scholarly journals Effectiveness of hydrogen peroxide as auxiliary treatment for COVID-19 hospitalized patients - preliminary results of a randomized double-blind clinical trial

2021 ◽  
pp. e2021032
Author(s):  
Marielle Bazzo Di Domênico ◽  
Henrique Cesca ◽  
Thales Henrique Jincziwski Ponciano ◽  
Renan Brandenburg dos Santos ◽  
Ulysses Lenz ◽  
...  
2021 ◽  
pp. 108227
Author(s):  
Hanieh Azizi ◽  
Nima Rouhani ◽  
Fatemeh Shaki ◽  
Elahe Karimpour-razkenari ◽  
Monireh Ghazaeian ◽  
...  

1975 ◽  
Vol 3 (3) ◽  
pp. 153-157 ◽  
Author(s):  
F Michot ◽  
K Ajdacic ◽  
L Glaus

A double-blind crossover trial between diclofenac sodium and placebo was carried out in 32 hospitalized patients who were thought to be stabilized on concurrent anticoagulant therapy with acenocoumarol. The object of the trial was to investigate any possible interaction between diclofenac and anticoagulant by monitoring prothrombin times daily through the four week period. No statistically significant difference between placebo and diclofenac could be shown and some problems of accurately monitoring prothrombin times are discussed.


2019 ◽  
Vol 13 (1) ◽  
pp. 377-382
Author(s):  
Leandro Féliz-Matos ◽  
Ninoska Abreu-Placeres ◽  
Luis Miguel Hernandez ◽  
Carlos Ruiz-Matuk ◽  
Patricia Grau-Grullón

Background: The clinical evidence relate the effect of associating the in-office and at home vital tooth whitening, describing positive effects on tooth color change and reduction of dental sensitivity. Objective: The purpose of this randomized double-blind clinical trial was to evaluate the effect on the shortened application of in-office vital tooth whitening combined with different concentrations of at-home peroxides in the final tooth color change and dental sensitivity. Methods: Randomized double-blind clinical trial with 120 participants between 18-65 years, allocated in four tooth whitening treatment groups: G1= Carbamide Peroxide 10% + Hydrogen Peroxide 40%, G2= Carbamide Peroxide 15% + Hydrogen Peroxide 40%, G3= Carbamide Peroxide 20% + Hydrogen Peroxide 40%, G4= Hydrogen Peroxide 10% + Hydrogen Peroxide 40% was conducted. Tooth color was measured at baseline and dental sensitivity and tooth color change during and after treatment. Results: No statistical significant differences were found in tooth color change (superior arch p= 0.183 / inferior arch p= 0.374), and in dental sensitivity (p=0.268). Conclusion: Reducing the application time of in-office whitening, combined with in-home products was effective in improving the color. All groups resulted in identical final color change and dental sensitivity. Clinicaltrials.gov: NCT02682329 Available from: https://clinicaltrials.gov/ct2/show/NCT02682329?term=hydrogen+peroxide.


2021 ◽  
pp. e2021051
Author(s):  
Marielle Bazzo Di Domênico ◽  
Kauê Collares ◽  
Renan Brandenburg dos Santos ◽  
Ulysses Lenz ◽  
Vinícius Picoli Antunes ◽  
...  

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