The pattern of head and neck malignant tumours in Jos.

2010 ◽  
Vol 8 (1) ◽  
Author(s):  
A.S Adoga ◽  
E.N John ◽  
S.J Yiltok ◽  
G.O Echejoh ◽  
O.G.B Nwaorgu
2017 ◽  
Vol 12 (3) ◽  
pp. 155-162 ◽  
Author(s):  
Raffaele Giusti ◽  
Paolo Bossi ◽  
Marco Mazzotta ◽  
Marco Filetti ◽  
Daniela Iacono ◽  
...  

Background: Head and neck (H&N) cancers account for about 5% of all malignant tumours. Pain is one of the most feared consequences of H&N neoplasms and is experienced by up to 80% of patients and worsens their quality of life inhibiting speaking, eating, drinking or swallowing. Nevertheless, pain is still often underestimated and undertreated. Objectives: The role of opioids in cancer pain has been well established but evidences about the role and the relative effectiveness of opioids such as fentanyl in the context of H&N cancer pain remains unclear. Methods: A literature review based on the guidance of the Centre for Reviews and Dissemination was conducted. An iterative approach was used starting with an electronic search in the MEDLINE database. The search terms ((‘Neoplasms’[Mesh]) AND ‘Head and Neck Neoplasms’[Mesh]) AND ‘Fentanyl’[Mesh] were used. Results: A total of 18 publications were found by the first performed search on PubMed. Other publications concordant with our aim were found by cross-reference. Considering inclusion and exclusion criteria for our review, eight papers resulted eligible for analysis. Conclusion: Fentanyl transdermal therapeutic system (TTS) seems to be an important option, thanks to the way of administration, the good safety and tolerability profiles to control baseline pain. For breakthrough cancer pain (BTcP), several formulations of transmucosal fentanyl are available. All the formulations seem to be active and safety but we lack head-to-head studies of fentanyl versus other strong opioids, as well as with different formulation of fentanyl, particularly for BTcP where H&N cancer population is very poorly represented.


1976 ◽  
Vol 4 (3) ◽  
pp. 158-164 ◽  
Author(s):  
Jaime G De-la-Garza ◽  
Francisco García Olivares ◽  
Carlos Armendariz ◽  
Angel-Mario Flores-F

Twenty cases originally diagnosed as epidermoid carcinoma were observed with a view to determining whether a combination of radiation and intravenous bleomycin promoted regression of the tumours and if so what effect this had on survival. Signs of local toxicity with this combination were also looked for. Five cases yielded what was considered to be an excellent response, nine cases gave a good response and six cases had a poor response. It is recommended that future studies be carried out in epidermoid carcinoma with this combination of radiotherapy and bleomycin.


1993 ◽  
Vol 107 (11) ◽  
pp. 1017-1020 ◽  
Author(s):  
Keitchi Ichimura ◽  
Toshlyoshi Tanaka

AbstractIn order to elucidate the causal mechanism of trismus in head and neck cancer, 21 patients manifesting trismus out of 212 patients with malignant tumours in the head and neck (treated in Tokyo University Branch Hospital from 1983 to 1991) were reviewed. Nine patients developed trismus either by infiltration of the muscles of mastication or by reflex spasm. Trismus was considered to have developed as a result of irradiation in five cases and of surgical intervention in seven cases. In some cases of oropharyngeal cancer, CT revealed no evidence of tumour invasion into the infratemporal fossa when trismus occurred, suggesting that trismus was caused either by the reflex spasm of muscles or by microinvasion too small to be seen in CT films. Maxillary sinus tumours were often without tnsmus even when they extended posteriorly to the infratemporal fossa.


2002 ◽  
Vol 116 (12) ◽  
pp. 1044-1046
Author(s):  
Annette H. C. Ang ◽  
Kenny Peter Pang ◽  
Luke K. S. Tan

Malignant tumours of the nasal cavities and paranasal sinuses are uncommon.They constitute less than one per cent of all tumours and less than three per cent of head and neck tumours. Although multiple primary carcinomas of the aerodigestive tract are commonly reported, metachronous maxillary sinus carcinomas are rare. To date, all of these cases reported are of squamous cell origin. The incidence of metachronous maxillary carcinoma involving both sinuses is in the range of 1.4 per cent amongst patients with maxillary carcinoma. We present the first reported case, to our knowledge, of a patient with metachronous adenocarcinoma of the maxillary sinus.


2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Usman Bello ◽  
Sanusi Muhammad Haruna ◽  
Ibrahim Hassan ◽  
Kabir Sulaiman ◽  
Kasimu Umar Adoke ◽  
...  

