scholarly journals Assessment of Prevalence and Risk Factors of Dry Eye Disease among Study Group

2020 ◽  
Vol 9 (3) ◽  
pp. 1-4
Author(s):  
Madhavi Chevuturu
Keyword(s):  
Risk Factors ◽  
Dry Eye ◽  
Contact Lens ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Study Group ◽  
Ocular Allergy ◽  
Ocular Surgery ◽  
Steroid Use ◽  
The Difference

Background: Dry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance.   The present study was conducted to assess prevalence and risk factors of dry eye diseases among the study group. Subjects and Methods:  The present study was conducted from February 2018 to July 2018 on 184 patients of both genders visiting the Department of Ophthalmology Mediciti institute of medical sciences with eye complaints. Slit-lamp biomicroscopy with a cobalt blue filter was used to investigate the tear film layer, and the interval from the last blink to the appearance of the first random dry spot on the cornea was noted. Schirmer’s test was performed. Whatman filter paper no 41 was placed in the lower fornix at the lateral one-third of the lower lid margin. Results: Age groups 40-50 years had 52, 50-60 years had 98 and 60-70 years had 34 patients. There were 110 males and 74 females. The difference was significant (P< 0.05). 64 (58.1%) males and 40 (54%) had a dry eye disease. The prevalence found to be 61.9%. The severity of DED was mild in 25%, moderate in 46% and severe in 29%. The difference was significant (P< 0.05). Risk factors of DED were steroid use in 14%, smoking in 56%, alcoholism in 24%, computer job in 78%, systemic allergy in 4%, ocular allergy in 32%, contact lens use in 17% and previous ocular surgery in 7%. The difference was significant (P< 0.05). Conclusion: The author found that the prevalence rate of dry eyes was 61.9%. Risk factors of DED were steroid use, smoking, alcoholism, computer job, systemic allergy, ocular allergy, contact lens use and previous ocular surgery.

scholarly journals Prevalence and risk factors of dry eye disease among University Students in Bangkok, Thailand

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258217
Author(s):  
Chantaka Supiyaphun ◽  
Passara Jongkhajornpong ◽  
Sasivimol Rattanasiri ◽  
Kaevalin Lekhanont
Keyword(s):  
Risk Factors ◽  
University Students ◽  
Dry Eye ◽  
Contact Lens ◽  
Screen Time ◽  
Dry Eye Disease ◽  
Health Study ◽  
Eye Disease ◽  
Associated Risk Factors ◽  
Thai University

Purpose To investigate the prevalence of dry eye disease (DED) and its associated risk factors among Thai university students. Methods A cross-sectional study using an electronic survey was conducted in two Rajabhat universities in Bangkok, Thailand. The woman’s health study questionnaire was used to determine students with DED. The prevalence of DED along with 95% confidence interval (CI) were calculated. Logistic regression model was used to identify the associated risk factors. Results A total of 4,111 university students joined and completed the survey questionnaires. Mean age was 18.8 ± 1.1 years with female predominance (2874 students, 69.91%). Clinically diagnosed DED was reported in 136 students (3.31%), while severe symptoms of eye dryness and irritation were reported in 227 students (5.52%). The prevalence of DED among Thai university students was 8.15% (95% CI 7.33% to 9.02%). History of contact lens use and high screen time (> 8 hours per day) were reported in 868 students (21.11%) and 2101 students (51.11%), respectively. Male gender, contact lens use and high screen time were significantly associated with higher risk of DED with the adjusted ORs (95% CI) of 1.39 (1.09, 1.77), 2.49 (1.96, 3.17), and 1.43 (1.14, 1.80), respectively. Conclusions DED is not rare among Thai university students. Contact lens use and high screen time are two significant modifiable risk factors of DED in our students. These findings can raise awareness of DED in youth population and provide valuable information for public health promotion in university students.

scholarly journals Gout as a Risk Factor for Dry Eye Disease: A Population-Based Cohort Study

2019 ◽  
Vol 8 (1) ◽  
pp. 62 ◽  
Author(s):  
Chia-Yi Lee ◽  
Hung-Chi Chen ◽  
Chi-Chin Sun ◽  
Hung-Yu Lin ◽  
Ko-Hsiu Lu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dry Eye ◽  
Dry Eye Disease ◽  
Age Related Macular Degeneration ◽  
Eye Disease ◽  
Cumulative Probability ◽  
Control Group ◽  
Study Group ◽  
Research Database ◽  
Increased Risk

