scholarly journals A NOBEL APPROACH OF DIABETIC NEUROPATHY & ITS MANAGEMENT THROUGH AYURVEDA

2021 ◽  
Vol p5 (5) ◽  
pp. 3012-3021
Author(s):  
Rahul Parihar ◽  
Pratyush Sharma ◽  
Pandey A. K.

Diabetes mellitus vis a vis Madhumeha is a multi-factorial metabolic disorder of the 21st century. It is caused by an absolute or a relative lack of insulin. Its manifestations include hyperglycemia, other metabolic derangements, and long-term damage to blood vessels, eyes, nerves, kidneys, and the heart. It is a leading cause of cardiac death, nonfatal MI, heart failure and stroke. It is also the most common cause of adult blindness, end-stage renal disease, non-traumatic leg amputation and neuropathy. Diabetes mellitus is one of the oldest diseases recognized since antiquity. It is amazing that 7 century B.C. Ayurvedic texts like Charaka and Sushruta Samhita have been described high caloric diet and sedentary habits as an important causative factor of Apathyanitmittaja Prameha and genetic/hereditary factors described as Sahaja Prameha. Besides this, more profound Ayurveda have been mentioned different complications of Madhumeha. These two types of diabetics have been described to be treated on two different lines of management. Its aetiopathogenesis, clinical presentation, complications as well as treatment modalities, appear well comparable to the latest knowledge of conventional medicine. Thus, the present concept will be providing a new outlook about the understanding of aetiopathogenesis and as well management of Diabetic neuropathy. Keywords: Ayurveda, Preameha, Madhumeha, Diabetes mellitus, diabetic neuropathy


2004 ◽  
Vol 147 (6) ◽  
pp. 1017-1023 ◽  
Author(s):  
Michael Ragosta ◽  
Habib Samady ◽  
Ross B Isaacs ◽  
Lawrence W Gimple ◽  
Ian J Sarembock ◽  
...  




2013 ◽  
Vol 92 (9) ◽  
pp. 1189-1194 ◽  
Author(s):  
Cigdem Pala ◽  
Ilker Altun ◽  
Yavuz Koker ◽  
Fatih Kurnaz ◽  
Serdar Sivgin ◽  
...  


2018 ◽  
Vol 7 (10) ◽  
pp. 343 ◽  
Author(s):  
Pin-Pin Wu ◽  
Chew-Teng Kor ◽  
Ming-Chia Hsieh ◽  
Yao-Peng Hsieh

Background: Glucose is one of the constituents in hemodialysates and peritoneal dialysates. How the dialysis associates with the incident diabetes mellitus (DM) remains to be assessed. Methods: The claim data of end-stage renal disease (ESRD) patients who initiated dialysis from and a cohort of matched non-dialysis individuals from 2000 to 2013 were retrieved from the Taiwan National Health Insurance Research Database to examine the risk of incident DM among patients on hemodialysis (HD) and peritoneal dialysis (PD). Predictors of incident DM were determined for HD and PD patients using Fine and Gray models to treat death as a competing event, respectively. Results: A total of 2228 patients on dialysis (2092 HD and 136 PD) and 8912 non-dialysis individuals were the study population. The PD and HD patients had 12 and 97 new-onset of DM (incidence rates of 15.98 and 8.69 per 1000 patient-years, respectively), while the comparison cohort had 869 DM events with the incidence rate of 15.88 per 1000 patient-years. The multivariable-adjusted Cox models of Fine and Gray method showed that the dialysis cohort was associated with an adjusted hazard ratio (HR) of 0.49 (95% CI 0.39–0.61, p value < 0.0001) for incident DM compared with the comparison cohort. The adjusted HR of incident DM was 0.46 (95% CI 0.37–0.58, p value < 0.0001) for HD and 0.84 (95% CI 0.47–1.51, p value = 0.56) for PD. Conclusions: ESRD patients were associated with a lower risk of incident DM. HD was associated with a lower risk of incident DM, whereas PD was not.



Cytokine ◽  
2017 ◽  
Vol 92 ◽  
pp. 75-79 ◽  
Author(s):  
Giuseppe Derosa ◽  
Carmelo Libetta ◽  
Pasquale Esposito ◽  
Ilaria Borettaz ◽  
Carmine Tinelli ◽  
...  


2010 ◽  
Vol 31 (9) ◽  
pp. 1230-1249
Author(s):  
Emily F. Shortridge ◽  
Cara V. James

African Americans are disproportionately represented among patients with end-stage renal disease (ESRD). ESRD is managed with a strict routine that might include regular dialysis as well as dietary, fluid intake, and other lifestyle changes. In a disease such as this, with such disruptive treatment modalities, marriage, specifically, and its ties to well-being have the potential to significantly affect adherence to medical treatment and lifestyle recommendations as well as downstream health outcomes such as disease progression and mortality. The authors used data from the Dialysis Morbidity and Mortality Study, Wave 2, of the U.S. Renal Data System Database, a prospective study of 4,000 ESRD patients selected from a random sample of 25% U.S. dialysis facilities, to investigate these research questions. They found that married African American ESRD patients had marginally better outcomes on several clinical and psychosocial measures, which they hypothesize may be attributable to the instrumental and emotional support conferred by marriage.



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