scholarly journals Ayurveda and Modern Perspective on Rajonivrittiw.s.r. to Menopause: Review Based on Literary Study

2021 ◽  
Vol 04 (11) ◽  
pp. 109-113
Author(s):  
Monika Kumari ◽  
Mahesh Dixit ◽  
Narendra Kumar Meena
Keyword(s):  
Hormone Replacement ◽  
Cost Effective ◽  
Modern Medicine ◽  
The Body ◽  
Term Therapy ◽  
Cost Effective Treatment ◽  
Long Term Therapy ◽  
Modern Perspective

Menopause, a phenomenon unique to women, is the ending of a woman’s monthly menstrual period and ovulation. It, alongside, several other changes in the bodyand mind, brought in due to a decline in the amount of the hormones estrogen and progesterone being produced by the body. Menopause is, occasionally, viewed as an end to youth and sexuality, making it a socially unacceptable occurrence. Menopause, though,one of the important physical and mental milestones in a woman’s life, many women lack information about what is taking place and what are their options. There comes the role of Ayurveda , in Ayurveda literature there is no detailed description of Rajonivrittior menopause except the age of Rajonivrittiis given as 50 years. Ayurveda involves a holistic physiological system based on balance, with its cardinal doctrine of human physiology being constituted by “vata”, “pitta” and “kapha”. In modern medicine the only treatment for these symptoms is Hormone replacement therapy (HRT), which is not a long-term therapy to be given as it has side effects on the overall health of the women. In Ayurveda Dhatu kshaya can be treated with Rasayanatherapy and other symptoms of hypo-estrogenic conditions can be treated with Phytoestrogens. So, Ayurveda gives a non-hormonal and cost-effective treatment for Rajonivrittior Menopause.

Antithrombotic Therapy for DVT/PE

1997 ◽  
Vol 17 (03) ◽  
pp. 161-162
Author(s):  
Thomas Hyers
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight Heparin ◽  
Oral Anticoagulants ◽  
Cost Effective ◽  
Therapeutic Agents ◽  
Great Promise ◽  
Term Therapy ◽  
Low Molecular Weight ◽  
Long Term Therapy

SummaryProblems with unfractionated heparin as an antithrombotic have led to the development of new therapeutic agents. Of these, low molecular weight heparin shows great promise and has led to out-patient therapy of DVT/PE in selected patients. Oral anticoagulants remain the choice for long-term therapy. More cost-effective ways to give oral anticoagulants are needed.

scholarly journals Effect of estrogens and their metabolites genotoxicity on the pathogenesis and progression of estrogen-dependent breast cancer

2019 ◽  
Vol 73 ◽  
pp. 909-919
Author(s):  
Ewa Sawicka ◽  
Arkadiusz Woźniak ◽  
Małgorzata Drąg-Zalesińska ◽  
Agnieszka Piwowar
Keyword(s):  
Mammary Gland ◽  
Hormone Replacement ◽  
Modern Medicine ◽  
The Body ◽  
Mammary Gland Tissue ◽  
Oncological Diseases ◽  
17Β Estradiol ◽  
Estradiol Metabolites ◽  
Genotoxic Action

Oncological diseases, due to the still increasing morbidity and mortality, are one of the main problems of modern medicine. Cancer of the mammary gland is the most common cancer among women around the world, and is the second cause of cancer deaths in this group, immediately after lung cancer. This kind of cancer belongs to an estrogen-dependent cancer, with proven associations with hormonal disorders in the body, occurring especially in the perimenopausal period and among women using hormone replacement therapy, as well as a result of the action of various xenobiotics that may interact with the estrogen receptor. Hormone steroids are widely used in medicine and their side effects are constantly discussed. The role of these compounds and their metabolites in maintaining hormonal balance is well understood, while many studies indicate the possible contribution of these steroids in the progression of the cancer process, especially in mammary gland tissue. Therefore, the genotoxic action of this group of compounds is still studied. Due to the limited number of scientific reports, the aim of this paper was to review and critically analyze data from the literature regarding the participation of estrogens (17β-estradiol) and their metabolites (2-methoxy estradiol, 4-hydroxy estradiol, 16α-hydroxyestrone) in the induction of carcinogenesis in mammary gland, in particular concerning the genotoxic activity of 17β-estradiol metabolites.

scholarly journals A Randomized Open Clinical Study of the Atherosclerosis Treatment Information Video Effect on Adherence to Long-Term Therapy in Patients with Cardiovascular Diseases

2021 ◽  
Vol 17 (5) ◽  
pp. 683-687
Author(s):  
Yu. V. Bulaeva ◽  
E. A. Naumova ◽  
O. N. Semenova ◽  
T. V. Kanaeva ◽  
K. A. Popov ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Patient Adherence ◽  
Intervention Group ◽  
Cardiovascular Complications ◽  
The Body ◽  
Term Therapy ◽  
Control Group ◽  
Treatment Information ◽  
Long Term Therapy

Aim. Study the effect of a study video, which was created by researchers and devoted to the atherosclerosis development and the effect of statin therapy on atherosclerotic plaque, on adherence to long-term therapy in patients with high or very high risk of cardiovascular complications.Material and methods. 120 patients admitted to hospital with cardiovascular diseases were included in the study. Patients were randomized into 2 groups: in the main group (n=60), the information video edited by the researchers was shown to patients on the eve of discharge, in addition to a printed brochure on lifestyle and diet modification, and in the control group (n=60), patients were given only a standard brochure. The motivating video shows the damage to the cardiovascular system by the atherosclerotic process and the beneficial effect on the body of constant intake of statins. After 1 and 3 months after discharge from the hospital, telephone calls were made, after which the patients had to visit the center for an objective examination by a researcher and control of laboratory parameters. After 1 month, 110 patients visited the center, after 3 months, 98 respondents visited the center.Results. The group with the information video demonstration noted more frequent adherence to medical recommendations compared to the control: after 1 month, 52 (96%) patients continued treatment versus 48 (86%) patients, 3 months after discharge 48 (96%) patients continued treatment versus 38 (79%) patients (p<0.05). After 1 month, 38 (70%) patients in the intervention group continued taking statins versus 29 (43%) respondents in the control group (p<0.05), 3 months after discharge, 40 (80%) patients in the intervention group continued to take statins versus 33 (69%) control patients (p<0.09).Conclusion. Demonstration of a motivating video about the effect of statins on the atherosclerosis course increases patient adherence to medicinal therapy, including adherence to statins.