This study evaluated the effect of gout on the risk of dry eye disease (DED) by using the National Health Insurance Research Database (NHIRD). Data for 30,192 gout patients (21,081 men and 9111 women) and 30,192 non-gout patients (21,005 men and 9187 women) were analyzed. Approximately 1 million patients were randomly sampled from the NHIRD registry. After applying exclusion criteria, patients diagnosed with gout were enrolled in the study group. Thereafter, each individual in the study group underwent the matching process via the propensity score with another non-gout individual, which constituted the control group. The main outcome was defined as the development of DED in accordance with the corresponding International Classification of Diseases, Ninth Revision. In addition to DED, other risk factors including age, sex, and urbanization, and several co-morbidities were included in the multivariate model. The incidence of DED with the adjusted hazard ratio (aHR) and cumulative probability were evaluated in the gout and non-gout patients. A total of 2913 DED events were observed in the study group, whereas 2631 DED events were observed in the control group. A higher incidence rate ratio was found in the study group after adjustment (aHR: 1.065). Moreover, the cumulative probability indicated a significantly increased risk of DED in the study group (p = 0.001). The other potential risk factors of DED according to the multivariate analysis include older age, female gender, higher degree of urbanization, keratopathy, age-related macular degeneration, glaucoma, cataract, ischemic heart disease, hyperlipidemia, peripheral vascular disease, chronic pulmonary disease, rheumatic disease, peptic ulcer disease, liver disease, and malignancy. In conclusion, gout increased the risk of DED after adjustment, and the risk is positively correlated to a longer disease period.

scholarly journals A Questionnaire-Based Assessment of Functional Dry Eye Disease in Working-class Population in Shanghai, China

2021 ◽  
Author(s):  
Nianhong Wang ◽  
Dan Chen ◽  
Yan Liu ◽  
Huan Weng ◽  
Huiying Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Working Class ◽  
Dry Eye ◽  
Contact Lens ◽  
Protective Factor ◽  
Dry Eye Disease ◽  
Current Status ◽  
Eye Disease ◽  
Air Conditioner ◽  
Corneal Staining

Abstract Background To investigate the current status, morbidity, and risk factors of functional dry eye disease (DED) in Shanghai's working-class population. On this basis, exploring measures and methods to fundamentally cure and prevent functional DED. Methods A questionnaire form was used to record the data of the diagnosed functional DED working-class subjects in Shanghai, the results were recorded and analyzed. Additionally, the subjective symptoms of DED subjects and the respective clinical results were also recorded. The classification and corneal staining between subjects who wear contact lens or without were compared. The correlation of classification and corneal staining with their risk factors were also analyzed. Results The risk factors of functional DED showed much in common though their works have professional particularity. EDE accounts for a large proportion of DED (45.35%), many subjects coexist symptoms and signs of mixed DED (32.64%). The age of 21–40 is the peak year range (70.4%). Contact lens, visual terminals, air-conditioner, decoration, stay up later, sleep disorder, smoking were risk factors in most functional DED subjects. Notably, contact lens is a leading risk factor to cause functional DED and ocular surface complications (both were p < 0.01), while deep sleep seems to be a protective factor (p < 0.01%). Conclusion The incidence of functional DED in Shanghai is kept in a high level, most risk factors are closely related to daily work and life, while they are almost reversible. Exploring and eradicating these daily risk factors seems to be a more preferable way to fundamentally control and prevent functional DED.

Lack of Social Support and Social Trust as Potential Risk Factors for Dry Eye Disease: JPHC-NEXT Eye Study

2018 ◽  
Author(s):  
Chi Hoang Viet Vu ◽  
Miki Uchino ◽  
Motoko Kawashima ◽  
Akihiro Nishi ◽  
Christopher A. German ◽  
...  
Keyword(s):  
Risk Factors ◽  
Social Support ◽  
Dry Eye ◽  
Potential Risk ◽  
Social Trust ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Potential Risk Factors

scholarly journals The Use of the Esclera Scleral Contact Lens in the Treatment of Moderate to Severe Dry Eye Disease

2016 ◽  
Vol 163 ◽  
pp. 167-173.e1 ◽  
Author(s):  
Sarah La Porta Weber ◽  
Rodrigo Becco de Souza ◽  
José Álvaro Pereira Gomes ◽  
Ana Luisa Hofling-Lima
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Dry Eye Disease ◽  
Eye Disease

scholarly journals The Development of Dry Eye Disease after Surgery-Indicated Chronic Rhinosinusitis: A Population-Based Cohort Study

