scholarly journals Assessment of drug therapy problem and associated factors among adult hypertensive patients at Ayder comprehensive specialized hospital, Northern Ethiopia

2019 ◽  
Vol 19 (3) ◽  
pp. 2571-2579
Author(s):  
Asgedom Solomon Weldegebreal ◽  
Fekadu Tezeta ◽  
Atey Tesfay Mehari ◽  
Wubetu Gashaw ◽  
Kassa Tesfaye Dessale ◽  
...  

Background: Drug-therapy problems(DTPs) among hypertensive patients can result in patient’s morbidity and mortality. The main aim of this study was to assess drug therapy problem and associated factors among <="" span="" style="font-family: hypertensive patients.Methods: A hospital based cross sectional study was conducted. The data was collected from patients’ medical charts and through interview. Drug therapy problem was categorized according to Cipolle methods of DTP classification. Thedata was analyzed using the Statistical Package for the Social Sciences (SPSS), version 21.Results: A total of 241 patients were studied. The mean number of antihypertensive medications prescribed were 1.41±0.53. A total of 357 drug therapy problems(DTPs) were identified. From the patients studied,134(55.6%) had at least one evidence of drug therapy problem. Non adherence was the most commonly identified drug therapy problem occurred in (143(59.3%)) patients. Substance use (AOR=0.445, 95% CI= 0.227-0.870, p=0.018) and comorbidity (AOR= 2.099, 95% CI= 1.192-3.694, p=0.010) werethe predictors of DTP.Conclusion: More than half of the participants had evidence of onset drug therapy problem. Thus efforts that could boost antihypertensive compliance and minimizes substance use should be adopted to reduce patients’s drug therapy problems.Keywords: assessment, drug, therapy, problem, Ethiopia.

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Fahad M. Algabbani ◽  
Aljoharah M. Algabbani

Abstract Background Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of mortality globally. Patient’s adherence to treatment is a cornerstone factor in controlling hypertension and its complications. This study assesses hypertension patients’ adherence to treatment and its associated factors. Methods This cross-sectional study conducted in Riyadh, Saudi Arabia. The study targeted outpatients aged ≥18 years who were diagnosed with hypertension. Participants were recruited using a systemic sampling technique. The two main measurements were assessing adherence rate of antihypertensive medications using Morisky scale and identifying predictors of poor medication adherence among hypertensive patients including socio-economic and demographic data, health status, clinic visits, medication side effects, medications availability, and knowledge. Descriptive and logistic regression analyses were performed to assess factors associated with poor adherence. Results A total of 306 hypertensive outpatients participated in this study. 42.2% of participants were adherent to antihypertensive medications. Almost half of participants (49%) who reported having no comorbidities were adherent to antihypertensive medications compared to participants with one or more than one comorbidities 41, 39% respectively. The presence of comorbid conditions and being on multiple medications were significantly associated with medication adherence (P-values, respectively, < 0.004, < 0.009). Patients with good knowledge about the disease and its complications were seven times more likely to have good adherence to medication (P <  0.001). Conclusions Non-adherence to medications is prevalent among a proportion of hypertensive patients which urges continuous monitoring to medication adherence with special attention to at risks groups of patients. Patients with comorbidities and on multiple medications were at high risk of medication non-adherence. Patients’ knowledge on the disease was one of the main associated factors with non-adherence.


2021 ◽  
Vol Volume 14 ◽  
pp. 1681-1688
Author(s):  
Nigusie Selomon Tibebu ◽  
Tigabu Desie Emiru ◽  
Chalie Marew Tiruneh ◽  
Adane Birhau Nigat ◽  
Moges Wubneh Abate ◽  
...  

