scholarly journals Cost-effectiveness of algorithms

2015 ◽  
Vol Vol. 17 no. 1 (Discrete Algorithms) ◽  
Author(s):  
Graham Farr
Keyword(s):  
Cost Effectiveness ◽  
Input Sequence ◽  
Cost Effective ◽  
Maximum Matching ◽  
Graph Colouring ◽  
Solution Quality ◽  
Worst Case ◽  
Average Case ◽  
Time Investment ◽  
Bounded Complexity

Discrete Algorithms International audience In this paper we discuss how to assess the performance of algorithms for optimisation problems in a way that balances solution quality and time. We propose measures of cost-effectiveness for such algorithms. These measures give the gain in solution quality per time unit over a sequence of inputs, and give a basis for deciding which algorithm to use when aiming for best accumulated solution quality for a given time investment over such an input sequence. Cost-effectiveness measures can be defined for both average-case and worst-case performance. We apply these ideas to three problems: maximum matching, graph colouring and Kolmogorov complexity. For the latter, we propose a cost-effectiveness measure for the time-bounded complexity Kτ(x), and argue that it can be used to measure the cost-effectiveness both of finding a short program to output x and of generating x from such a program. Under mild assumptions, we show that (roughly speaking) if the time-bounded complexity Kτ(x) is to be a cost-effective approximation to K(x) then τ(n)=O(n2).

scholarly journals Strategyproof auction mechanisms for network procurement

OR Spectrum ◽  
2020 ◽  
Vol 42 (4) ◽  
pp. 965-994
Author(s):  
Martin Bichler ◽  
Zhen Hao ◽  
Richard Littmann ◽  
Stefan Waldherr
Keyword(s):  
Heuristic Algorithms ◽  
Allocative Efficiency ◽  
Telecommunications Industry ◽  
Steiner Tree Problem ◽  
Solution Quality ◽  
Worst Case ◽  
Average Case ◽  
Auction Mechanisms ◽  
Deferred Acceptance ◽  
Minimum Steiner Tree Problem

Abstract Deferred-acceptance auctions can be seen as heuristic algorithms to solve $${{\mathcal {N}}}{{\mathcal {P}}}$$ N P -hard allocation problems. Such auctions have been used in the context of the Incentive Auction by the US Federal Communications Commission in 2017, and they have remarkable incentive properties. Besides being strategyproof, they also prevent collusion among participants. Unfortunately, the worst-case approximation ratio of these algorithms is very low in general, but it was observed that they lead to near-optimal solutions in experiments on the specific allocation problem of the Incentive Auction. In this work, which is inspired by the telecommunications industry, we focus on a strategic version of the minimum Steiner tree problem, where the edges are owned by bidders with private costs. We design several deferred-acceptance auctions (DAAs) and compare their performance to the Vickrey–Clarke–Groves (VCG) mechanism as well as several other approximation mechanisms. We observe that, even for medium-sized inputs, the VCG mechanisms experiences impractical runtimes and that the DAAs match the approximation ratios of even the best strategy-proof mechanisms in the average case. We thus provide another example of an important practical mechanism design problem, where empirics suggest that carefully designed deferred-acceptance auctions with their superior incentive properties need not come at a cost in terms of allocative efficiency. Our experiments provide insights into the trade-off between solution quality and runtime and into the additional premium to be paid in DAAs to gain weak group-strategyproofness rather than just strategyproofness.

scholarly journals Intravascular Ultrasound Versus Angiography-Guided Drug-Eluting Stent Implantation: A Health Economic Analysis

2021 ◽  
Vol 14 (5) ◽  
Author(s):  
Jennifer Zhou ◽  
Danny Liew ◽  
Stephen J. Duffy ◽  
James Shaw ◽  
Antony Walton ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Intravascular Ultrasound ◽  
Stent Implantation ◽  
Cost Effective ◽  
Drug Eluting Stent ◽  
Worst Case ◽  
System Perspective ◽  
Life Years ◽  
Drug Eluting ◽  
The Cost

