Coarctation of the aorta undiagnosed early postpartum risk factor for sudden death in pregnancy

2011 ◽  
Vol 01 (S1) ◽  
Author(s):  
Manuela Stoicescu
Keyword(s):  
Risk Factor ◽  
Sudden Death ◽  
Coarctation Of The Aorta ◽  
Early Postpartum ◽  
In Pregnancy

scholarly journals Evaluation of blood type as a potential risk factor for early postpartum hemorrhage

PLoS ONE ◽  
2019 ◽  
Vol 14 (4) ◽  
pp. e0214840 ◽  
Author(s):  
Mais Ali-Saleh ◽  
Ofer Lavie ◽  
Yoram Abramov
Keyword(s):  
Risk Factor ◽  
Potential Risk ◽  
Postpartum Hemorrhage ◽  
Potential Risk Factor ◽  
Blood Type ◽  
Early Postpartum

scholarly journals Uncontrolled maternal chronic respiratory diseases in pregnancy: A new potential risk factor suggested to be associated with anorectal malformations in offspring

2018 ◽  
Vol 111 (2) ◽  
pp. 62-69 ◽  
Author(s):  
Romy van de Putte ◽  
Ivo de Blaauw ◽  
Rianne Boenink ◽  
Monique H.E. Reijers ◽  
Paul M.A. Broens ◽  
...  
Keyword(s):  
Risk Factor ◽  
Potential Risk ◽  
Respiratory Diseases ◽  
Anorectal Malformations ◽  
Potential Risk Factor ◽  
Chronic Respiratory Diseases ◽  
In Pregnancy

scholarly journals Viral and antiretroviral dynamics in HIV mother-to-child transmission fluids (VADICT) – Protocol and data analysis plan for a cohort study

2019 ◽  
Vol 4 ◽  
pp. 34
Author(s):  
Adeniyi Olagunju ◽  
Damien Anweh ◽  
Ogechi Okafor ◽  
Laura Dickinson ◽  
Douglas Richman ◽  
...  
Keyword(s):  
Drug Disposition ◽  
Population Pharmacokinetic ◽  
Mother To Child Transmission ◽  
Sample Collection ◽  
Child Transmission ◽  
Link Type ◽  
Early Postpartum ◽  
Mother To Child ◽  
Hiv 1 ◽  
In Pregnancy

Background: Pregnancy and polymorphisms in drug disposition genes alter the clearance of key antiretrovirals used as part of regimens for prevention of mother-to-child transmission of HIV (PMTCT). The clinical significance of these in women initiating therapy late in pregnancy has not been investigated. The primary objective of the Viral and Antiretroviral Dynamics in HIV Mother-To-Child Transmission Fluids (VADICT) study is to investigate viral and antiretroviral dynamics in matrices associated with mother-to-child transmission (MTCT) (plasma, genital fluid and breastmilk) in women (stratified by CYP2B6 genotypes) who initiate antiretroviral therapy (ART) before or early in pregnancy versus late in pregnancy or early postpartum. Methods: A cohort of HIV-1 infected women who initiated ART containing 600 mg efavirenz before or early in pregnancy (n = 120), during the third trimester (n = 60), or early postpartum (n = 60) will be studied.  Eligible patients will be recruited from four hospitals in Benue State, North Central Nigeria and followed until the end of breastfeeding. Procedures at follow up visits will include sample collection for drug quantification and HIV-1 RNA and DNA in plasma, genital fluid and breastmilk; adherence monitoring; and newborn and infant assessment. Using newborn exposure to maternal efavirenz at birth for validation, prenatal pharmacogenetics of efavirenz will be explored using physiologically-based pharmacokinetic modelling. Three integrated methods will be used to monitor patterns and correlates of adherence across pregnancy and the breastfeeding period. A population pharmacokinetic-pharmacodynamic model will be developed to describe the observed data and simulate what to expect in women initiating ART containing 400 mg efavirenz (recently approved for non-pregnant adults) late in pregnancy or early postpartum. Discussion: This study will help in understanding residual MTCT in women receiving ART and reasons for the rise in MTCT risk during the breastfeeding period. Trial registration: ClinicalTrials.gov: NCT03284645 (15/09/2017)

Mild gestational hyperglycaemia as a risk factor for metabolic syndrome in pregnancy and adverse perinatal outcomes