Background: Diseases of children in most developing countries revolve commonly around infectious disorders and malnutrition. However, other conditions including neoplastic diseases may be unassuming challenges to the attending physician. The objective of this study was to determine the epidemiological and histopathological pattern of malignant tumours among children in a northern Nigerian tertiary health institution. Materials and Methods: This is a retrospective study of malignant tumours in children aged fifteen years and below diagnosed over a ten year period (1st January 2011- 31st December 2020). Histopathology laboratory records at the Department of Pathology, Federal Medical Centre, Birnin Kebbi, Kebbi state, were reviewed and all diagnoses of malignant tumours were extracted. The findings were compared with similar studies elsewhere. Results: There were 36 children with confirmed cases of malignant tumours; 22 males and 14 females. The male to female ratio was 1.7:1. The peak age of incidence was 11-15years. The most common childhood malignant tumours were rhabdomyosarcoma, retinoblastoma, osteosarcoma, non-Hodgkin's lymphoma and squamous cell carcinoma. Head and neck region was the commonest area of affectation. Conclusion: The most common malignant tumours in children in our setting are sarcomas and small round blue cell tumours of childhood affecting predominantly older male children with head and neck regional predilections. Malignant tumours in children though not very common, are an important aspect of paediatric disorders to the attending physician due to their high morbidity and mortality. The diagnosis of such can be challenging to the pathologist, especially in resource constrain environments. High index of suspicion is therefore advocated to detect the tumour in its early stage that is associated with low morbidity and mortality.


Author(s):  
Udaya Kumar M. ◽  
Kranti Gouripur ◽  
S. Elangovan ◽  
V. Srinivasa

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Malignant neoplasms of the nose and paranasal sinuses are rare and account for 3% of malignancies involving head and neck region. Maxillary sinus is the commonest area affected and squamous cell carcinoma is the commonest malignancy reported. Due to nonspecific clinical features, late presentations and poor accessibility tumours in these areas are both therapeutically and diagnostically challenging. Data about maxillary sinus tumours, especially from Karaikal are lacking. This prospective hospital-based study was conducted to determine the common benign and malignant tumours affecting the maxilla, their epidemiology and to analyse their clinical presentations.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">Relevant epidemiological and clinical details were collected for all the patients with maxillary tumours and thorough clinical evaluation was performed. CT scan of head and neck region and histopathological examination of the lesion was carried out. All the details were tabulated and percentages were calculated for comparison and analysis.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">During two years period of the study 44 patients with tumours affecting the maxilla were detected, 32 (72%) being benign and 12 (27%) malignant. Incidence of both benign and malignant tumours was highest in the 51-60 years age group with male preponderance. Squamous cell carcinoma (58.33%) was the most common malignant histological variant found while inverted papilloma with squamous epithelium (62.5%) was the most common benign histological variant. In TNM staging, 42% patients had T4 and the remaining were T3 and T2. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">In Karaikal region, inverted papilloma with squamous epithelial lining and squamous cell carcinoma are the commonest benign and malignant tumours of maxilla respectively. Although clinical manifestations of both benign and malignant lesions overlap, certain features like facial pain, cheek swelling, loosening of teeth which were found only in association with carcinoma should warrant thorough evaluation.</span></p>


2007 ◽  
Vol 121 (7) ◽  
pp. 676-679 ◽  
Author(s):  
D Tamiolakis ◽  
E Proimos ◽  
G E Perogamvrakis ◽  
C E Skoulakis ◽  
G C Georgiou ◽  
...  

Background: Brushing cytology is a well established diagnostic procedure used by gynaecologists, physicians and surgeons to obtain representative samples from lesions. Our aim was to evaluate its reliability in ulcerative and tumour-like conditions arising in the skin of the head and neck.Methods: Over 28 months, 86 patients with suspected cutaneous malignant lesions underwent a cytological examination with a cytobrush within the otolaryngology department.Results: Cytological analysis identified 63 out of 64 histologically documented malignant tumours (60 primary basal cell and squamous cell carcinomas and three metastatic adenocarcinomas), and 21 out of 22 benign lesions. There was one false positive and one false negative result.Conclusions: Brushing cytology of suspected cutaneous malignant lesions is a rapid and reliable diagnostic method which helps the clinician to decide on appropriate planning and treatment. The technique can be performed as an out-patient procedure, and smear preparation can be done in the laboratory, even at a peripheral hospital.


2014 ◽  
Vol 19 (2) ◽  
pp. 175-177
Author(s):  
Junkichi Yokoyama ◽  
Masaki Yazawa ◽  
Hitoshi Yoshimoto ◽  
Keisuke Ueki ◽  
Shunsuke Kawamoto ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document