Background: There is increasing evidence that use of intravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) is associated with improved clinical outcomes compared with angiography guidance alone. However, concern regarding the cost-effectiveness of IVUS has limited use of this technology worldwide. In this study, we aimed to evaluate the cost-effectiveness of IVUS-guided PCI compared with angiography-guided PCI in patients undergoing drug-eluting stent implantation. Methods: A decision-analytic Markov model was constructed to compare the cost-effectiveness of IVUS to angiography guidance from the Australian healthcare system perspective. Procedure-related morbidity and mortality were estimated from the literature. Costs were obtained from Australian sources. The population of interest was all-comers undergoing PCI with drug-eluting stent. Outcomes of interest included costs, life-expectancy, and quality-adjusted life years (QALYs) for both treatment groups. Results: In the base case, IVUS guidance was cost-effective compared with angiography guidance alone. With 5% annual discounting, IVUS was associated with increased lifetime costs of Australian dollars (AUD) $823 (USD $597) per person and benefits of 0.04 life years and 0.05 QALYs compared with angiography, yielding an incremental cost-effectiveness ratio of AUD $17 539 (USD $12 730) per QALY gained. Results were robust to sensitivity analyses, with IVUS being cost-effective in 99% of 10 000 Monte Carlo iterations assuming a willingness-to-pay threshold of AUD $50 000 per QALY gained. In a worst-case scenario analysis, IVUS remained the cost-effective option, with an ICER of AUD $36 651 (USD $26 601) per QALY gained. Exploratory subgroup analysis revealed that cost-effectiveness may be greatest among patients with left main and complex coronary lesions. Conclusions: Use of IVUS guidance during PCI is likely to be cost-effective compared with angiography guidance alone among patients undergoing drug-eluting stent implantation.

scholarly journals An Average Case NP-complete Graph Colouring Problem

2018 ◽  
Vol 27 (5) ◽  
pp. 808-828 ◽  
Author(s):  
LEONID A. LEVIN ◽  
RAMARATHNAM VENKATESAN
Keyword(s):  
Random Graphs ◽  
Polynomial Time ◽  
Complete Graph ◽  
Graph Colouring ◽  
Worst Case ◽  
Average Case ◽  
Graph Problem ◽  
Complete Problems ◽  
Np Complete ◽  
Np Problems

NP-complete problems should be hard on some instances but those may be extremely rare. On generic instances many such problems, especially related to random graphs, have been proved to be easy. We show the intractability of random instances of a graph colouring problem: this graph problem is hard on average unless all NP problems under all samplable (i.e. generatable in polynomial time) distributions are easy. Worst case reductions use special gadgets and typically map instances into a negligible fraction of possible outputs. Ours must output nearly random graphs and avoid any super-polynomial distortion of probabilities. This poses significant technical difficulties.

scholarly journals Rotational thromboelastometry in the perioperative period of cardiac surgeries: cost-effectiveness analysis and budget impact

2020 ◽  
Vol 12 (3) ◽  
pp. 173-188
Author(s):  
André Soares Santos ◽  
◽  
Ananda Jessyla Felix Oliveira ◽  
Magda Lourenço Fernandes ◽  
José Luiz dos Santos Nogueira ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Impact Analysis ◽  
Budget Impact ◽  
Cost Effective ◽  
Perioperative Period ◽  
Base Case ◽  
Case Scenario ◽  
Base Case Scenario ◽  
Worst Case ◽  
Worst Case Scenario

