Fluorescent dye copolymerized silica nanoparticles for analytical applications

2018 ◽  
Vol 09 ◽  
Author(s):  
Gabor Patonay
2018 ◽  
Vol 6 (2) ◽  
pp. 022002 ◽  
Author(s):  
Enrico Rampazzo ◽  
Damiano Genovese ◽  
Francesco Palomba ◽  
Luca Prodi ◽  
Nelsi Zaccheroni

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3802
Author(s):  
Aleksandr A. Goncharenko ◽  
Ilya A. Tarasyuk ◽  
Yuriy S. Marfin ◽  
Kirill V. Grzhegorzhevskii ◽  
Albert R. Muslimov ◽  
...  

The design of cargo carriers with high biocompatibility, unique morphological characteristics, and capability of strong bonding of fluorescent dye is highly important for the development of a platform for smart imaging and diagnostics. In this paper, BODIPY-doped silica nanoparticles were prepared through a “one-pot” soft-template method using a sol-gel process. Several sol-gel precursors have been used in sol-gel synthesis in the presence of soft-template to obtain the silica-based materials with the most appropriate morphological features for the immobilization of BODIPY molecules. Obtained silica particles have been shown to be non-cytotoxic and can be effectively internalized into the cervical cancer cell line (HeLa). The described method of synthesis allows us to obtain silica-based carriers with an immobilized fluorescent dye that provide the possibility for real-time imaging and detection of these carriers.


2013 ◽  
Vol 796 ◽  
pp. 424-427
Author(s):  
Chuan Xiang Qin ◽  
Lin Qin ◽  
Guo Qiang Chen ◽  
Tong Lin

Trans-4- [p- (N, N-Die (2-hydroxyethyl)) styry-N-ethyl pyridinium bromide (DHEASPBr-C2), a hemicyanine fluorescent dye, was encapsulated into silica nanoparticles by co-hydrolysis and co-condensation of organosilanes in the presence of the dye. The dye containing silica nanoparticles were applied onto cotton fabrics. Scanning electron microscopy (SEM), UVvis spectra, single-photon emission fluorescence spectra and reflectance spectra of the samples were characterized. The SEM results showed that the particle size (ranging from 100-200 nm) and dye encapsulating (1.5-8.1 mg dye per g silica matrix) could be adjusted by the concentration of fluorescent dye and organosilanes. The reflectance of the treated cotton fabrics showed that there were obvious adsorption spectra in 410 - 540 nm and emission spectra in 560 - 700 nm.


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