2020 ◽  
Author(s):  
Markos Desalegn Beyene ◽  
Robsan Gudeta Getachew ◽  
Workineh Diriba Gemechu

Abstract Background: Millions of people throughout the world are using substances such as alcohol, nicotine, cocaine, methamphetamine, morphine, marijuana, heroin and many others. Substance use by people in all parts of the world, particularly adolescents, has long been of scientific, political and public concern. Objective: -the main aim of this study was to prevalence of substance use & associated factors among Nekemte preparatory school students in 2019. Methodology:-. School based cross-sectional study was conducted among students at Nekemte preparatory school from March 20-30, 2018. Multistage stratified sampling method was employed to select 372 study participants. Collected data was cleaned and entered in to Epi info version 3.5.3 and transported to SPSS (statistical package for social sciences) version 20 for analysis. Descriptive statistics and logistic regression was done to indentify factors associated with substance use in the study area. Result: The overall prevalence of current substance use was (19.1%). Being male students [AOR, 95%CI; 4.64(2.18, 9.75)], ever encountered pressure from friends to use substances [AOR, 95% CI; 2.61(1.03, 6.63)], having substance user parents [AOR, 95%CI; 6.4(2.87, 14.30)] and having many substance user friends [AOR, 95%CI; 6.2(2.82, 13.75)] were significantly associated with substance use among students in the study area. Conclusion & Recommendation: The current prevalence of substance use among preparatory school students of this study area was low. The most commonly used substances were alcohol, khat and tobacco. Being male students, pear pressure, living with parents use substance & friends were found to affect substance use among Nekemte preparatory school students. Awareness creation sessions; Information, Education &Communication intervention should be intensified to further reduce Substance use among students.


Author(s):  
Gebreamlak Gidey ◽  
Desta Abraha

 Objective: The objective of this study was to assess the proportion and associated factors for early initiation of antenatal care visit in Mekelle City, Tigray, Northern Ethiopia, 2015.Method: An institution-based cross-sectional study was employed among 391 pregnant women’s in Mekelle special zone. A systematic sampling technique was used to select study participants. Pretested structured questionnaire was used to collect the data through interview. Data were entered into EPI info version 7 and analyzed using SPSS version 20, respectively. Bivariate and multivariate logistic regression was done to see significant variables with p<0.05 at 95% confidence interval (CI).Result: The proportion of pregnant women who initiate early antenatal care (ANC) visit was found to be 41.1%. Perceived correct time of initiation before 4 months (adjusted odds ratio [AOR]=3.261, 95% CI 1.391–7.645) and correct time told by others before 4 months with (AOR=6.617, 95% CI 2.580, 16.971) were found to have statistically significant positive outcomes association with early initiation of antenatal care visit.Conclusion: The proportion of early ANC initiation in Mekelle is lower than the World Health Organization recommendation which is <16 weeks gestation. Therefore, providing information to the community, initiation counseling, and providing health education on the benefits early ANC is crucial to improving maternal, neonatal, and child health outcomes.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Tolesa Fanta ◽  
Desalegn Bekele ◽  
Getinet Ayano

Abstract Background Depression is common among people with schizophrenia and associated with severe positive and negative symptoms, higher rates of disability, treatment resistance and mortality related to suicide, physical and drug-related causes. However, to our knowledge, no study has been conducted to report the magnitude of depression among people with schizophrenia in Ethiopia. Therefore, this study aimed to determine the prevalence and associated factors of depression among people with schizophrenia. Method A hospital-based cross-sectional study was conducted among 418 patients with schizophrenia selected by systematic sampling technique. Patient Health Questionnaire 9 (PHQ-9) was used to measure depression among the study participants. To identify the potential contributing factors, we performed binary and multivariable logistic regression analysis adjusting the model for the potential confounding factors. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI)) was determined to evaluate the strength of association. Result The prevalence estimate of depression among people with schizophrenia was found to be 18.0% [95% confidence interval: 14.50–22.30]. Our multivariable analysis revealed that current substance use (AOR 2.28, 95%CI (1.27, 4.09), suicide attempt (AOR 5.24, 95%CI (2.56, 10.72), duration of illness between 6 and 10 years (AOR 2.09, 95%CI (1.08, 4.04) and poor quality of life (AOR 3.13, 95%CI (1.79, 5.76) were found to be the factors associated with depression among people with schizophrenia. Conclusion The current study revealed that comorbid depression was high among people with schizophrenia and associated with current substance use, suicide attempt, and long duration of the illness as well as poor quality of life. Attention needs to be given to address comorbid depression among people with schizophrenia.


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