scholarly journals Computational Modeling of Blast Induced Human Injury Biomechanics and Traumatic Brain Injury

2017 ◽  
Vol 06 (05) ◽  
Author(s):  
Gary Tan X ◽  
Andrzej J Przekwas ◽  
Raj K Gupta
Neurotrauma ◽  
2018 ◽  
pp. 347-358
Author(s):  
Michelle C. LaPlaca

The study of traumatic brain injury (TBI) encompasses research spanning from injury prevention to clinical interventions, all of which have been influenced by bioengineering. Bioengineering uses quantitative analyses and problem-solving skills to approach the complexity of many areas of neurotrauma research including injury biomechanics, imaging, biomarkers, and data analytics. This chapter presents basic bioengineering concepts, highlights significant contributions to neurotrauma research, and discusses opportunities in the field that may lend themselves to bioengineering solutions. The intention of the author is to promote an appreciation of engineering and to catalyze problem-solving among readers, engineers and non-engineers alike.


Author(s):  
Jiangyue Zhang ◽  
Narayan Yoganandan ◽  
Frank A. Pintar ◽  
Steven F. Son ◽  
Thomas A. Gennarelli

Traumatic brain injury from explosive devices has become the signature wound of the U.S. armed forces in Iraq and Afghanistan [1–4]. However, due to the complicated nature of this specific form of brain injury, little is known about the injury mechanisms. Physical head models have been used in blunt and penetrating head trauma studies to obtain biomechanical data and correlate to mechanisms of injury [5–8]. The current study is designed to investigate intracranial head/brain injury biomechanics under blast loading using a physical head model.


2000 ◽  
Author(s):  
Kiyoshi Omori ◽  
Liying Zhang ◽  
King H. Yang ◽  
Albert I. King

Abstract Traumatic brain injury (TBI) constitutes a significant portion of all injuries occurring as a result of automotive, motorcycle and sports related injuries. Over the years, a large amount of literature has been devoted to an increased understanding of clinical symptoms, pathological evidence and injury biomechanics for such injuries. However, the precise causal mechanism, which accounts for complex mechanical interactions and responses in an anatomical structure as complex as the brain, is not fully understood.


2021 ◽  
Vol 15 ◽  
Author(s):  
Frederick J. Gallun

Despite over 100 years of study, there are still many fundamental questions about binaural hearing that remain unanswered, including how impairments of binaural function are related to the mechanisms of binaural hearing. This review focuses on a number of studies that are fundamental to understanding what is known about the effects of peripheral hearing loss, aging, traumatic brain injury, strokes, brain tumors, and multiple sclerosis (MS) on binaural function. The literature reviewed makes clear that while each of these conditions has the potential to impair the binaural system, the specific abilities of a given patient cannot be known without performing multiple behavioral and/or neurophysiological measurements of binaural sensitivity. Future work in this area has the potential to bring awareness of binaural dysfunction to patients and clinicians as well as a deeper understanding of the mechanisms of binaural hearing, but it will require the integration of clinical research with animal and computational modeling approaches.


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