scholarly journals Effect of beet dietary fiber on lipid metabolism in rats fed a cholesterol-free diet in comparison with pectin and cellulose.

1989 ◽  
Vol 42 (4) ◽  
pp. 295-304 ◽  
Author(s):  
Tsutomu ARITSUKA ◽  
Katsusaburo TANAKA ◽  
Shuhachi KIRIYAMA
2021 ◽  
Vol 11 (4) ◽  
pp. 362-368
Author(s):  
Khayra Mebarek ◽  
Meryem Bensalah ◽  
Samira Bouanane ◽  
Fatima Zohra Baba Ahmed ◽  
Nesrine Samira Karaouzene ◽  
...  

Dietary fiber is a group of food components which is the subject of many studies on several aspects of human health. Recent research demonstrate that dietary fiber intake is associated with reduced diabetes risk. The aim of the present work was to test the effect of dietary fiber such as cellulose and mucilage on disorders of lipid metabolism induced by experimental diabetes in the aged Wistar rats. Diabetes was induced by intraperitoneal injection of streptozotocin. Aging male Wistar rats diabetic and control rats were fed highly-pure-cellulose-mucilage-enriched (HPCME) diet or control diet for 2 months. At the end of study, blood samples and tissue are collected for de-termination of biochemical parameters (glucose, total cholesterol, triglycer-ides and lipoproteins) and lipases activities. 2 months of HPCME diet intake by diabetic aged rats improves diabetic control, induced a decrease of body weight, a reduction of plasma lipid concentration, lower blood-glucose and a significant decrease in expression of pathway lipolytic enzyme activities va-lues witch decrease the prevalence of the specific disorders of diabetes. This study suggests that dietary fiber (HPCME), has an important physiological effect on glucose and lipid metabolism during aging which reduces the risk of developing complications of diabetes.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1654-1654
Author(s):  
Qian Li ◽  
Yuxiao Zou ◽  
Sentai Liao

Abstract Objectives In this study we compared the antiobesity effects of mulberry leaf powder, dietary fiber, polyphenols, and a fiber/polyphenols mixture.Combining intestinal community modulation and metabolite analysis, we investigated the antiobesity effects and mechanisms of mulberry leaf components, detecting the interaction between mulberry leaf dietary fiber and polyphenol. Methods An obesity model was established by feeding rats with a high-calorie diet. Rats were divided into seven groups: the obesity model control (MC), positive control (PC), mulberry leaf powder (MLP), mulberry leaf fiber (MLF), mulberry leaf polyphenols (MLPS), mulberry leaf fiber and polyphenols mixture (MLM), and normal control (NC), and fed daily for 6 consecutive weeks.the 16S rRNA gene was sequenced using Illumina MiSeq.UPLC Triple TOF MS/MS system and Agilent 6890 N GC-MS were used to profile the urinary/fecal metabolites. Results The synergistic interaction between mulberry dietary fiber and polyphenols (MLM) in antiobesity was reported for the first time. The content of Firmicutes in the MC group was increased significantly. Except for the MLPS group, other test groups regulated the Firmicutes content to a normal level. Our study demonstrated that different components of mulberry leaves might achieve weight loss by reducing the amount of Lachnespiraceae. At the same time, the reduction Lactobacillus_vaginalis and Lactobacillus_gasseri species was closely related to the improvement of lipid metabolism profiles. In addition, the high energy diet induced feces and urine metabolic disorders in MC group with significant difference. The amino acid and oligopeptide metabolites were regulated to the NC level under the regulation of mulberry leaf components. Conclusions MLM group had the best efficiency on weight loss, indicating synergistic interactions between MLPS and MLF. The reduction of Firmicutes abundance, and the downstream Clostridiales, Lachnespiraceae, was a key pathway for the antiobesity effects. The increased abundances of Lactobacillus vaginalis and Lactobacillus gasseri might result in lipid metabolism disorder. The test groups regulated the amino acid and oligopeptides metabolic disorder tents to normal levels compared with the MC and NC groups. Funding Sources The Science & Technology Projects of Guangdong Province No.2017A050501022/No.2017A030310416.


1991 ◽  
Vol 65 (9) ◽  
pp. 1337-1342
Author(s):  
Tsutomu ARITSUKA ◽  
Hidetoshi TAKEDA ◽  
Shuhachi KIRIYAMA

2021 ◽  
Vol 24 (2) ◽  
pp. 124-134
Author(s):  
Jia Han ◽  
Rui Zhang ◽  
Dina Muheyati ◽  
Mei Xia Lv ◽  
Wubulikasimu Aikebaier ◽  
...  

2003 ◽  
Vol 4 (2) ◽  
pp. 278 ◽  
Author(s):  
S.H. Lee ◽  
H.J. Park ◽  
H.K. Chun ◽  
S.Y. Cho ◽  
H.G. Hwang ◽  
...  

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