2008 ◽  
Vol 24 (4) ◽  
pp. 324-330 ◽  
Author(s):  
Carlos Antonio Negrato ◽  
Lois Jovanovic ◽  
Marcos Antonio Tambascia ◽  
Iracema de Mattos Paranhos Calderon ◽  
Bruno Geloneze ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
Perinatal Outcomes ◽  
Adverse Perinatal Outcomes ◽  
In Pregnancy

Coarctation of the aorta A risk factor in children for the development of arteriosclerosis

1981 ◽  
Vol 39 (3) ◽  
pp. 367-381 ◽  
Author(s):  
E. Anyanwu ◽  
H. Dittrich ◽  
V. Jelesijević ◽  
B. Drüen ◽  
E.R. Krefting ◽  
...  
Keyword(s):  
Risk Factor ◽  
Coarctation Of The Aorta

scholarly journals Varices of the round ligament mimicking an inguinal hernia – an important differential diagnosis during pregnancy

2010 ◽  
Vol 92 (7) ◽  
pp. e10-e11 ◽  
Author(s):  
BM Dent ◽  
A Al Samaraee ◽  
PE Coyne ◽  
C Nice ◽  
M Katory
Keyword(s):  
Differential Diagnosis ◽  
Risk Factor ◽  
Inguinal Hernia ◽  
Pregnant Women ◽  
Clinical Examination ◽  
Abdominal Pressure ◽  
Emergency Repair ◽  
Important Differential Diagnosis ◽  
Ultrasound Evaluation ◽  
In Pregnancy

Pregnancy is a recognised risk factor for the development of inguinal hernias due to an increase in intra-abdominal pressure. Whilst often managed conservatively until after the pregnancy, if the hernia presents acutely as a painful or tender groin lump, urgent or emergency repair may be required. Many clinicians rely heavily on clinical examination alone in order to diagnose the presence of such a hernia. In pregnancy, however, in order to prevent unnecessary surgery, the use of ultrasound has a more important role to play in reaching this diagnosis. We report a cautionary case that highlights the need for ultrasound evaluation of all painful groin lumps in pregnant women prior to considering surgery.

P2244Anomalies in women of the aortic arch in Turner syndrome as an important risk factor for premature morbidity and mortality

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
E Klaskova ◽  
S Kapralova ◽  
J Zapletalova ◽  
Z Tudos ◽  
K Adamova
Keyword(s):  
Risk Factor ◽  
Aortic Arch ◽  
Cell Line ◽  
Turner Syndrome ◽  
Subclavian Artery ◽  
X Chromosome ◽  
Coarctation Of The Aorta ◽  
Aberrant Right Subclavian Artery ◽  
Structural Abnormality ◽  
Study Group

Abstract Introduction Turner syndrome (TS) represents the most common chromosomal disorder in women being, caused by the absence or structural abnormality of X chromosome. Congenital heart defects affect up to 50% of females with TS.Prevalence of coarctation of the aorta in TS has been estimated 7–18% depending on imaging method. Introduction of cardiac magnetic resonance imaging (MRI) into the routine practice markedly increased the detection rate of anomalies of the aortic arch such as elongated transverse aortic arch with abnormal curvature, i.e.kinking, pseudocoarctation or aberrant right subclavian artery. Aims of study was to estimate prevalence of anomalies of the aortic arch in our study group according to the karyotype. Methods and patients Study group consisted of 67 patients with TS at the age 7.3 yrs (range 0.1 - 16.5 yrs.). Complete cardiovascular examination (echocardiography, MRI of the heart and great vessels) and cytogenetic examination were performed in each of our study patient. Results The prevalence of anomalies of the aortic arch was 15% (10 patients). Four of them had elongated transverse aortic, coarctation of the aorta was found in three cases, aberrant right subclavian artery in two patients and one girl had right aortic arch. 45,X cell line was presented in every patient with anomaly of the aortic arch, none of them had structural abnormality of X chromosome. Conclusions Compared with the general population, the prevalence of CoA and the others anomalies of the aortic arch is significantly higher in women with TS, especially with 45,X cell line. As far as CoA is considered to be one of the major risk factor for aortic dissection detailed cardiovascular screening focused on thoracic aorta anomalies seems to be crucial in order to prevent it. Acknowledgement/Funding Supported by Ministry of Health, Czech Republic - MZ VES 2017 (Reg. No. NV17-29111A).

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