scholarly journals Septic polyarthritis presentation of three cases

2020 ◽  
pp. 32-35
Author(s):  
Nadia Riscanevo ◽  
Elisa Novatti ◽  
Janet Flores ◽  
Diego Baenas ◽  
Francisco Caeiro ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Septic Arthritis ◽  
High Mortality ◽  
Structural Damage ◽  
Clinical Suspicion ◽  
Medical Emergency ◽  
Hematogenous Spread ◽  
Spread Of Infection ◽  
Joint Lavage ◽  
Septic Polyarthritis

Polyarticular septic arthritis is defined as the infection of two or more joints, almost always of bacterial etiology and hematogenous spread. It is considered a medical emergency, which should be recognized early, avoiding the spread of infection, associated with high mortality and the risk of joint structural damage. We present three cases of polyarticular septic arthritis, highlighting the importance of clinical suspicion and early synovial fluid study for diagnosis and treatment with antimicrobials, joint evacuation and joint lavage.

scholarly journals Septicaemic Melioidosis Complicated by Septic Arthritis in A Bangladeshi male: A Case Report

2018 ◽  
Vol 29 (2) ◽  
pp. 94-96
Author(s):  
Hasna Fahmima Haque ◽  
Suchismita Debnath ◽  
Samira Rahat Afroze ◽  
Farhana Afroz ◽  
Muhammad Abdur Rahim ◽  
...  
Keyword(s):  
Case Report ◽  
Synovial Fluid ◽  
Septic Arthritis ◽  
Burkholderia Pseudomallei ◽  
Clinical Suspicion ◽  
High Index ◽  
Uncommon Disease ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Melioidosis is an uncommon disease in Bangladesh but in recent years increasing numbers of cases are being diagnosed. A case of septicaemic melioidosis occurring in a young Bangladeshi returning worker is reported here. The patient presented with fever and features of septic arthritis. Diagnostic work-up revealed the growth of Burkholderia pseudomallei from blood and synovial fluid cultures. This case highlights the importance of high index of clinical suspicion for melioidosis in appropriate clinical scenario.Bangladesh J Medicine Jul 2018; 29(2) : 94-96

scholarly journals Acute Streptococcus mitis Sacroiliitis in a Teenager with Unclear Source of Bacteremia: A Case Report and Literature Review

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Fatma Al-Farsi ◽  
Ibrahim Al-Busaidi ◽  
Khalfan Al-Zeedi
Keyword(s):  
Septic Arthritis ◽  
Bacterial Endocarditis ◽  
Hematogenous Spread ◽  
Streptococcus Mitis ◽  
Rare Form ◽  
Osteoarticular Infections ◽  
Prosthetic Joint ◽  
Septic Sacroiliitis ◽  
Spread Of Infection ◽  
Viridans Group Streptococci

Septic arthritis is an orthopedic emergency that is commonly caused by Staphylococcus aureus. Old age, diabetes mellitus, rheumatoid arthritis, prosthetic joint, and recent surgery are the main predisposing risk factors. Most cases of septic arthritis are caused by hematogenous spread of infection. Infectious sacroiliitis is a rare form of septic arthritis which is often clinically challenging to diagnose due its various and nonspecific presentations. Streptococcus mitis belongs to viridans group streptococci (VGS) bacteria, which is a component of body flora that is commonly involved in bacterial endocarditis. VGS in general and S. mitis specifically is an uncommon cause of osteoarticular infections. Here, we report a case of spontaneous Streptococcus mitis bacteremia complicated by septic sacroiliitis in a healthy teenager in the absence of infective endocarditis or a clear source of bacteremia.

scholarly journals Pediatric Septic Arthritis of the Knee Due to a Multi-Sensitive Streptococcus pyogenes Strain Responsive to Clindamycin—A Case Report

Children ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 189
Author(s):  
Giada Maria Di Pietro ◽  
Irene Maria Borzani ◽  
Sebastiano Aleo ◽  
Samantha Bosis ◽  
Paola Marchisio ◽  
...  
Keyword(s):  
Septic Arthritis ◽  
Streptococcus Pyogenes ◽  
Antibiotic Sensitivity ◽  
Antimicrobial Treatment ◽  
Antibiotic Regimen ◽  
Hematogenous Spread ◽  
Clinical Resistance ◽  
Antibiotic Sensitivity Test ◽  
Clinical Conditions

Septic arthritis is an inflammatory process usually generated by a bacterial infection. The knee is one of the most frequently involved joints. The etiology varies depending on age, and hematogenous spread remains the primary cause in children. Herein, we report a case of a previously healthy three-year-old female who was referred to our institution for acute swelling of her right knee. After a clinical and radiological diagnosis of septic arthritis, an empirical treatment with a combination of cefotaxime and clindamycin was initiated. The isolation of a multi-sensitive Streptococcus pyogenes strain from the joint’s effusion prompted the discontinuation of clindamycin and the usage of cefotaxime alone. One week later, an ultrasound was executed due to worsening in the patient’s clinical conditions, and an organized corpuscular intra-articular effusion with diffuse synovial thickening was revealed. Cefotaxime was therefore replaced with clindamycin, which improved the symptoms. Despite the antibiotic sensitivity test having revealed a microorganism with sensitivity to both cephalosporin and clindamycin, clinical resistance to cefotaxime was encountered and a shift in the antimicrobial treatment was necessary to ensure a full recovery. This case study confirms that an antibiotic regimen based solely on a susceptibility test may be ineffective for such cases.

scholarly journals Novel therapeutic interventions towards improved management of septic arthritis

