scholarly journals Recovery Off-Kinetics Following Exhaustive Upper Body Exercise in Spinal Cord Injury

2020 ◽  
Vol 26 (4) ◽  
pp. 304-313
Author(s):  
Donal Murray ◽  
Lisa M.K. Chin ◽  
Rachel E. Cowan ◽  
Suzanne L. Groah ◽  
Randall E. Keyser
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Vigorous Physical Activity ◽  
Exponential Model ◽  
Cardiopulmonary Exercise Test ◽  
Lactate Clearance ◽  
Upper Body ◽  
Control Group ◽  
Upper Body Exercise ◽  
Cord Injury

Background: People with spinal cord injury (SCI) present with impaired autonomic control when the lesion is above T6. This could lead to delayed cardiorespiratory recovery following vigorous physical activity. Objectives: To characterize and compare gas exchange off-kinetics following exhaustive exercise in individuals with SCI and an apparently healthy control group. Methods: Participants were 19 individuals with SCI who presented with the inability to voluntarily lift their legs against gravity (age, 44.6 ± 14.2 years; AIS A, n = 5; AIS B, n = 7; AIS C, n = 7; paraplegia, n = 14; tetraplegia, n = 5) and 10 healthy comparisons (COM; age, 30.5 ± 5.3 years). All participants performed an arm ergometer cardiopulmonary exercise test (aCPET) to volitional exhaustion followed by a 10-minute passive recovery. O2 uptake (V̇o2) and CO2 output (V̇co2) off-kinetics was examined using a mono-exponential model in which tau off (τoff) and mean response time (MRT) were determined. The off-kinetics transition constant (Ktoff) was calculated as ΔV̇o2/MRT. Student t tests were used to compare SCI versus COM group means. Results: COM had a significantly higher relative peak V̇o2 compared to SCI (1.70 ± 0.55 L/min vs 1.19 ± 0.51 L/min, p = .019). No difference was observed for τoff between the groups, however Ktoff for both V̇o2 and V̇co2 was significantly lower in the SCI compared to the COM group. Conclusion: A reduced Ktoff during recovery may suggest inefficiencies in replenishing muscle ATP stores and lactate clearance in these participants with SCI. These findings may contribute to the observed lower cardiorespiratory fitness and greater fatigability typically reported in individuals with SCI.

Seated Double-Poling Ergometer Performance of Individuals with Spinal Cord Injury – A New Ergometer Concept for Standardized Upper Body Exercise

2012 ◽  
Vol 34 (02) ◽  
pp. 176-182
Author(s):  
A. Bjerkefors ◽  
F. Tinmark ◽  
J. Nilsson ◽  
A. Arndt
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Upper Body ◽  
Upper Body Exercise ◽  
Cord Injury ◽  
Double Poling

Upper-Body Exercise Improves Indices of Physical and Psychological Functioning in Persons With Spinal Cord Injury

2017 ◽  
Vol 98 (10) ◽  
pp. e18
Author(s):  
James Bilzon ◽  
Peter Rouse ◽  
Jean-Philippe Walhin ◽  
Dylan Thompson ◽  
Tom Nightingale
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Psychological Functioning ◽  
Upper Body ◽  
Upper Body Exercise ◽  
Cord Injury

ANALYSES OF TONE IN SPINAL CORD INJURY PATIENTS WITH SPASTIC PARAPLEGIA FOLLOWING STANDING AND UPPER BODY EXERCISE

1997 ◽  
Vol 14 (4) ◽  
pp. 345
Author(s):  
Morris A. Fisher ◽  
Linda Fehr ◽  
Edwin W. Langbein ◽  
Patricia Sibley
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Upper Body ◽  
Spastic Paraplegia ◽  
Upper Body Exercise ◽  
Cord Injury

Increasing Physical Activity in Spinal Cord Injury: Upper-Body Exercise Alone Not Enough?

2016 ◽  
Vol 97 (1) ◽  
pp. 171
Author(s):  
Daniel P. Credeur ◽  
Lee Stoner ◽  
David R. Dolbow
Keyword(s):  
Physical Activity ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Upper Body ◽  
Upper Body Exercise ◽  
Cord Injury

scholarly journals Exercise-induced diaphragm fatigue in a Paralympic champion rower with spinal cord injury

2018 ◽  
Vol 124 (3) ◽  
pp. 805-811 ◽  
Author(s):  
Nicholas B. Tiller ◽  
Thomas R. Aggar ◽  
Christopher R. West ◽  
Lee M. Romer
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Pulmonary Ventilation ◽  
Time Trial ◽  
Upper Body ◽  
Upper Body Exercise ◽  
Transdiaphragmatic Pressure ◽  
Cord Injury ◽  
Exercise Induced ◽  
Diaphragm Fatigue