Objective: The transfusion of blood components and blood products in cardiac surgery patients can be guided by protocols based on standard laboratory tests and/or clinical decisions (Standardof-Care, SOC) or viscoelastic haemostatic assays (VHA). The aim of this study is to evaluate the cost-effectiveness and budget impact of VHAs compared to SOC. Methods: A decision tree model was built in TreeAge Pro® 2009. Costs and benefits were taken from the medical literature. The costeffectiveness was evaluated in a base-case scenario and a worst-case scenario, considering low costs of adverse events. The budget impact was evaluated from data taken from Datasus. Cost data were measured in 2019 USD and outcomes were measured in QALYs. Results: VHAs were considered dominant in the base-case scenario and very cost-effective in the worst-case scenario (ICER = $1,083.21 USD/QALY). The budget impact analysis varied from a cost-saving result in the base-case scenario to a reasonable increase in cost in the worst-case scenario. Since the total market share of the technology is unlikely, a reasonable estimative for the base-case scenario and the worst-case scenario are about -$275 million USD and $132 million USD, respectively. Conclusion: We conclude that the VHAs are cost-effective and should be recommended for the use in the perioperative period of cardiac surgeries, especially for patients with a high risk of hemorrhage or coagulation problems.

Within trial cost-effectiveness of a structured lifestyle intervention in adults with overweight/obesity and type 2 diabetes: Results from the Action for Health in Diabetes (Look AHEAD) Study

2020 ◽  
Author(s):  
Ping Zhang ◽  
Karen M. Atkinson ◽  
George Bray ◽  
Haiying Chen ◽  
Jeanne M. Clark ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cost Effectiveness ◽  
Lifestyle Intervention ◽  
Health Utility Index ◽  
Health Benefit ◽  
Cost Effective ◽  
Health Utility ◽  
Health Care Expenditures ◽  
Quality Adjusted Life Year

<b>OBJECTIVE </b>To assess the cost-effectiveness (CE) of an intensive lifestyle intervention (ILI) compared to standard diabetes support and education (DSE) in adults with overweight/obesity and type 2 diabetes, as implemented in the Action for Health in Diabetes study. <p><b>RESEARCH DESIGN AND METHODS</b> Data were from 4,827 participants during the first 9 years of the study from 2001 to 2012. Information on Health Utility Index-2 and -3, SF-6D, and Feeling Thermometer [FT]), cost of delivering the interventions, and health expenditures were collected during the study. CE was measured by incremental cost-effectiveness ratios (ICERs) in costs per quality-adjusted life year (QALY). Future costs and QALYs were discounted at 3% annually. Costs were in 2012 US dollars. </p> <p><b>RESULTS </b><a>Over the </a>9 years studied, the mean cumulative intervention costs and mean cumulative health care expenditures were $11,275 and $64,453 per person for ILI and $887 and $68,174 for DSE. Thus, ILI cost $6,666 more per person than DSE. Additional QALYs gained by ILI were not statistically significant measured by the HUIs and were 0.17 and 0.16, respectively, measured by SF-6D and FT. The ICERs ranged from no health benefit with a higher cost based on HUIs, to $96,458/QALY and $43,169/QALY, respectively, based on SF-6D and FT. </p> <p><b>Conclusions </b>Whether<b> </b>ILI was cost-effective over the 9-year period is unclear because different health utility measures led to different conclusions. </p>

Rule Based Classifiers for Suspect Detection from CCTV Footages

2020 ◽  
Vol 13 ◽  
Author(s):  
Sunil Pathak
Keyword(s):  
Answer Sheet ◽  
Normal Activity ◽  
Contact Detection ◽  
Accuracy Rate ◽  
Hand Detection ◽  
Worst Case ◽  
Average Case ◽  
The Face ◽  
Case Simulation ◽  
Material Exchange

Background: The significant work has been present to identify suspects, gathering information and examining any videos from CCTV Footage. This exploration work expects to recognize suspicious exercises, i.e. object trade, passage of another individual, peeping into other's answer sheet and individual trade from the video caught by a reconnaissance camera amid examinations. This requires the procedure of face acknowledgment, hand acknowledgment and distinguishing the contact between the face and hands of a similar individual and that among various people. Methods: Segmented frames has given as input to obtain foreground image with the help of Gaussian filtering and background modeling method. Suh foreground images has given to Activity Recognition model to detect normal activity or suspicious activity. Results: Accuracy rate, Precision and Recall are calculate for activities detection, contact detection for Best Case, Average Case and Worst Case. Simulation results are compare with performance parameter such as Material Exchange, Position Exchange, and Introduction of a new person, Face and Hand Detection and Multi Person Scenario. Conclusion: In this paper, a framework is prepared for suspect detection. This framework will absolutely realize an unrest in the field of security observation in the training area.

