  
Author(s):  
Naoko Matsui ◽  
Ryoichi Ito ◽  
Eisaku Nishimura ◽  
Mariko Yoshikawa ◽  
Masatoshi Kato ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Expression Of Genes

scholarly journals EGCG regulates fatty acid metabolism of high-fat diet-fed mice in association with enrichment of gut Akkermansia muciniphila

2020 ◽  
Vol 75 ◽  
pp. 104261
Author(s):  
Xiaoxia Liu ◽  
Ke Zhao ◽  
Nana Jing ◽  
Yan Zhao ◽  
Xingbin Yang
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
High Fat ◽  
Akkermansia Muciniphila

scholarly journals Effects of Xanthohumol-rich Extract from the Hop on Fatty Acid Metabolism in Rats Fed a High-fat Diet

2014 ◽  
Vol 63 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Kazuki Yui ◽  
Ayane Kiyofuji ◽  
Kyoichi Osada
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
High Fat

scholarly journals Pu-erh Tea Regulates Fatty Acid Metabolism in Mice Under High-Fat Diet

2019 ◽  
Vol 10 ◽  
Author(s):  
Fengjie Huang ◽  
Shouli Wang ◽  
Aihua Zhao ◽  
Xiaojiao Zheng ◽  
Yunjing Zhang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
High Fat

scholarly journals Maternal High-Fat-Diet Programs Rat Offspring Liver Fatty Acid Metabolism

Lipids ◽  
2015 ◽  
Vol 50 (6) ◽  
pp. 565-573 ◽  
Author(s):  
Emily L. Seet ◽  
Jennifer K. Yee ◽  
Juanita K. Jellyman ◽  
Guang Han ◽  
Michael G. Ross ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
Liver Fatty Acid ◽  
High Fat ◽  
Rat Offspring

scholarly journals Effect of the prolonged high-fat diet on the fatty acid metabolism in rat blood and liver

2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Natalia V Zhukova ◽  
Tatyana P Novgorodtseva ◽  
Yulia K Denisenko
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
High Fat Diet ◽  
Acid Metabolism ◽  
High Fat ◽  
Rat Blood

scholarly journals A Model Construction of Starvation Induces Hepatic Steatosis and Transcriptome Analysis in Zebrafish Larvae

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 92
Author(s):  
Hao Xu ◽  
Yu Jiang ◽  
Xiao-Min Miao ◽  
Yi-Xi Tao ◽  
Lang Xie ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Hepatic Steatosis ◽  
Fatty Acid Metabolism ◽  
Transcriptome Analysis ◽  
Acid Metabolism ◽  
Fatty Acid Uptake ◽  
Acid Uptake ◽  
Alcoholic Fatty Liver ◽  
Zebrafish Larvae ◽  
Hepatic Fatty Acid

Hepatic steatosis caused by starvation, resulting in non-alcoholic fatty liver disease (NAFLD), has been a research topic of human clinical and animal experiments. To understand the molecular mechanisms underlying the triggering of abnormal liver metabolism by starvation, thus inducing hepatic lipid accumulation, we used zebrafish larvae to establish a starvation-induced hepatic steatosis model and conducted comparative transcriptome analysis by RNA-seq. We demonstrated that the incidence of larvae steatosis is positively correlated with starvation time. Under starvation conditions, the fatty acid transporter (slc27a2a and slc27a6-like) and fatty acid translocase (cd36) were up-regulated significantly to promote extrahepatic fatty acid uptake. Meanwhile, starvation inhibits the hepatic fatty acid metabolism pathway but activates the de novo lipogenesis pathway to a certain extent. More importantly, we detected that the expression of numerous apolipoprotein genes was downregulated and the secretion of very low density lipoprotein (VLDL) was inhibited significantly. These data suggest that starvation induces hepatic steatosis by promoting extrahepatic fatty acid uptake and lipogenesis, and inhibits hepatic fatty acid metabolism and lipid transport. Furthermore, we found that starvation-induced hepatic steatosis in zebrafish larvae can be rescued by targeting the knockout cd36 gene. In summary, these findings will help us understand the pathogenesis of starvation-induced NAFLD and provide important theoretical evidence that cd36 could serve as a potential target for the treatment of NAFLD.

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