scholarly journals The role of diuretics in the treatment of hypertension: a focus on chlorthalidone (lecture)

HYPERTENSION ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 12-29
Author(s):  
Yu.M. Sirenko
Keyword(s):  
Cardiovascular Complications ◽  
Term Therapy ◽  
Thiazide Diuretics ◽  
Cerebrovascular Complications ◽  
Hypertension Therapy ◽  
Long Term Therapy ◽  
The Impact ◽  
Therapy Of Hypertension

The lecture discusses the role of thiazide and thiazide-like diuretics, in particular chlorthalidone, in the modern treatment of arterial hypertension. The modern concepts about the mechanism of action of thiazide diuretics and chlorthalidone are presented. Differences in the degree of antihypertensive effect of hydrochlorothiazide and chlorthalidone are discussed. The results of large randomized trials SHEP, MRFIT, ALLHAT were analyzed, in which chlorthalidone therapy significantly reduced the risk of developing cardiovascular and cerebrovascular complications of hypertension. The effect of thiazide diuretics on glucose metabolism and the impact of carbohydrate metabolism disorders during treatment with chlorthalidone on the risk of cardiovascular complications was considered. The lecture also discusses the effect of chlorthalidone therapy on kidney function, the possibility of its use in chronic kidney disease. The data are presented on the prevention of resistant hypertension and chro-nic heart failure during long-term therapy of hypertension with chlorthalidone. The frequency and terms of the development of side effects of hypertension therapy with thiazide-like diuretics were also analyzed.

Immunoregulation of Autoimmune Disorders: The Role of Intravenous Immunoglobulins

1993 ◽  
Vol 16 (5_suppl) ◽  
pp. 189-195 ◽  
Author(s):  
G. Luzi ◽  
R. Ferrara
Keyword(s):  
Hematologic Malignancies ◽  
Intravenous Immunoglobulins ◽  
Term Therapy ◽  
Immune Modulators ◽  
Bacterial Diseases ◽  
Immunoglobulin Preparations ◽  
Original Observation ◽  
Long Term Therapy

Modified and intact immunoglobulin preparations are available for therapeutic use. The administration of intravenous immunoglobulins (IVI G) gave positive results in Primary Immunodeficiency Syndromes (PIS) (prophylaxis of viral and bacterial diseases), in treatment of secondary immunodeficiencies (hematologic malignancies, bone marrow transplantation), and in some infections. Adverse reactions have been reported during IVIG infusions, but they are rarely serious and do not represent limiting conditions for a short or long term therapy. After the original observation in thrombocytopenic purpura, IVIG have been used as immune modulators in various autoimmune related disorders. Various mechanisms of action are proposed: blockade and down regulation of phagocytic function via Fc receptor, regulation of idiotype-anti idiotype network, suppression of idiotype synthesis, T-B cell interference towards antigen presentation, increase in suppressor lymphocytes, IVIG-cytokine interaction.

scholarly journals Sustained hemodynamic improvement during long-term therapy with levodopa in heart failure: Role of plasma catecholamines

1987 ◽  
Vol 10 (6) ◽  
pp. 1286-1293 ◽  
Author(s):  
Sol I. Rajfer ◽  
James D. Rossen ◽  
John W. Nemanich ◽  
Frank L. Douglas ◽  
Fetima Davis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Plasma Catecholamines ◽  
Term Therapy ◽  
Hemodynamic Improvement ◽  
Long Term Therapy

scholarly journals Managing treatment fatigue in patients with multiple sclerosis on long-term therapy: the role of multiple sclerosis nurses

2014 ◽  
pp. 1093 ◽  
Author(s):  
Robert Ristuccia ◽  
Jewell Sally ◽  
Ann Crawford ◽  
Holly Mara ◽  
Laura McCatty ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Term Therapy ◽  
Long Term Therapy

Anxiolytics in the Treatment of Behavioral and Psychological Symptoms of Dementia

2000 ◽  
Vol 12 (S1) ◽  
pp. 281-289 ◽  
Author(s):  
Hervé Allain ◽  
Stéphane Schück ◽  
Danièle Bentué-Ferrer ◽  
Michel Bourin ◽  
Martine Vercelletto ◽  
...  
Keyword(s):  
Psychological Symptoms ◽  
Behavioral Therapy ◽  
Term Therapy ◽  
Drug Classes ◽  
Advanced Stages ◽  
Emergency Measure ◽  
Long Term Therapy ◽  
Behavioral And Psychological Symptoms

By definition, anxiolytics are drugs capable of treating anxiety and anxiety related disorders. The precise role of anxiolytics, particularly in comparison with other drug classes (e.g., antipsychotics and antidepressants) and other therapeutic approaches (e.g., psychotherapy, behavioral therapy, and relaxation) in treating behavioral and psychological symptoms of dementia (BPSD) needs to be determined. If anxiolytics are used for BPSD, the clinician must decide whether they should be used as an emergency measure, as long-term therapy, or both. Also, whether anxiolytics are useful in treating anxiety and its consequences in both the early and advanced stages of dementia must be considered.

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