The aim of this case report was to determine whether maximal upper body exercise was sufficient to induce diaphragm fatigue in a Paralympic champion adaptive rower with low-lesion spinal cord injury (SCI). An elite arms-only oarsman (age: 28 yr; stature: 1.89 m; and mass: 90.4 kg) with motor-complete SCI (T12) performed a 1,000-m time trial on an adapted rowing ergometer. Exercise measurements comprised pulmonary ventilation and gas exchange, diaphragm EMG-derived indexes of neural respiratory drive, and intrathoracic pressure-derived indexes of respiratory mechanics. Diaphragm fatigue was assessed by measuring pre- to postexercise changes in the twitch transdiaphragmatic pressure (Pdi,tw) response to anterolateral magnetic stimulation of the phrenic nerves. The time trial (248 ± 25 W, 3.9 min) elicited a peak O2 uptake of 3.46 l/min and a peak pulmonary ventilation of 150 l/min (57% MVV). Breath-to-stroke ratio was 1:1 during the initial 400 m and 2:1 thereafter. The ratio of inspiratory transdiaphragmatic pressure to diaphragm EMG (neuromuscular efficiency) fell from rest to 600 m (16.0 vs. 3.0). Potentiated Pdi,tw was substantially reduced (−33%) at 15–20 min postexercise, with only partial recovery (−12%) at 30–35 min. This is the first report of exercise-induced diaphragm fatigue in SCI. The decrease in diaphragm neuromuscular efficiency during exercise suggests that the fatigue was partly due to factors independent of ventilation (e.g., posture and locomotion). NEW & NOTEWORTHY This case report provides the first objective evidence of exercise-induced diaphragm fatigue in spinal cord injury (SCI) and, for that matter, in any population undertaking upper body exercise. Our data support the notion that high levels of exercise hyperpnea and factors other than ventilation (e.g., posture and locomotion) are responsible for the fatigue noted after upper body exercise. The findings extend our understanding of the limits of physiological function in SCI.

scholarly journals The effects of upper body exercise on the physical capacity of people with a spinal cord injury: a systematic review

2007 ◽  
Vol 21 (4) ◽  
pp. 315-330 ◽  
Author(s):  
Linda Valent ◽  
Annet Dallmeijer ◽  
Han Houdijk ◽  
Eelkje Talsma ◽  
Luc van der Woude
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Physical Capacity ◽  
Upper Body ◽  
Upper Body Exercise ◽  
Cord Injury

VO2 Off-Kinetics Following Exhaustive Upper Body Exercise Test in Spinal Cord Injury

2017 ◽  
Vol 49 (5S) ◽  
pp. 629-630
Author(s):  
Donal Murray ◽  
Rachel E. Cowan ◽  
Suzanne L. Groah ◽  
Inger H. Liungberg ◽  
Amanda K. Rounds ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Exercise Test ◽  
Upper Body ◽  
Upper Body Exercise ◽  
Cord Injury

scholarly journals Exercise Ameliorates Spinal Cord Injury by Changing DNA Methylation

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 143
Author(s):  
Ganchimeg Davaa ◽  
Jin Young Hong ◽  
Tae Uk Kim ◽  
Seong Jae Lee ◽  
Seo Young Kim ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Motor Cortex ◽  
Functional Recovery ◽  
Treadmill Exercise ◽  
Exercise Group ◽  
Control Group ◽  
Epigenetic Changes ◽  
Cord Injury ◽  
The Brain

Exercise training is a traditional method to maximize remaining function in patients with spinal cord injury (SCI), but the exact mechanism by which exercise promotes recovery after SCI has not been identified; whether exercise truly has a beneficial effect on SCI also remains unclear. Previously, we showed that epigenetic changes in the brain motor cortex occur after SCI and that a treatment leading to epigenetic modulation effectively promotes functional recovery after SCI. We aimed to determine how exercise induces functional improvement in rats subjected to SCI and whether epigenetic changes are engaged in the effects of exercise. A spinal cord contusion model was established in rats, which were then subjected to treadmill exercise for 12 weeks. We found that the size of the lesion cavity and the number of macrophages were decreased more in the exercise group than in the control group after 12 weeks of injury. Immunofluorescence and DNA dot blot analysis revealed that levels of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) in the brain motor cortex were increased after exercise. Accordingly, the expression of ten-eleven translocation (Tet) family members (Tet1, Tet2, and Tet3) in the brain motor cortex also elevated. However, no macrophage polarization was induced by exercise. Locomotor function, including Basso, Beattie, and Bresnahan (BBB) and ladder scores, also improved in the exercise group compared to the control group. We concluded that treadmill exercise facilitates functional recovery in rats with SCI, and mechanistically epigenetic changes in the brain motor cortex may contribute to exercise-induced improvements.

Sign in / Sign up

Export Citation Format

Share Document