2020 ◽  
Vol 17 (11) ◽  
pp. 3829
Author(s):  
Chia-Yi Lee ◽  
Kun-Lin Yang ◽  
Chi-Chin Sun ◽  
Jing-Yang Huang ◽  
Hung-Chih Chen ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Dry Eye ◽  
Dry Eye Disease ◽  
Sinus Surgery ◽  
Eye Disease ◽  
Cumulative Probability ◽  
Control Group ◽  
Study Group ◽  
Diagnostic Code ◽  
Research Database

We aim to evaluate the risk of dry eye disease (DED) occurrence in patients with surgery-indicated chronic rhinosinusitis (CRS) via the national health insurance research database in Taiwan. After exclusion, patients with a diagnostic code of CRS and had received functional endoscopic sinus surgery (FESS) were regarded as having surgery-indicated CRS and enrolled in the study group, then each patient in the study group was age- and gender-matched to four non-CRS patients that served as the control group. The outcome was considered as the development of DED and Cox proportional hazard regression was used for the statistical analysis, which involved multiple potential risk factors of DED. A total of 6076 patients with surgery-indicated CRS that received FESS and another 24,304 non-CRS individuals were enrolled after exclusion. There were 317 and 770 DED events in the study group and the control group during the 16-year follow-up interval, and the study group demonstrated a significantly higher adjusted hazard ratio (1490, 95% confidence intervals (CI): 1.303-1.702) of DED development compared to the control group in the multivariable analysis. In addition, the cumulative probability analysis illustrated a positive correlation of DED occurrence and the disease period of surgery-indicated CRS (p < 0.0001). In the subgroup analysis, both genders revealed a higher but not significant incidence of developing DED in the study group. In conclusion, the existence of surgery-indicated CRS will increase the risk of developing DED, which correlated to the disease interval.

Lack of social support and social trust as potential risk factors for dry eye disease: JPHC-NEXT study

2019 ◽  
Vol 17 (2) ◽  
pp. 278-284 ◽  
Author(s):  
Chi Hoang Viet Vu ◽  
Miki Uchino ◽  
Motoko Kawashima ◽  
Kenya Yuki ◽  
Kazuo Tsubota ◽  
...  
Keyword(s):  
Risk Factors ◽  
Social Support ◽  
Dry Eye ◽  
Potential Risk ◽  
Social Trust ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Potential Risk Factors

Incidence and risk factors of symptomatic dry eye disease in Asian Malays from the Singapore Malay Eye Study

2017 ◽  
Vol 15 (4) ◽  
pp. 742-748 ◽  
Author(s):  
Ryan E.K. Man ◽  
Anuradha R. Veerappan ◽  
Shu-Pei Tan ◽  
Eva K. Fenwick ◽  
Charumathi Sabanayagam ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dry Eye ◽  
Dry Eye Disease ◽  
Eye Disease

scholarly journals Corneal Nerve Regeneration after Self-Retained Cryopreserved Amniotic Membrane in Dry Eye Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Thomas John ◽  
Sean Tighe ◽  
Hosam Sheha ◽  
Pedram Hamrah ◽  
Zeina M. Salem ◽  
...  
Keyword(s):  
Nerve Regeneration ◽  
Dry Eye ◽  
Amniotic Membrane ◽  
Signs And Symptoms ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Study Group ◽  
Corneal Sensitivity ◽  
Corneal Nerve

Purpose. To evaluate the efficacy of self-retained cryopreserved amniotic membrane (CAM) in promoting corneal nerve regeneration and improving corneal sensitivity in dry eye disease (DED).Methods. In this prospective randomized clinical trial, subjects with DED were randomized to receive CAM (study group) or conventional maximum treatment (control). Changes in signs and symptoms, corneal sensitivity, topography, and in vivo confocal microscopy (IVCM) were evaluated at baseline, 1 month, and 3 months.Results. Twenty subjects (age 66.9 ± 8.9) were enrolled and 17 completed all follow-up visits. Signs and symptoms were significantly improved in the study group yet remained constant in the control. IVCM showed a significant increase in corneal nerve density in the study group (12,241 ± 5083 μm/mm2at baseline, 16,364 ± 3734 μm/mm2at 1 month, and 18,827 ± 5453 μm/mm2at 3 months,p=0.015) but was unchanged in the control. This improvement was accompanied with a significant increase in corneal sensitivity (3.25 ± 0.6 cm at baseline, 5.2 ± 0.5 cm at 1 month, and 5.6 ± 0.4 cm at 3 months,p<0.001) and corneal topography only in the study group.Conclusions. Self-retained CAM is a promising therapy for corneal nerve regeneration and accelerated recovery of the ocular surface health in patients with DED. The study is registered at clinicaltrials.gov with trial identifier:NCT02764814.

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