scholarly journals Q Fever in the Differential Diagnosis of COVID 19 Infection

2021 ◽  
Author(s):  
Sevil ALKAN ◽  
Alper ŞENER ◽  
Safiye Bilge GÜÇLÜ KAYTA ◽  
Anıl AKÇA
Keyword(s):  
Differential Diagnosis ◽  
Q Fever

scholarly journals Com1 as a Promising Protein for the Differential Diagnosis of the Two Forms of Q Fever

Pathogens ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 242 ◽  
Author(s):  
Vranakis ◽  
Mathioudaki ◽  
Kokkini ◽  
Psaroulaki
Keyword(s):  
Differential Diagnosis ◽  
Phase I ◽  
Clinical Diagnosis ◽  
Q Fever ◽  
Control Group ◽  
Virulence Potential ◽  
Chronic Q Fever ◽  
Candidate Protein ◽  
Immunogenic Proteins ◽  
Human Infections

Coxiella burnetii is the causative agent of acute and chronic Q fever in humans. Although the isolates studied so far showed a difference in virulence potential between those causing the two forms of the disease, implying a difference in their proteomic profile, the methods used so far to diagnose the two forms of the disease do not provide sufficient discriminatory capability, and human infections may be often misdiagnosed. The aim of the current study was to identify the outer membrane Com1 (CBU_1910) as a candidate protein for serodiagnostics of Q fever. The protein was cloned, expressed, purified, and used as an antigen in ELISA. The protein was then used for the screening of sera from patients suffering from chronic Q fever endocarditis, patients whose samples were negative for phase I immunoglobulin G (IgG), patients for whom at least one sample was positive for phase I IgG, and patients suffering from any kind of rheumatoid disease. Blood donors were used as the control group. Following statistical analysis, 92.4% (122/132) of the samples tested agreed with the negative clinical diagnosis, and 72.2% (26/36) agreed with the positive clinical diagnosis. Moreover, a significant correlation to the presence of the disease (p = 0.00) was calculated. The results support the idea that a Com1 antigen-based serodiagnostic test may be useful for differential diagnosis of chronic Q fever. Further studies are required to compare more immunogenic proteins of the bacterium against samples originating from patients suffering from different forms of the disease.

A pilot program for clinical Q fever surveillance as a first step for a standardized differential diagnosis of abortions: Organizational lessons applied to goats farms

2018 ◽  
Vol 163 ◽  
pp. 60-64
Author(s):  
Renée de Cremoux ◽  
Kristel Gache ◽  
Elodie Rousset ◽  
Carole Sala ◽  
Soline Hosteing ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Q Fever ◽  
Pilot Program

scholarly journals Granulomatous hepatitis caused by Q fever: a differential diagnosis of fever of unknown origin

2013 ◽  
Vol 12 (1) ◽  
pp. 138-141 ◽  
Author(s):  
Nancy Aguilar-Olivos ◽  
María del Carmen Manzano-Robleda ◽  
Ylse Gutiérrez-Grobe ◽  
Fredy Chablé-Montero ◽  
Jorge Albores-Saavedra ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Fever Of Unknown Origin ◽  
Q Fever ◽  
Unknown Origin ◽  
Granulomatous Hepatitis

Q fever presenting as miliary pneumonia: Case imagery and differential diagnosis

2019 ◽  
Vol 3 (3) ◽  
pp. 164-165
Author(s):  
Simon Couillard ◽  
Maryse Bélanger ◽  
Nicole Bouchard
Keyword(s):  
Differential Diagnosis ◽  
Q Fever ◽  
Pneumonia Case

scholarly journals Modern aspects of differential diagnosis of the Crimean-Congo hemorrhagic fever

2014 ◽  
Vol 95 (5) ◽  
pp. 748-751
Author(s):  
L P Cherenova ◽  
H M Galimzyanov ◽  
V V Vasilkova ◽  
I V Cherenov
Keyword(s):  
Differential Diagnosis ◽  
Clinical Symptoms ◽  
Q Fever ◽  
Laboratory Data ◽  
Hemorrhagic Fever ◽  
Epidemiological Data ◽  
Diagnostic Features ◽  
Crimean Congo Hemorrhagic Fever ◽  
Abdominal Bleeding ◽  
Pathogenetic Therapy

Aim. To lay down criteria for the differential diagnosis of Crimean-Congo hemorrhagic fever with a number of natural focal diseases prevalent in the Astrakhan region. Methods. A retrospective analysis of clinical, epidemiological and laboratory data of patients with Crimean-Congo hemorrhagic fever (74 cases), Astrakhan rickettsial fever (75), Q fever (75) and leptospirosis (25) was carried out in 2000-2013. Results. The basic clinical symptoms characteristic of the Crimean-Congo hemorrhagic fever for the differential diagnosis of Astrakhan rickettsial fever, Q fever and leptospirosis were distinguished. The early diagnosis of Crimean-Congo hemorrhagic fever was based on the epidemiological data taking into account spring-summer seasonality of the disease, patient’s visits to countryside, contact with animals, and data about tick bites and contact with ticks. Timely prescription of adequate antiviral and pathogenetic therapy helped to reduce the rate of severe forms and mortality from Crimean-Congo hemorrhagic fever. Conclusion. Differential diagnostic features of Crimean-Congo hemorrhagic fever were: the presence of the primary affect on the site of the tick bite, high body temperature, two-wave fever, significant signs of intoxication, the relative and absolute bradycardia, hemorrhagic rash, abdominal bleeding, changes of peripheral blood - leukopenia and thrombocytopenia.

Tumor Diagnosis

1982 ◽  
Vol 40 ◽  
pp. 262-265
Author(s):  
Bruce Mackay
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Differential Diagnosis ◽  
Light Microscopy ◽  
Clinical Examination ◽  
Ultrastructural Study ◽  
Diagnostic Procedures ◽  
Specific Diagnosis ◽  
Transmission Electron ◽  
Microscopic Diagnosis

The broadest application of transmission electron microscopy (EM) in diagnostic medicine is the identification of tumors that cannot be classified by routine light microscopy. EM is useful in the evaluation of approximately 10% of human neoplasms, but the extent of its contribution varies considerably. It may provide a specific diagnosis that can not be reached by other means, but in contrast, the information obtained from ultrastructural study of some 10% of tumors does not significantly add to that available from light microscopy. Most cases fall somewhere between these two extremes: EM may correct a light microscopic diagnosis, or serve to narrow a differential diagnosis by excluding some of the possibilities considered by light microscopy. It is particularly important to correlate the EM findings with data from light microscopy, clinical examination, and other diagnostic procedures.

The Preschool Stuttering Screen for Health Care Professionals

2011 ◽  
Vol 21 (2) ◽  
pp. 59-62
Author(s):  
Joseph Donaher ◽  
Christina Deery ◽  
Sarah Vogel
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Differential Diagnosis ◽  
Preschool Children ◽  
Health Care Professionals ◽  
Healthcare Professionals ◽  
Evidence Based ◽  
Developmental Profile

Healthcare professionals require a thorough understanding of stuttering since they frequently play an important role in the identification and differential diagnosis of stuttering for preschool children. This paper introduces The Preschool Stuttering Screen for Healthcare Professionals (PSSHP) which highlights risk factors identified in the literature as being associated with persistent stuttering. By integrating the results of the checklist with a child’s developmental profile, healthcare professionals can make better-informed, evidence-based decisions for their patients.

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