scholarly journals Cost-Effectiveness Analysis of BCG Vaccination against Tuberculosis in Indonesia: A Model-Based Study

Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 707
Author(s):  
Afifah Machlaurin ◽  
Franklin Christiaan Karel Dolk ◽  
Didik Setiawan ◽  
Tjipke Sytse van der Werf ◽  
Maarten J. Postma
Keyword(s):  
Cost Effectiveness ◽  
Univariate Analysis ◽  
Cost Effective ◽  
Epidemiological Data ◽  
Control Programme ◽  
Detection Rates ◽  
Middle Income ◽  
Bcg Vaccination ◽  
Life Years ◽  
The Cost

Bacillus Calmette–Guerin (BCG), the only available vaccine for tuberculosis (TB), has been applied for decades. The Indonesian government recently introduced a national TB disease control programme that includes several action plans, notably enhanced vaccination coverage, which can be strengthened through underpinning its favourable cost-effectiveness. We designed a Markov model to assess the cost-effectiveness of Indonesia’s current BCG vaccination programme. Incremental cost-effectiveness ratios (ICERs) were evaluated from the perspectives of both society and healthcare. The robustness of the analysis was confirmed through univariate and probabilistic sensitivity analysis (PSA). Using epidemiological data compiled for Indonesia, BCG vaccination at a price US$14 was estimated to be a cost-effective strategy in controlling TB disease. From societal and healthcare perspectives, ICERs were US$104 and US$112 per quality-adjusted life years (QALYs), respectively. The results were robust for variations of most variables in the univariate analysis. Notably, the vaccine’s effectiveness regarding disease protection, vaccination costs, and case detection rates were key drivers for cost-effectiveness. The PSA results indicated that vaccination was cost-effective even at US$175 threshold in 95% of cases, approximating the monthly GDP per capita. Our findings suggest that this strategy was highly cost-effective and merits prioritization and extension within the national TB programme. Our results may be relevant for other high endemic low- and middle-income countries.

scholarly journals Cost Effectiveness of Transbronchial Needle Aspiration

1999 ◽  
Vol 6 (4) ◽  
pp. 332-335 ◽  
Author(s):  
Jennifer A Crocket ◽  
Eric YL Wong ◽  
Dale C Lien ◽  
Khanh Gia Nguyen ◽  
Michelle R Chaput ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Cost Effective ◽  
Diagnostic Procedures ◽  
Needle Aspiration ◽  
Benign Disease ◽  
University Hospital ◽  
High Yield ◽  
Transbronchial Needle Aspiration ◽  
Computed Tomographic ◽  
The Cost

OBJECTIVE: To evaluate the yield and cost effectiveness of transbronchial needle aspiration (TBNA) in the assessment of mediastinal and/or hilar lymphadenopathy.DESIGN: Retrospective study.SETTING: A university hospital.POPULATION STUDIED: Ninety-six patients referred for bronchoscopy with computed tomographic evidence of significant mediastinal or hilar adenopathy.RESULTS: Ninety-nine patient records were reviewed. Three patients had two separate bronchoscopy procedures. TBNA was positive in 42 patients (44%) and negative in 54 patients. Of the 42 patients with a positive aspirate, 40 had malignant cytology and two had cells consistent with benign disease. The positive TBNA result altered management in 22 of 40 patients with malignant disease and one of two patients with benign disease, thereby avoiding further diagnostic procedures. The cost of these subsequent procedures was estimated at $27,335. No complications related to TBNA were documented.CONCLUSIONS: TBNA is a high-yield, safe and cost effective procedure for the diagnosis and staging of bronchogenic cancer.

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