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jian Wang ◽  
Liucai Wang
Keyword(s):  
Antibiotic Therapy ◽  
Septic Arthritis ◽  
Clinical Success ◽  
Treatment Protocol ◽  
Current Treatment ◽  
Therapeutic Interventions ◽  
Medical Emergency ◽  
Success Rates ◽  
Joint Infections ◽  
Novel Therapeutic

AbstractSeptic arthritis (SA) represents a medical emergency that needs immediate diagnosis and urgent treatment. Despite aggressive treatment and rapid diagnosis of the causative agent, the mortality and lifelong disability, associated with septic arthritis remain high as close to 11%. Moreover, with the rise in drug resistance, the rates of failure of conventional antibiotic therapy have also increased. Among the etiological agents frequently isolated from cases of septic arthritis, Staphylococcus aureus emerges as a dominating pathogen, and to worsen, the rise in methicillin-resistant S. aureus (MRSA) isolates in bone and joint infections is worrisome. MRSA associated cases of septic arthritis exhibit higher mortality, longer hospital stay, and higher treatment failure with poorer clinical outcomes as compared to cases caused by the sensitive strain i.e methicillin-sensitive S. aureus (MSSA).In addition to this, equal or even greater damage is imposed by the exacerbated immune response mounted by the patient’s body in a futile attempt to eradicate the bacteria. The antibiotic therapy may not be sufficient enough to control the progression of damage to the joint involved thus, adding to higher mortality and disability rates despite the prompt and timely start of treatment. This situation implies that efforts and focus towards studying/understanding new strategies for improved management of sepsis arthritis is prudent and worth exploring.The review article aims to give a complete insight into the new therapeutic approaches studied by workers lately in this field. To the best of our knowledge studies highlighting the novel therapeutic strategies against septic arthritis are limited in the literature, although articles on pathogenic mechanism and choice of antibiotics for therapy, current treatment algorithms followed have been discussed by workers in the past. The present study presents and discusses the new alternative approaches, their mechanism of action, proof of concept, and work done so far towards their clinical success. This will surely help to enlighten the researchers with comprehensive knowledge of the new interventions that can be used as an adjunct therapy along with conventional treatment protocol for improved success rates.

Early diagnosis of septic arthritis using synovial fluid presepsin: A preliminary study

2019 ◽  
Vol 25 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Takashi Imagama ◽  
Atsunori Tokushige ◽  
Kazushige Seki ◽  
Toshihiro Seki ◽  
Daisuke Nakashima ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Early Diagnosis ◽  
Septic Arthritis ◽  
Preliminary Study

scholarly journals Fatal Chromobacterium violaceum septicemia in a South Indian adult

2012 ◽  
Vol 6 (10) ◽  
pp. 751-755 ◽  
Author(s):  
Rajiv Karthik ◽  
Padmaja Pancharatnam ◽  
Veeraraghavan Balaji
Keyword(s):  
Mortality Rate ◽  
Antibiotic Therapy ◽  
Septic Arthritis ◽  
High Mortality ◽  
South India ◽  
Chromobacterium Violaceum ◽  
Human Pathogen ◽  
Tropical Regions ◽  
First Case ◽  
South Indian

Chromobacterium violaceum is a rare human pathogen that causes potentially fatal infections especially in the tropical regions. Limited awareness about this pathogen and inappropriate antibiotic therapy are some of the factors contributing to the high mortality rate. To date there have been only eight cases reported from India of which only one is an adult. To the best of our knowledge, we report here the first case of a 40-year-old man from South India with septicemic C. Violaceum infection and septic arthritis.

Intrasellar Abscess after Transsphenoidal Pituitary Adenomectomy

Neurosurgery ◽  
1983 ◽  
Vol 12 (6) ◽  
pp. 684-686 ◽  
Author(s):  
Bernard Robinson
Keyword(s):  
Mortality Rate ◽  
Rare Disease ◽  
High Mortality ◽  
Sella Turcica ◽  
Clinical Suspicion ◽  
Laboratory Studies ◽  
Successful Therapy ◽  
Proper Diagnosis

Abstract Intrasellar abscess is a rare disease that is difficult to diagnose preoperatively. Few neurosurgeons who operate by the transsphenoidal route are concerned with intrasellar abscess despite its high mortality rate. We describe a case of intrasellar abscess which, to our knowledge, is only the second diagnosed or suspected preoperatively. Most cases have been diagnosed unexpectedly at operation or autopsy. This case also is the first reported intrasellar abscess arising within an intrasellar graft used to seal the sella turcica after transsphenoidal pituitary adenomectomy. The clinical suspicion of infection proved more reliable than roentgenograms and laboratory studies in leading to the proper diagnosis and successful therapy.

scholarly journals Clinical suspicion is key: an unusual presentation of septic arthritis after distal pancreatectomy

2019 ◽  
Vol 2019 (6) ◽  
Author(s):  
Joel M Prince ◽  
Ji Fan ◽  
Subhasis Misra
Keyword(s):  
Abdominal Surgery ◽  
Septic Arthritis ◽  
Distal Pancreatectomy ◽  
Splenic Artery ◽  
Infectious Agent ◽  
Clinical Suspicion ◽  
Unusual Presentation ◽  
Exact Etiology ◽  
Rapid Destruction

Abstract Septic arthritis is the result of an infectious agent gaining access a sterile joint. This results in a devastating inflammatory response that leads to rapid destruction of intra-articular cartilage and with it significant morbidity. This case study reports an unusual presentation of septic arthritis following abdominal surgery; specifically, a distal pancreatectomy performed for an enlarged, mid-body pancreas mass involving the splenic artery. This is the first reported case of septic arthritis following abdominal surgery, though the exact etiology is unknown.

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